Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells

Grund, Janina C.; Krammer, Susanne; Yang, Zuqin; Mitländer, Hannah; Rauh, Manfred; Zirlik, Sabine; Krause, Alexander; Zimmermann, Theodor; Rieker, Ralf J.; Geppert, Carol I.; Papadopoulos, Nikolaos G.; Finotto, Susetta

doi:10.1016/j.jacig.2023.100099

Journal of Allergy and Clinical Immunology: Global

2023

DOI: 10.1016/j.jacig.2023.100099

|View full text |Cite

Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells

Janina C. Grund¹,

Susanne Krammer²,

Zuqin Yang³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 51 publications

(69 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

Ghaseminejad-Raeini,

Ghaderi,

Sharafi

et al. 2023

Front. Immunol.

View full text Add to dashboard Cite

For many years, vitamin D has been acknowledged for its role in maintaining calcium and phosphate balance. However, in recent years, research has assessed its immunomodulatory role and come up with conflicting conclusions. Because the vitamin D receptor is expressed in a variety of immune cell types, study into the precise role of this molecule in diseases, notably autoimmune disorders, has been made possible. The physiologically activated version of vitamin D also promotes a tolerogenic immunological condition in addition to modulating innate and acquired immune cell responses. According to a number of recent studies, this important micronutrient plays a complex role in numerous biochemical pathways in the immune system and disorders that are associated with them. Research in this field is still relatively new, and some studies claim that patients with severe autoimmune illnesses frequently have vitamin D deficiencies or insufficiencies. This review seeks to clarify the most recent research on vitamin D’s immune system-related roles, including the pathophysiology of major disorders.

show abstract

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

Ghaseminejad-Raeini,

Ghaderi,

Sharafi

et al. 2023

Front. Immunol.

View full text Add to dashboard Cite

show abstract

Gender Differences in the Interplay between Vitamin D and Microbiota in Allergic and Autoimmune Diseases

Murdaca,

Tagliafico,

Page

et al. 2024

Biomedicines

View full text Add to dashboard Cite

The synergic role of vitamin D and the intestinal microbiota in the regulation of the immune system has been thoroughly described in the literature. Vitamin D deficiency and intestinal dysbiosis have shown a pathogenetic role in the development of numerous immune-mediated and allergic diseases. The physiological processes underlying aging and sex have proven to be capable of having a negative influence both on vitamin D values and the biodiversity of the microbiome. This leads to a global increase in levels of systemic inflammatory markers, with potential implications for all immune-mediated diseases and allergic conditions. Our review aims to collect and analyze the relationship between vitamin D and the intestinal microbiome with the immune system and the diseases associated with it, emphasizing the effect mediated by sexual hormones and aging.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Vitamin D3 resolved human and experimental asthma via B lymphocyte–induced maturation protein 1 in T cells and innate lymphoid cells

Cited by 2 publications

References 51 publications

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

Gender Differences in the Interplay between Vitamin D and Microbiota in Allergic and Autoimmune Diseases

Contact Info

Product

Resources

About