Visual Outcome, Treatment Results, and Prognostic Factors in Patients with Scleritis

Incidence and Prevalence of Episcleritis and Scleritis in Northern California

“…Significantly higher rates of ocular complications and disease association were reported by Sainz de la Maza et al 5 Their study reported ocular complications in 19% of patients with episcleritis and 45% of patients with scleritis, including uveitis (16.5% and 26.4%, respectively). In the study by Wieringa et al, 7 88 patients (84.6%) had ocular complications indicating a high frequency of the occurrence of ocular complications associated with ocular inflammatory disease, such as scleritis. Similar to systemic disease associations, the rates of ocular complications in this study are likely less because of referral bias in the studies published before this one.…”

Granulomatosis with polyangiitis (Wegener's disease): An updated review of ocular disease manifestations

“…It is a common misconception that the presence of an ocular manifestation in the absence of systemic manifestations represents a quiet disease. It should be noticed that ocular manifestations, particularly necrotizing scleritis, can be an indicator for both morbidity and mortality unless appropriate systemic treatment is initiated (37,75).…”

Management with Nonsteroidal Anti-inflammatory Agents

“…With regard to the latter two points, the importance of a comprehensive clinical work-up for each of these patients cannot be overstated. Necessity, urgency, and safety of treatment are dependent upon these three points and are critically important in treatment success and prevention of ocular and drug-related complications [6,7]. Secondary points may include the relief of symptoms and the maintenance of quality of life for the patient, which can be bankrupt by inflammatory flare-ups [7].…”