Vitamin D stores of urban women in Taipei: Effect on bone density and bone turnover, and seasonal variation

Tsai, Keh–Sung; Hsu, Sandy Huey-Jen; Cheng, Jun; Yang, Rong‐Sen

doi:10.1016/s8756-3282(97)00010-0

Cited by 44 publications

(49 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Indeed, in the present study, secondary hyperparathyroidism was evident in about 22% of the women studied (with serum 25(OH)D <50 nmol/L) with increased bone turnover and significant decreases in the BMD values at both lumbar spine and neck femur. This is consistent with the observed significant association between serum 25(OH)D levels and BMD values in several studies [8,[44][45][46][47][48][49], but contrast with studies in other populations showing no significant associations between serum 25(OH)D levels and BMD values [50][51][52].…”

Section: Discussionsupporting

confidence: 90%

Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

et al. 2010

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 90%

Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

et al. 2010

View full text Add to dashboard Cite

show abstract

“…These results con®rm a previous report on biochemical markers of bone turnover in danish women (age: 29 ±53 y) (Overgaard et al, 1988). Interestingly, 40 ±72 y old chinese women living in a subtropical region showed high serum 25OHD levels (Tsai et al, 1997). Similar to our study, there was no correlation between 25OHD levels and markers of bone formation (PICP, bone speci®c alkaline phosphatase, osteocalcin) or bone resorption markers (Nterminal crosslinked fragment of type I collagen).…”

Section: Vitamin D Status and Calcium Absorptionsupporting

confidence: 90%

“…As con®rmed in previous studies (Need et al, 1993;DawsonHughes et al, 1997;Tsai et al, 1997) such a design can be used to reliably evaluate seasonal variations. Prerequisite is a similar pattern of decisive factors like age, body mass index, use of oral contraceptiva and endogeneous estrogen status in the populations.…”

Section: Discussionmentioning

confidence: 85%

Seasonal variations in vitamin D status and calcium absorption do not influence bone turnover in young women

1998

View full text Add to dashboard Cite

Objective: To evaluate the effect of seasonal variations in UV B-exposure on calcium absorption and bone turnover in young women with the overall goal to assess the potential bene®t of a vitamin D supplementation during wintertime. Design: Cross-sectional study. Setting: Area of Bonn, Germany (51 N). Subjects: Thirty-eight women (24.5 AE 0.5 y) studied in winter and 38 females of the same age (24.7 AE 0.4 y) studied in summer. Results: As estimated by a 4 d food record, both groups had similar dietary calcium and phosphorus intakes (b1200 mgad, respectively) covering actual recommendations. Signi®cant reductions in serum concentrations of 25-hydroxyvitamin D (25OHD) and calcitriol, fractional calcium absorption (Fc 220 , measured by means of a stable strontium test), 24 h urinary calcium and 24 h urinary phosphorus excretion were observed during wintertime. 25OHD but not calcitriol was correlated with Fc 220 values and with 24 h urinary phosphorus excretion. Moreover, Fc 220 was related to 24 h urinary calcium excretion. Fasting 2 h-urinary deoxypyridinoline concentrations (biomarker of bone resorption) and serum levels of carboxyterminal propeptide of type I procollagen (biomarker of bone formation) showed no differences between summer and winter. Conclusions: Our data indicate a decrease in intestinal calcium and phosphorus absorption during wintertime, most likely because of a reduction in serum 25OHD levels. Since bone turnover was not affected by the seasonal differences in mineral metabolism, there is no objective for young women with high calcium intake to supplement vitamin D during wintertime.

show abstract

“…Seasonal variation of bone mineral density, bone mineral content and bone size Earlier studies have reported seasonal variation in bone mass in different populations (Bergstralh et al 1990;Dawson-Hughes & Harris, 1993;Rosen et al 1994;Rapuri et al 2002) but others have not found such a variation (Vanderschueren et al 1991;Tsai et al 1997;Overgaard et al 1998). We stated a 7·5 -8·2 % seasonal variation in site-specific BMD in early puberty girls, which seems to be somewhat higher than observed in healthy adults (Bergstralh et al 1990;Dawson-Hughes & Harris, 1993).…”

