<p class="abstract"><strong>Background:</strong> Acne is one of the most common disease affecting adolescence. Although prior studies have evaluated epidemiologic patterns of acne in different ethnicities and regions, literature is lacking from this part of the country. The objectives of the study were to delineate the clinical and epidemiological profile of acne vulgaris in a population from northern Kerala in South India.</p><p class="abstract"><strong>Methods:</strong> The study was carried out for 6 months and it included 100 patients. Epidemiology including pattern, aggravating factors, seasonal variation, diet, smoking, markers of androgenecity and associations were evaluated in all newly diagnosed cases of acne vulgaris who attended the outpatient department in Kannur Medical College, Kannur, Kerala, India from January 2018 to June 2018.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 100 patients females (74%) outnumbered males (26%) and although the majority affected belonged to the age group of 21-25 years (38%), adult acne was observed in 28%. Grade 3 acne was the commonest (44%), followed by grade 2 (30%) and grade 4 (18%). Face was affected in all patients with cheeks (91%), followed by forehead (72%), mandible (36%) and chin (28%) and trunk (23%). Scarring was found in 34% and pigmentation in 40%. Family history of acne was observed in 33%.</p><p class="abstract"><strong>Conclusions:</strong> This study brings out the clinical profile of acne in a tertiary care hospital in South India.</p>
<p class="abstract"><strong>Background:</strong> Paucity of literature on epidemiological studies of alopecia areata (AA) from Indian subcontinent especially from southern India. The objectives of the study were to study the epidemiological and clinical profile of alopecia areata in a population from northern part of South India.</p><p class="abstract"><strong>Methods:</strong> The epidemiology including pattern, risk factors and associations were evaluated in all newly diagnosed alopecia areata cases seen from January 2017 to December 2017 in a tertiary hospital in South India.<strong></strong></p><p class="abstract"><strong>Results:</strong> The incidence of AA was 2% of total dermatology outpatients. 60 new case referrals of AA were seen from January 2017 to December 2017. Male to female ratio was almost equal. Maximum number of patients with AA belonged to the age group of 21-40 years (50%). Occiput was the commonest site involved in AA (36.8%) followed by vertex (27.6%). 30% of the patients gave a past history of AA and 21.7% gave a family history of AA. 15% of AA patients had history of atopy. Nail changes were found in 30% of patients. 5% of AA patients had associated vitiligo. On microscopic examination of plucked hair early dystrophic anagen hair predominated (70%) as against (16.7%) of dystrophic telogen hair.</p><p class="abstract"><strong>Conclusions:</strong> The clinical characteristics of alopecia areata throws light from a data sparse geographical region but warrants further detailed studies for improved understanding.</p>
<p class="abstract"><strong>Background:</strong> Foot eczema is caused by several exogenous or endogenous factors acting alone or in combination. Leather, rubber and adhesive components are the most common allergens. Patch test is performed to find out the allergen which helps clinician in subsequent patient management and improving the prognosis. </p><p class="abstract"><strong>Methods:</strong> Total 50 patients with foot eczema were evaluated and patch test was performed with Indian standard series over 18 months period in a tertiary hospital in South India. <strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 50 patients 32 (64%) were females and 18 (36%) were males. Younger age group was mainly involved (second decade). An atopic back ground and seasonal exacerbation were contributory in many. Patch test was positive in 39 (78%) patients. The forefoot was predominantly involved part in 56% followed by dorsal aspect alone of the foot. Scaly plaque was the predominant morphological pattern seen in 25 (50%). Maximum number of patients (24%) showed positive reactions to potassium dichromate and the minimum (2%) to neomycin sulphate. </p><p class="abstract"><strong>Conclusions:</strong> Though rubber and rubber chemicals were the common sensitizers causing foot eczema worldwide, our study found potassium dichromate to be the most common sensitizer which is one the components used in leather tanning and is a constituent of cement, soaps and detergents. </p>
<p class="abstract">Churg Strauss syndrome (CSS) also known as eosinophilic granulomatosis with polyangitis (EGPA), is a rare disease manifested by hypereosinophilia, vasculitis and extravascular granuloma. We report a case of 72 year old male with history of asthma and allergic rhinitis who presented with non-healing ulcer on dorsum of left middle finger and petechial lesions on forearms. Investigations revealed marked eosinophilia, elevated IgE, negative antineutrophil cytoplasmic antibodies (ANCA), histopathologic examination showed granulomatous vasculitis and CSS was diagnosed using ACR criteria. We report this case because of rarity of disease and the importance of recognizing similar presentation for early diagnosis and treatment of this life threatening syndrome.</p>
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