Vitiligo and Pernicious Anemia

Allison, J R; Curtis, Arthur C.

doi:10.1001/archderm.1955.03730350009002

Cited by 71 publications

(18 citation statements)

References 2 publications

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“…4,5 Literature of AA quotes many incidences of association with other autoimmune diseases like lupus erythematoses, pernicious anemia, ulcerative colitis, lichen planus, myasthenia gravis etc. 18,20,21 Except for a single case of lichen planus we did not have any other associated autoimmune disorder.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological and clinical characteristics of alopecia areata: an observational study from South India

2018

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Background: Paucity of literature on epidemiological studies of alopecia areata (AA) from Indian subcontinent especially from southern India. The objectives of the study were to study the epidemiological and clinical profile of alopecia areata in a population from northern part of South India.Methods: The epidemiology including pattern, risk factors and associations were evaluated in all newly diagnosed alopecia areata cases seen from January 2017 to December 2017 in a tertiary hospital in South India.Results: The incidence of AA was 2% of total dermatology outpatients. 60 new case referrals of AA were seen from January 2017 to December 2017. Male to female ratio was almost equal. Maximum number of patients with AA belonged to the age group of 21-40 years (50%). Occiput was the commonest site involved in AA (36.8%) followed by vertex (27.6%). 30% of the patients gave a past history of AA and 21.7% gave a family history of AA. 15% of AA patients had history of atopy. Nail changes were found in 30% of patients. 5% of AA patients had associated vitiligo. On microscopic examination of plucked hair early dystrophic anagen hair predominated (70%) as against (16.7%) of dystrophic telogen hair.Conclusions: The clinical characteristics of alopecia areata throws light from a data sparse geographical region but warrants further detailed studies for improved understanding.

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Section: Discussionmentioning

confidence: 99%

Epidemiological and clinical characteristics of alopecia areata: an observational study from South India

2018

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“…There is evidence suggesting that vitiligo is an autoimmune disease: (1) high frequency of the association with other autoimmune diseases, such as thyroid diseases, pernicious anemia and diabetes mellitus [1,4,5,9,15]; (2) high incidence of various autoantibodies in sera [2][3][4]; (3) the presence of antimelanin antibodies in the sera [14].…”

Section: Discussionmentioning

confidence: 99%

Treatment of Vitiligo with Oral Corticosteroids

Imamura¹,

Tagami²

1976

Dermatology

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17 patients with generalized vitiligo and 5 patients with localized vitiligo were treated with oral corticosteroids. Six patients with generalized vitiligo showed over 75% repigmentation in at least one of the patches. Two patients with generalized vitiligo and 1 patient with localized vitiligo showed a partial repigmentation of 25-75%, while 5 patients with generalized vitiligo and 1 patient with localized vitiligo showed a minimal repigmentation of less than 25%. Four patients with generalized vitiligo and 3 patients with localized vitiligo failed to respond. Repigmentation became evident within 4 weeks in most cases, and in general was more markedly noted in exposed areas.

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“…the cause of vitiligo remains still unknown. The disor der has been reported in association with several endocri nopathies of autoimmune nature including thyroid dis eases, adrenal insufficiency, diabetes mcllitus and autoim mune-type chronic active hepatitis [4][5][6][7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Vitiligo and Other Diseases: Coexistence or True Association?

et al. 1994

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In the past, several authors described an association of vitiligo with autoimmune disorders and the presence of different tissue autoantibodies. A review of the literature showed large differences in the results. Therefore, 321 patients with vitiligo (male/female ratio 114/207) were examined to see whether the frequencies of associated diseases and phenomena (i.e. Koebner phenomenon, canities praecox, halo nevi, poliosis circumscripta), the number of pigmented lesions and the presence of autoantibodies are of significance in order to support (a) a subentity of childhood vitiligo and (b) whether there is a true predisposition or association of autoimmune or other diseases in this group of patients. The data confirm earlier results of a prevalence of thyroid disease and the presence of thyroid antibodies, whereas other diseases are a random event. 6.2% of the patients had congenital nevi compared with 2.8% in a normal healthy population. Based on the results of this study and the significant higher risk for development of melanomas in this patient group, an annual checkup is recommended.

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Vitiligo and Pernicious Anemia

Cited by 71 publications

References 2 publications

Epidemiological and clinical characteristics of alopecia areata: an observational study from South India

Epidemiological and clinical characteristics of alopecia areata: an observational study from South India

Treatment of Vitiligo with Oral Corticosteroids

Vitiligo and Other Diseases: Coexistence or True Association?

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