Section: Seasonal Variation In Serum 25-hydroxyvitamin D and Parathyrcontrasting

confidence: 52%

A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls – a cross-sectional study

Viljakainen

Palssa

Kärkkäinen

et al. 2006

BJN

View full text Add to dashboard Cite

The importance of the seasonal variation of calcitropic hormones to growing skeleton has not been established. We studied whether there exists a seasonal variation in calcitropic hormones, bone mineral density (BMD) and bone remodelling markers in early puberty girls. One hundred and ninety-six girls, mean age 11·4 (SD 0·4) years, in Tanner stage 2 (early puberty) and 3 (mid-puberty) were studied during September to March. The BMD was measured from the lumbar vertebrae and the left femur by dual-energy X-ray absoptiometry. Their serum 25-hydroxyvitamin D (S-25-OHD), serum intact parathyroid hormone (S-iPTH), serum osteocalcin, urinary pyridinoline and urinary deoxypyridinoline were analysed from fasting samples. The concentration of S-25-OHD and serum osteocalcin differed among months (P, 0·01), reflecting a seasonal variation. The parathyroid hormone correlated negatively with S-25-OHD (r 2 0·325, P,0·001). Moreover, the BMD in the femur (P¼0·047) and to a lesser extent in vertebrae (P¼ 0·057) differed between months in early puberty girls but this was not seen in mid-puberty. Seasonal variation in S-25-OHD and bone remodelling markers accompanied by negative correlation between S-25-OHD and S-iPTH was seen in this cross-sectional study of adolescent girls. In addition, the seasonal rhythm contributed 7·0 -7·6 % difference in the BMD of lumbar vertebrae and left femur in early puberty girls. This variation should be avoided since it could hamper peak bone mass attainment.Seasonal variation: 25-Hydroxyvitamin D: Bone mineral density: Bone remodelling markers: Adolescent girls: Cross-sectional study Seasonal variation in serum 25-hydroxyvitamin D (S-25-OHD) and other calcitropic hormones is believed to determine the seasonal variation of bone mass (Krall et al. 1989;Dawson-Hughes & Harris, 1993). In healthy adults, the seasonal variation in bone mass is shown to be around 2 % (Bergstralh et al. 1990) whereas in the elderly it comprises 6 -8 % change (Rapuri et al. 2002;Bhattoa et al. 2004). Furthermore, a prospective communitybased study demonstrated that the rate of bone fractures and falls follow this seasonal periodicity (Pasco et al. 2004). Similar findings have been reported before (e.g. Jacobsen et al. 1991) in retrospective studies. Hence, this problem faces many, but the seasonality of bone mineral density (BMD) in adolescence has not been established.Bone growth accelerates at puberty. Any nutrient deficiency during this highly sensitive period could compromise the peak bone mass attainment and increase the risk of osteoporosis later in life (Matkovic et al. 1994). The importance of vitamin D during growth is evident (DeLuca, 1979). Furthermore, vitamin D is thought to limit bone mineral accretion (e.g. Lehtonen-Veromaa et al. 2002), as vitamin D insufficiency is commonly seen among adolescents (Vieth et al. 2001;Gordon et al. 2004;Andersen et al. 2005).Thus, the aim of the present study was to define the existence of seasonal variation in calcitropic hormones, sitespecific BMD and biochemical markers of...

show abstract

Vitamin D stores of urban women in Taipei: Effect on bone density and bone turnover, and seasonal variation

Cited by 44 publications

References 30 publications

Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

Seasonal variations in vitamin D status and calcium absorption do not influence bone turnover in young women

A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls – a cross-sectional study

Contact Info

Product

Resources

About