Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

Ardawi, M. S. M.; Qari, Mohammed H.; Rouzi, Abdulrahim A.; Maimani, A. A.; Raddadi, R.M.

doi:10.1007/s00198-010-1249-7

Cited by 141 publications

(144 citation statements)

References 74 publications

(100 reference statements)

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“…20 Similarly, the same authors in another study reported a prevalence of vitamin D deficiency among Saudi women of 80%, 21 which is lower compared with our figure (98%). Our higher prevalence might be attributed to the fact that our sample is clinic-based, compared with their community-based sample.…”

Section: Discussioncontrasting

confidence: 48%

Comparison of vitamin D deficiency in Saudi married couples

2012

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BACKGROUND/OBJECTIVE: Vitamin D deficiency is highly prevalent in Saudi Arabia. The study objective was to compare vitamin D deficiency in Saudi married couples. SUBJECTS/METHODS: This cross-sectional study was carried out in the Royal Guard primary health care center in Riyadh, Saudi Arabia on a consecutive sample of 50 Saudi married couples attending the center without complaints related to vitamin D deficiency. Data were collected through an interview questionnaire addressing the risk factors and dietary habits. Quantitative determination of total 25-hydroxy vitamin D in blood was done by Electro-Chemical Luminescence assay. Fieldwork was carried out from December 2010 to January 2011. RESULTS: Men had higher sun exposure (P ¼ 0.001), more use of light clothes at home (P ¼ 0.002) and more intake of milk (P ¼ 0.023) and soft drinks (P ¼ 0.001). Vitamin D was higher in men with mean difference about 9 nmol/l (Po0.001). The prevalence of vitamin D deficiency (o25 nmol/l) was 70% in women, compared with 40% in men (P ¼ 0.001). Multivariate analysis identified male gender, physical activity and the intake of milk as statistically significant positive independent predictors of vitamin D level, adjusted for factors as age, sun exposure, clothing, skin color, BMI, soft drinks and animal protein intake. CONCLUSION: Vitamin D deficiency is very high among Saudi married couples, especially wives. Female gender is an independent predictor of lower vitamin D level, in addition to sedentary lifestyle and low milk consumption. There is a need to revise the levels set for the diagnosis of vitamin D deficiency or insufficiency in the study region.

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Section: Discussioncontrasting

confidence: 48%

Comparison of vitamin D deficiency in Saudi married couples

2012

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“…A moderate positive correlation of25(OH)D with BMD measured by DEXA was found as 50% of subjects with hypovitaminosis D had low BMD. 31.8% of them were osteopenicand 18.1%had osteoprosis.These findings cope with the results of Bacon etal (40) ,Arabietal (41) ,Ardawietal (42) .Multiple regression analysis revealed that sun exposure was the main determiningfactore for 25(OH)D status.…”

Section: Discussionsupporting

confidence: 81%

Assessment of Vitamin D status among senior executive managers in large scale industries in the 10th of Ramadan city, Egypt

Im¹

2013

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“…Another study reported that VD deficiency was highly prevalent among studied Saudi women who suffer from obesity, poor sunlight exposure and poor dietary VD supplementation [27]. In our study, the significant low level of VD compared to normal BMI controls can be explained by several mechanisms.…”

Section: Discussionsupporting

confidence: 46%

Low Vitamin D Serum Levels May Be a Modifiable Risk Factor for Obesity and Cognitive Impairment in Middle-Age Egyptian Women

2014

Maced J Med Sci

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SUBJECTS AND METHODS:This study included 2 groups, Group-1(cases) consists of 120 obese females and Group-2 (controls) consists of 30 non-obese females. The included females were subjected to full clinical examination, anthropometric measurements and Kendrick Battery for evaluation of cognitive functions (short term memory and attention). Evaluation of serum Vitamin D, Parathyroid hormone, C-peptide and fasting blood glucose were done. The obese group was put on a balanced low caloric diet (900-1000 K Calories/day) for 2 months, where reevaluation was performed. RESULTS:Comparing obese group with non-obese control group revealed significant lower mean level of serum vitamin D associated with significant lower cognitive functions test and higher fasting blood glucose. After 2 months of low caloric diet, a significant increase in the serum level of vitamin D, accompanied with improvement in cognitive functions and decrease in fasting blood glucose and improved insulin resistance was seen. A correlation is found between vitamin D serum level and cognitive functions.CONCLUSION: A lower vitamin D serum level could be a modifiable risk factor for obesity, insulin resistance and cognitive impairment in middle age females.

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Vitamin D status in relation to obesity, bone mineral density, bone turnover markers and vitamin D receptor genotypes in healthy Saudi pre- and postmenopausal women

Abstract: Vitamin D deficiency is highly prevalent among healthy Saudi pre-and postmenopausal women and largely attributed to obesity, poor exposure to sunlight, poor dietary vitamin D supplementation, and age.

Cited by 141 publications

References 74 publications

Comparison of vitamin D deficiency in Saudi married couples

Comparison of vitamin D deficiency in Saudi married couples

Assessment of Vitamin D status among senior executive managers in large scale industries in the 10th of Ramadan city, Egypt

Low Vitamin D Serum Levels May Be a Modifiable Risk Factor for Obesity and Cognitive Impairment in Middle-Age Egyptian Women

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