Vitality of Pro-Inflammatory Cytokine, Scavenger Receptor Proteins and Atherosclerotic Plaque Markers in Risk Prediction of Diabetic Nephropathy

Khot, Vinita; Yadav, K; Haldankar, V. A.; Bhutey, A. K.

doi:10.20546/ijcmas.2017.601.015

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2017

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“…CD36 is intimately involved in lipid metabolism and homoeostasis and has been strongly implicated in pathological conditions associated with metabolic dysregulation, including obesity, insulin resistance, diabetes, diabetic nephropathy and atherosclerosis. (2,19,25) Circulating form of CD36 was identified in human plasma as a novel biomarker for type 2 diabetes mellitus (T2DM) (24).Hyperglycaemia-induced synthesis of CD36 protein has been associated with increased uptake of LDL lead in atherosclerotic lesions in people with diabetes. (2,18).…”

Section: Resultsmentioning

confidence: 99%