Vitamin D Deficiency in Children with Inflammatory Bowel Disease

Abstract

A high proportion of these Australian children with IBD were vitamin D deficient. This emphasizes the importance of monitoring vitamin D status, and treating deficiency, in the management of pediatric IBD. The possible benefit of nutritional therapy in protection against vitamin D deficiency requires further prospective study.

Hypovitaminosis D and Low Bone Mineral Density in Inflammatory Bowel Disease Patients

“…Data in the literature do not agree on the relationship between the ileal involvement in CD and deficiency of vitamin D. Some authors report an association between hypovitaminosis and ileal disease [21,29], while others did not find such correlation [19,25,30]. Our data are consistent with recent studies of Crohn's disease, demonstrating on the contrary a positive trend between hypovitaminosis and the extent of disease in ulcerative colitis.…”

“…The literature highlights an association between hypovitaminosis D and disease activity in IBD expressed in terms of clinical score of disease activity and/or alteration of biochemical markers [21,22]. This correlation appears to be stronger for CD than for UC [23,24].…”

Low Serum Vitamin D Levels in Egyptian Adults With Chronic Primary Immune Thrombocytopenia: A Single Center Study.

“…D'Aurizio et al [34] found that low serum levels of vitamin D did not correlate with Hashimoto's thyroiditis or with Grave's disease activity. Also, no correlation between vitamin D levels and disease activity was observed in a crosssectional study conducted by Levin et al [35] on children with inflammatory bowel diseases.…”

Exclusive enteral nutrition and induction of remission of active Crohn’s disease in children

“…Most common are iron and vitamin D deficiency [9]. Less commonly, deficiencies in www.expert-reviews.com Review other fat soluble vitamins, vitamin B12, zinc and selenium are observed [3].…”

“…A further study evaluated the impact of EEN upon vitamin D, an important contributor to bone health [9]. Vitamin D levels were assessed retrospectively in 78 children with CD.…”