Vitamin-C-Induced Hyperoxaluria

Harris, A. N. A.

doi:10.1016/s0140-6736(76)90125-2

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Acquired Oxalosis1

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1976

2012

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Cited by 6 publications

(1 citation statement)

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“…It is assumed that the severity of the deficiency required for hyperoxaluria to develop is greater than that required for the clinical manifestations. Recently, hyperoxaluria associated with raised vitamin C intake has been described (Briggs, 1976;Harris, 1976). Each of these states involving vitamin abnormalities must always be considered in oxalosis of otherwise obscure pathogenesis.…”

Section: Acquired Oxalosismentioning

confidence: 99%

Histopathological occurrence and characterisation of calcium oxalate: a review.

Chaplin¹

1977

J Clin Pathol

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Section: Acquired Oxalosismentioning

confidence: 99%

Histopathological occurrence and characterisation of calcium oxalate: a review.

Chaplin¹

1977

J Clin Pathol

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Safety of Antioxidant Vitamins

Meyers

Maloley²,

Weeks³

1996

Arch Intern Med

116

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As a result of the many scientific and popular press reports of the benefits of antioxidant vitamins (vitamin A, beta-carotene, vitamin E, and ascorbic acid), it is estimated that 40% of the US population is consuming vitamin supplements. The efficacy of these supplements is not yet proved, and some have questioned their safety. Approximately 10 to 15 cases of vitamin A toxic reactions are reported per year in the United States, usually at doses greater than 100,000 IU/d. No adverse effects have been reported for beta-carotene. The frequency of vitamin E toxic reactions is not well delineated, but case reports are few at dosages less than 3200 mg/d. Ascorbic acid toxic reactions are rare at dosages less than 4 g/d. Despite a lack of clinical trial data, it seems that antioxidant vitamins are safe, although prudence might dictate their avoidance by women of childbearing potential, persons with liver disease or renal dysfunction, and those taking certain medications or undergoing specific laboratory tests.

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What’s New — Vitamins and Minerals

Avioli¹

1976

The Year in Metabolism 1975–1976

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Vitamin-C-Induced Hyperoxaluria

Cited by 6 publications

References 2 publications

Histopathological occurrence and characterisation of calcium oxalate: a review.

Histopathological occurrence and characterisation of calcium oxalate: a review.

Safety of Antioxidant Vitamins

What’s New — Vitamins and Minerals

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