Vitamin D Levels In Children with Bronchial Asthma

Somashekar, A. R.; Prithvi, Ashwini; Gowda, None Mahesh

doi:10.7860/jcdr/2014/10387.5055

Cited by 18 publications

(19 citation statements)

References 24 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar results were found in studies conducted with adolescents and adults [20]. A cross sectional study, including healthy and asthmatic children, reported that serum vitamin D levels were significantly lower in asthmatic children which positively correlated with forced expiratory volume in 1 second (FEV 1 ) [21]. …”

Section: Vitamin D and Asthmasupporting

confidence: 78%

The impact of vitamin D on asthmatic human airway smooth muscle

Hall

Fischer

Agrawal

2015

Expert Review of Respiratory Medicine

View full text Add to dashboard Cite

Asthma is a chronic heterogeneous disorder, which involves airway inflammation, airway hyperresponsiveness (AHR) and airway remodeling. The airway smooth muscle (ASM) bundle regulates the broncho-motor tone and plays a critical role in AHR as well as orchestrating inflammation. Vitamin D deficiency has been linked to increased severity and exacerbations of symptoms in asthmatic patients. It has been shown to modulate both immune and structural cells, including ASM cells, in inflammatory diseases. Given that current asthma therapies have not been successful in reversing airway remodeling, vitamin D supplementation as a potential therapeutic option has gained a great deal of attention. Here, we highlight the potential immunomodulatory properties of vitamin D in regulating ASM function and airway inflammation in bronchial asthma.

show abstract

Section: Vitamin D and Asthmasupporting

confidence: 78%

The impact of vitamin D on asthmatic human airway smooth muscle

Hall

Fischer

Agrawal

2015

Expert Review of Respiratory Medicine

View full text Add to dashboard Cite

show abstract

“…5 A study evaluating vitamin D levels in bronchial asthma cases in 44 children (Bangalore, India) revealed similar findings with majority of controls (84%) having insufficiency of vitamin D and there were neither controls nor cases with sufficient vitamin D levels. 8 A preliminary study conducted by Goswami et al on 25-hydroxyvitamin D concentrations in apparently healthy subjects in Delhi (India) revealed significant hypovitaminosis D in 90% cases. 9 Since then several researchers has substantiated the finding of low vitamin D levels and widespread vitamin D deficiency in all age groups including toddlers, school children, adult males and females residing both rural and urban areas.…”

Section: Discussionmentioning

confidence: 97%

Vitamin D deficiency among pediatric osteoarticular tuberculosis patients

Dabla

Agarwal

Mishra

et al. 2016

Journal of Clinical Orthopaedics and Trauma

View full text Add to dashboard Cite

show abstract

“…Unexpectedly, we observed a trend toward decreased pulmonary function with vitamin D supplementation compared with PL. Although many observational studies have reported positive associations between 25(OH)D levels and pulmonary function in childhood asthmatics , few vitamin D intervention trials have assessed pulmonary function. In contrast to our observations, supplemental vitamin D has been found to increase the rate of FEV 1 change in adults including after asthma exacerbation .…”

Section: Discussionmentioning

confidence: 99%