Vitamin B12 levels in patients with chronic telogen effluvium.

Çifci, Nurşad

doi:10.5505/ktd.2019.54871

Cited by 2 publications

(3 citation statements)

References 3 publications

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“…The number of patients with the highest abnormalities in all parameters was observed in TE and females; therefore, we particularly suggest examining patients with TE and female patients first. More studies had been reported on laboratory abnormalities in TE, and they may also support our suggestion [ 12 , 17 , 17 , 27 – 29 ]. After vitamin D deficiency in both sexes, investigation ferritin and hemoglobin deficiency in females and vitamin B12 deficiency in males may be recommended.…”

Section: Discussonsupporting

confidence: 90%

“…Vitamin B12 is suggested to have a role in hair follicle proliferation, as it is essential for DNA synthesis [ 17 – 18 ]. 2 However, there is still no sufficient data to recommend supplementation of vitamin B12 in TE, AGA, and AA [ 1 ].…”

Section: Discussonmentioning

confidence: 99%

“…2 However, there is still no sufficient data to recommend supplementation of vitamin B12 in TE, AGA, and AA [ 1 ]. In a case-control study examining vitamin B12 deficiency in women with TE, there was no difference between the groups in mean vitamin B12 levels, while the number of patients with vitamin B12 deficiency (11.9% vs. 6.7%) was significantly higher than controls [ 17 ]. In our study, mean vitamin B12 levels were not below the reference range in any group, and the highest number of patients with vitamin B12 deficiency was in the TE group (%20).…”

Section: Discussonmentioning

confidence: 99%

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Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Öner¹,

Akdeniz²

2021

Turk J Med Sci

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Background/aim: Vitamins and minerals are thought to play an essential but not entirely clear role in developing, preventing, and treating nonscarring alopecia. Telogen effluvium, androgenetic alopecia, and alopecia areata are the most common forms of nonscarring alopecias. We would like to present a different perspective on laboratory abnormalities in patients with nonscarring alopecia. Materials and methods:A total of 467 patients (287 females, 180 males) were included retrospectively. 160 patients in the telogen effluvium group, 101 patients in the androgenetic alopecia group, 99 patients in the alopecia areata group, and 107 patients in the hair loss group (patients who could not be diagnosed with any nonscarring alopecia and wanted to have an analysis due to the complaint of hair loss). Sociodemographic data, diagnostic distribution, and laboratory findings (hemoglobin, ferritin, vitamin B12, vitamin D, and TSH) were evaluated and compared. Results:The most common diagnosis was telogen effluvium in females and androgenetic alopecia in males. In women, hemoglobin (12.2% vs. 1.1%) and ferritin deficiencies (22.3% vs. 8.9%) were significantly higher than in men (p<0.001, p<0.001) Ferritin, hemoglobin, and vitamin B12 levels were significantly lower, and the number of patients with vitamin D, ferritin, hemoglobin and vitamin B12 deficiencies were significantly higher in the telogen effluvium group compared to the other groups. Laboratory abnormalities were detected least in the hair loss group.2 Conclusions:The number of patients with the highest abnormalities in all parameters was observed in the telogen effluvium group and females; therefore, we mainly suggest examining female patients with telogen effluvium first. We may prefer not to immediately investigate the laboratory abnormalities and follow up patients with some treatments in the hair loss group.

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Section: Discussonsupporting

confidence: 90%

Section: Discussonmentioning

confidence: 99%

Section: Discussonmentioning

confidence: 99%

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Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Öner¹,

Akdeniz²

2021

Turk J Med Sci

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A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels

Durusu Turkoglu,

Turkoglu,

Soylu

et al. 2024

J of Cosmetic Dermatology

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AimThe etiology of telogen effluvium (TE) includes situations that may cause physiological stress, surgical trauma, inflammatory, infectious, iatrogenic causes, medications and nutritional deficiencies. TE has been associated with iron deficiency, vitamin B12 deficiency and thyroid diseases. In recent years, the use of over‐the‐counter food supplements containing vitamins and minerals such as biotin, vitamin D, zinc (Zn), copper (Cu) and selenium (Se) has been increasing in TE patients. The aim of this study is to investigate whether there are differences in nutritional status, vitamin and mineral levels by comparing individuals with TE and a control group.Materials and MethodsThis case–control study included 90 female patients diagnosed with chronic telogen effluvium (CTE), and 90 female controls volunteered to participate in the study who consulted for reasons other than TE. Both groups aged 18 and over and applied to dermatology polyclinic between 01.09.2022 and 01.09.2023. A detailed anamnesis was taken from all patients, a hair pull test was performed, and TE was diagnosed after a dermoscopic examination was performed on all areas of the scalp. Then, serum vitamin D, Zn, Cu, Se levels and biotin levels in serum and urine were measured. Hemoglobin (Hb), ferritin, vitamin B12 and thyroid function tests were retrospectively scanned from the hospital database.ResultsIt was determined that Zn levels were significantly lower in CTE patients than in controls. Se levels were found to be significantly higher in patients than in controls. There was no difference in Hb, ferritin, vitamin B12, thyroid function tests, vitamin D, Cu levels, serum and urine biotin levels between the two groups. Zn, Cu/Zn and Se levels were found to have statistically significant diagnostic performance in predicting the diagnosis of CTE. Cu/Zn ratio and Se value were found to be significant predictors of CTE.ConclusionThis study shows us that nutritional deficiencies are not as common as thought in patients diagnosed with TE. Other causes that may cause TE should be investigated by a detailed anamnesis and a good physical examination. After all, tests for suspected conditions should be performed and individualized treatment options should be created for each patient.

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Vitamin B12 levels in patients with chronic telogen effluvium.

Cited by 2 publications

References 3 publications

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels

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