Vitamin E-Blended UHMWPE Biomaterials

Kurtz, Steven M.; Bracco, Pierangiola; Costa, Luigi; Oral, Ebru; Muratoglu, Orhun K.

doi:10.1016/b978-0-323-35401-1.00017-x

Cited by 18 publications

(9 citation statements)

References 27 publications

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“…However, the mechanical properties of GO/UHMWPE composites irradiated at 90 kGy was shown to be insensitive to the irradiation. [26] However, the effect of irradiation on graphene/PE based composites have not been studied. [26] However, the effect of irradiation on graphene/PE based composites have not been studied.…”

Section: Introductionmentioning

confidence: 99%

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Kolanthai

Bose

Bhagyashree

et al. 2015

Phys. Chem. Chem. Phys.

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A unique strategy for scavenging free radicals in situ on exposure to gamma irradiation in polyethylene (PE) nanocomposites is presented. Blends of ultra-high molecular weight PE and linear low-density PE (PEB) and their nanocomposites with graphene (GPEB) were prepared by melt mixing to develop materials for biomedical implants. The effect of gamma irradiation on the microstructure and mechanical properties was systematically investigated. The neat blend and the nanocomposite were subjected to gamma-ray irradiation in order to improve the interfacial adhesion between PE and graphene sheets. Structural and thermal characterization revealed that irradiation induced crosslinking and increased the crystallinity of the polymer blend. The presence of graphene further enhanced the crystallinity via crosslinks between the polymer matrix and the filler on irradiation. Graphene was found to scavenge free radicals as confirmed by electron paramagnetic resonance spectroscopy. Irradiation of graphene-containing polymer composites resulted in the largest increase in modulus and hardness compared to either irradiation or addition of graphene to PEB alone. This study provides new insight into the role of graphene in polymer matrices during irradiation and suggests that irradiated graphene-polymer composites could emerge as promising materials for use as articulating surfaces in biomedical implants.

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Section: Introductionmentioning

confidence: 99%

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Kolanthai

Bose

Bhagyashree

et al. 2015

Phys. Chem. Chem. Phys.

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“…6,15 It is important to highlight that the densities of the fillers are different; therefore, the volume fraction of the Al 2 O 3 is lower than that of the B 4 C. Vitamin E (Aché Laborat orios Farmacêuticos S.A., Brazil) was added at 1% concentration in mass as an antioxidant agent to prevent thermal degradation during hot compression molding. 19…”

Section: Methodsmentioning

confidence: 99%

“…The nanoparticles were mixed with the UHMWPE powder at a total concentration of 3% in mass since literature references show that this concentration is ideal for reinforcing UHMWPE with the nanoparticles used 6,15 . It is important to highlight that the densities of the fillers are different; therefore, the volume fraction of the Al 2 O 3 is lower than that of the B 4 C. Vitamin E (Aché Laboratórios Farmacêuticos S.A., Brazil) was added at 1% concentration in mass as an antioxidant agent to prevent thermal degradation during hot compression molding 19 …”

Section: Methodsmentioning

confidence: 99%

Investigating the effect of simultaneous incorporation of Al₂O₃ and B₄C nanofillers in enhancing the wear performance of UHMWPE

Soares,

Maru,

Almeida

et al. 2024

J of Applied Polymer Sci

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During the past years, great effort has been made to improve the tribological performance of ultra‐high molecular weight polyethylene (UHMWPE), considered a key polymeric material in applications requiring elevated mechanical and corrosion resistance and bioinertness. This work aimed to investigate the role of adding ceramic nanofillers of aluminum oxide (Al2O3) and boron carbide (B4C) in the UHMWPE matrix in order to modify the triboperformance of the polymer. The results obtained through dry reciprocating sliding tests up to 6 h (21,600 cycles) revealed that the presence of nanoparticles has led to a 33% higher coefficient of friction on average when compared with the matrix polymer without nanofillers. This behavior results from the increased resistance to plowing caused by the nanofillers, which contributes to the frictional force. Conversely, the simultaneous utilization of both nanofillers, each one at a concentration of 1.5% by mass, significantly enhances the wear resistance of UHMWPE, achieving a reduction in wear of over 35%.

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“…Vitamin E-blended UHMWPE or HXLPE arose from the need to decrease the production of free radicals. Vitamin E is a biocompatible antioxidant, with multiple beneficial roles (anti-inflammatory, antibacterial), that protects the polymer from oxidative degradation [ 82 , 83 , 84 ]. A-tocopherol is inserted into the material before or after cross-linking irradiation and before sterilization (bulk diffusion technique) [ 85 , 86 , 87 ].…”

Section: Bearing Surfaces and Biomaterials Used In Primary Total Hip ...mentioning

confidence: 99%

Updates on Biomaterials Used in Total Hip Arthroplasty (THA)

et al. 2023

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One of the most popular and effective orthopedic surgical interventions for treating a variety of hip diseases is total hip arthroplasty. Despite being a radical procedure that involves replacing bone and cartilaginous surfaces with biomaterials, it produces excellent outcomes that significantly increase the patient’s quality of life. Patient factors and surgical technique, as well as biomaterials, play a role in prosthetic survival, with aseptic loosening (one of the most common causes of total hip arthroplasty failure) being linked to the quality of biomaterials utilized. Over the years, various biomaterials have been developed to limit the amount of wear particles generated over time by friction between the prosthetic head (metal alloys or ceramic) and the insert fixed in the acetabular component (polyethylene or ceramic). An ideal biomaterial must be biocompatible, have a low coefficient of friction, be corrosion resistant, and have great mechanical power. Comprehensive knowledge regarding what causes hip arthroplasty failure, as well as improvements in biomaterial quality and surgical technique, will influence the survivability of the prosthetic implant. The purpose of this article was to assess the benefits and drawbacks of various biomaterial and friction couples used in total hip arthroplasties by reviewing the scientific literature published over the last 10 years.

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Vitamin E-Blended UHMWPE Biomaterials

Cited by 18 publications

References 27 publications

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Investigating the effect of simultaneous incorporation of Al₂O₃ and B₄C nanofillers in enhancing the wear performance of UHMWPE

Updates on Biomaterials Used in Total Hip Arthroplasty (THA)

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Vitamin E-Blended UHMWPE Biomaterials

Cited by 18 publications

References 27 publications

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Graphene scavenges free radicals to synergistically enhance structural properties in a gamma-irradiated polyethylene composite through enhanced interfacial interactions

Investigating the effect of simultaneous incorporation of Al2O3 and B4C nanofillers in enhancing the wear performance of UHMWPE

Updates on Biomaterials Used in Total Hip Arthroplasty (THA)

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Investigating the effect of simultaneous incorporation of Al₂O₃ and B₄C nanofillers in enhancing the wear performance of UHMWPE