Vitamin D level and its determinants among Sudanese Women: Does it matter in a sunshine African Country?

Husain, Nazik Elmalaika; Suliman, Ahmed Abdel Badie; Abdelrahman, Ismail; Bedri, Shahinaz; Musa, Rasha M; Osman, Hind E; Mustafa, Ayda Hussein Omer; Gafer, Nahla; Farah, Ehab; Satir, Ali Abdel; Ahmed, Mohamed H.; Osman, Mugtaba; Agaimy, Abbas

doi:10.4103/jfmpc.jfmpc_247_19

Cited by 12 publications

(11 citation statements)

References 29 publications

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“…This individual genetic diversity could play a central role in determining 25(OH)D levels ( 41 , 42 , 43 , 44 ). According to Nissen ( 45 ), who analyzed twenty-five different genetic variants in seven different genes, it was concluded that polymorphisms in the CYP2R1 and GC genes are associated with serum variations in the vitamin D. In this same perspective, Husain et al ( 46 ), who compared Americans with European and African ancestry with similar lifestyles and demographic conditions, demonstrated that those with African ancestry had lower 25(OH)D values. Both studies suggest that specific ethnic and genetic determinants may influence vitamin D levels.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D and PTH: data from a cross-sectional study in an equatorial population

Queiroz¹,

Melo²,

Resende³

et al. 2020

Endocrine Connections

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Objective: Investigate the prevalence of vitamin D deficiency in an equatorial population through a large-sample study. Methods: Cross-sectional study with 30,224 healthy individuals from the North Region, in Brazil (Amazônia, state of Pará), who had 25-hydroxy-vitamin D (25(OH)D) and intact parathyroid hormone (PTH) serum levels measured by immunoassay method. Those with history of acute or chronic diseases were excluded. Abnormal levels of calcium, creatinine, glycemia and albumin were also exclusion criteria. Results: 25(OH)D levels were 29.1 ± 8.2ng/mL and values <12.7 ng/mL were equal to < -2 SD below average. Hypovitaminosis D was present in 10% of subjects according to the Institute of Medicine (values <20ng/mL) and in 59%, in consonance with Endocrine Society criteria (values 20-30 ng/mL as insufficiency and <20 ng/mL as deficiency). Individuals were divided according to four age brackets: children, adolescents, adults and elderly, and their 25(OH)D levels were: 33±9; 28,5±7,4; 28.3±7,7; 29.3±8,5ng/mL, respectively. All groups differed in 25(OH)D, except adolescents vs adults. Regression model showed BMI, sex, living zone (urban or rural) and age as independent variables to 25(OH)D levels. Comparing subjects with vitamin D deficiency (<20 ng/mL) to those with vitamin D insufficiency (20-30 ng/mL), a difference between PTH levels in these two groups was observed (95.9 ± 24.7pg/mL vs 44.2 ± 64.5pg/mL; p<0.01). Additionally, the most accurate predictive vitamin D level for subclinical hyperparathyroidism in ROC curve was 26ng/mL. Conclusion: Our equatorial population showed low prevalence of vitamin D hypovitaminosis ranging with age bracket. The insufficient category by Endocrine Society was corroborated by our PTH data.

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Section: Discussionmentioning

confidence: 99%

Vitamin D and PTH: data from a cross-sectional study in an equatorial population

Queiroz¹,

Melo²,

Resende³

et al. 2020

Endocrine Connections

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“…While nutritional insu ciency was reported by (40%) of the participants as a possible cause of vitamin D de ciency, no signi cant associations were found between participants' consumption of different vitamin D rich foods and their beliefs. However, their reported consumption of vitamin D rich food was better than the reported rates in a Sudanese study (27) which might contribute to the lower prevalence of vitamin D de ciency among Jordanian women than Sudanese women (28).…”

Section: Knowledge Scorementioning

confidence: 74%

Students’ ”D”ILEMMA: An Assessment of Knowledge, Attitudes and Practice Toward Vitamin D Among University Students

Mohamed

Al‐Qerem

Gassar

et al. 2020

Preprint

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Background: The message delivered to the public regarding vitamin D is unclear, and contradictory; particularly regarding sun exposure; previous studies in Jordan have revealed high prevalence of low vitamin D among university students. The aim of this study was to investigate university students’ knowledge, attitudes and practice regarding vitamin D.Method: A web-based cross-sectional survey completed by students at a Jordanian university in 2019. Binary logistic regression analysis was used to predict supplement use.Results: 496 students completed the questionnaire. The mean knowledge score was 31.3 (± 11.3) out of 100. Women had significantly higher beliefs that vitamin D deficiency is an escalating health issue (p<0.01). Negative practices regarding sun exposure was significantly higher in women than men (p<0.01). The majority of participants recognized that insufficient sun exposure was a cause of vitamin D deficiency, but 50.7 % avoid sun exposure, and 67.6% expose only their face and hands. The consumption of fortified foods (OR 3.59-;p<0.001) was the only studied variable associated with vitamin D consumption.Conclusion: There is a gap between knowledge, attitude, and practice regarding vitamin D which can be bridged by promoting Vitamin D related awareness.

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“…Acne vulgaris is a multifactorial chronic inflammatory disorder of the pilosebaceous follicles of human skin [3]. Recent studies in Sudan revealed a higher percentage of Vitamin D deficiency among women in Sudan [15]; this may be attributed to nutritional, skin color, sun exposure times, and uses of sun blockers.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D Deficiency among Females with Acne Vulgaris in Relation to Sun Exposure: A Cross-sectional Study

Elfadil

Mohammed

Elmugadam

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Acne vulgaris is a common chronic inflammatory disease of the skin. Vitamin D deficiency has been implicated in various skin diseases, including atopic dermatitis and psoriasis. AIM: The aim of this study was to evaluate the serum 25-hydroxy Vitamin D levels among patients with acne vulgaris. METHODS: This was a cross-sectional comparative study performed in Khartoum state at Military hospital, department of dermatology and venerology, 111 blood samples were collected from females to measure serum level of 25-hydroxy Vitamin D by immunoassay analyzer cobas-e-411-2ed generation platform of Electrochemiluminescence binding assay. RESULTS: In this study, 111 females their age 18–36 years. 57 suffering from acne vulgaris, 61.4% of them had moderate grade of acne. A significant decrease in the serum 25-hydroxy Vitamin D concentrations in acne vulgaris patients when compared to 54 non-acne group (13.3 ± 5.0 ng/mL vs. 24.2 ± 10.3 ng/mL p =0.00). Significant positive correlation between serum 25-OH Vitamin D and exposure to sunlight per day (r = 0.562, p = 0.00), while there was a significant negative correlation between 25-OH Vitamin D and grade of acne, and duration of disease per month (for grade of acne r = –0.641, p = 0.00), (for duration of disease r = –0.696, p = 0.00) among patients with acne vulgaris. CONCLUSION: The evidence from this study suggests that female with low serum 25- OH Vitamin D had increase risk to develop acne vulgaris. Further studies are needed to confirm this potential relation.

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Vitamin D level and its determinants among Sudanese Women: Does it matter in a sunshine African Country?

Cited by 12 publications

References 29 publications

Vitamin D and PTH: data from a cross-sectional study in an equatorial population

Vitamin D and PTH: data from a cross-sectional study in an equatorial population

Students’ ”D”ILEMMA: An Assessment of Knowledge, Attitudes and Practice Toward Vitamin D Among University Students

Vitamin D Deficiency among Females with Acne Vulgaris in Relation to Sun Exposure: A Cross-sectional Study

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