Visual function and quality of life in pseudophakic patients before and after capsulotomy

Juan-Marcos, Lourdes de; Blanco-Blanco, Juan F.; Hernández-Galilea, Emiliano

doi:10.5301/ejo.5000146

Cited by 15 publications

(12 citation statements)

References 25 publications

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“…Although vision can readily be improved with neodymium:Yttrium‐Aluminum‐Garnet (Nd:YAG) laser discission of the opacified posterior capsule, PCO does have an impact on the patients’ quality of life during a period of time (de Juan‐Marcos et al. ; Yotsukura et al. ).…”

Section: Introductionmentioning

confidence: 99%

Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAGlaser treatments with two aspheric hydrophobic acrylic intraocular lenses – a long‐term intra‐individual study

Johansson

2017

Acta Ophthalmologica

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Section: Introductionmentioning

confidence: 99%

Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAGlaser treatments with two aspheric hydrophobic acrylic intraocular lenses – a long‐term intra‐individual study

Johansson

2017

Acta Ophthalmologica

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“…To complement objective VA information, it is now accepted that the evaluation of the impact of a disease on quality of life using a patient-reported outcome is important for medical interventions, therapeutic decisions, or outcomes research. De Juan-Marcos et al found that the VF-14 scores of patients correlate more strongly with their satisfaction with vision than VA, and VF-14 is more sensitive to functional disability caused by PCO and to capsulotomy improvements, however, improvement in VA is slightly correlated with gains in quality of life [5]. In our current study, regardless of baseline vision, the correspondence between OSI and VF-14 score is very high, while in patients with better baseline vision, the correlation between CDVA and VF-14 is poor.…”

Section: Discussionmentioning

confidence: 99%

“…If the item was not applicable or the subject was unable to complete due to other non-visual factors, the item was deleted and not used for scoring. The higher the score, the lighter the visual impairment [5].…”

Section: Study Design and Analysesmentioning

confidence: 99%

Utility of the optical quality analysis system for decision-making in Nd: YAG laser posterior capsulotomy in patients with light posterior capsule opacity

Lü

Zhu

Fan

et al. 2019

Preprint

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Background: To evaluate whether the Optical Quality Analysis System (OQAS) can serve as a valuable additional indicator for appropriate posterior capsulotomy referral. Methods: One hundred and five eyes from 96 patients undergoing capsulotomy were divided into precapsulotomy logMAR CDVA ≤ 0.1 group and logMAR CDVA > 0.1 group. CDVA， and the Visual Function 14 index (VF-14) score were estimated before and 1 month after capsulotomy. Objective scattering index (OSI) value was measured by using the OQAS. Posterior capsule opacification (PCO) severity was assessed with Evaluation of PCO 2000 (EPCO 2000) software. Results：In logMAR CDVA > 0.1 group, the correlations of OSI, logMAR CDVA, EPCO score and VF-14 score were very strong preoperatively. In logMAR CDVA ≤ 0.1 group, preoperatively, OSI was correlated with logMAR CDVA (r = 0.451), EPCO score (r = 0.789), and VF-14 score (r = 0.852). LogMAR CDVA has weak correlation with VF-14 score (r = -0.384) and EPCO score (r = 0.566). VF-14 score was correlated with EPCO score (r = -0.669). In the logMAR CDVA ≤ 0.1 group, there was no significant difference in logMAR CDVA between precapsulotomy and postcapsulotomy (P > 0.05). In the two groups, all the other optical quality parameters were significantly improved after capsulotomy (P < 0.05). Conclusions：The OSI was useful for the evaluation of PCO and prediction of beneficial capsulotomy. Especially for patients with slight PCO and better visual acuity, OSI is more valuable than CDVA and a complete objectivity examination. Trial registration: The study protocol was registered at the Chinese Clinical Trial Registry. Register: ChiCTR1800018842 (Registered Date: October 13th, 2018). Keywords: Posterior capsule opacification, Objective scattering index, Capsulotomy, Visual Function 14 index, Visual outcomes

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“…40,86,90,91,94,[101][102][103][104][105][106] The included studies were diverse in terms of their aims, comparisons made, study designs, patient characteristics and locations. The full data extraction forms for all included studies are provided (see Appendix 9).…”

Section: Systematic Review Of Health-related Quality-of-life Studiesmentioning

confidence: 99%

“…55 Other measures, such as contrast sensitivity and stereopsis, may be more important than visual acuity for functional tasks, especially in elderly people, 40,106 although they may be less straightforward to assess than visual acuity and may therefore require additional resources if routine tests are to be implemented in clinical practice. The RCTs suggested that stereopsis was more sensitive than visual acuity for indicating changes in vision following second-eye cataract surgery, although they did not indicate any major changes in contrast sensitivity.…”

Section: Other Relevant Factorsmentioning

confidence: 99%

The clinical effectiveness and cost-effectiveness of second-eye cataract surgery: a systematic review and economic evaluation

Frampton

Harris

Cooper

et al. 2014

Health Technology Assessment

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BackgroundElective cataract surgery is the most commonly performed surgical procedure in the NHS. In bilateral cataracts, the eye with greatest vision impairment from cataract is operated on first. First-eye surgery can improve vision and quality of life. However, it is unclear whether or not cataract surgery on the second eye provides enough incremental benefit to be considered clinically effective and cost-effective.ObjectiveTo conduct a systematic review of clinical effectiveness and analysis of cost-effectiveness of second-eye cataract surgery in England and Wales, based on an economic model informed by systematic reviews of cost-effectiveness and quality of life.Data sourcesTwelve electronic bibliographic databases, including MEDLINE, EMBASE, Web of Science, The Cochrane Library and the Centre for Reviews and Dissemination databases were searched from database inception to April 2013, with searches updated in July 2013. Reference lists of relevant publications were also checked and experts consulted.Review methodsTwo reviewers independently screened references, extracted and checked data from the included studies and appraised their risk of bias. Based on the review of cost-effectiveness, a de novo economic model was developed to estimate the cost-effectiveness of second-eye surgery in bilateral cataract patients. The model is based on changes in quality of life following second-eye surgery and includes post-surgical complications.ResultsThree randomised controlled trials (RCTs) of clinical effectiveness, three studies of cost-effectiveness and 10 studies of health-related quality of life (HRQoL) met the inclusion criteria for the systematic reviews and, where possible, were used to inform the economic analysis. Heterogeneity of studies precluded meta-analyses, and instead data were synthesised narratively. The RCTs assessed visual acuity, contrast sensitivity, stereopsis and several measures of HRQoL. Improvements in binocular visual acuity and contrast sensitivity were small and unlikely to be of clinical significance, but stereopsis was improved to a clinically meaningful extent following second-eye surgery. Studies did not provide evidence that second-eye surgery significantly affected HRQoL, apart from an improvement in the mental health component of HRQoL in one RCT. In the model, second-eye surgery generated 0.68 incremental quality-adjusted life-years with an incremental cost-effectiveness ratio of £1964. Model results were most sensitive to changes in the utility gain associated with second-eye surgery, but otherwise robust to changes in parameter values. The probability that second-eye surgery is cost-effective at willingness-to-pay thresholds of £10,000 and £20,000 is 100%.LimitationsClinical effectiveness studies were all conducted more than 9 years ago. Patients had good vision pre surgery which may not represent all patients eligible for second-eye surgery. For some vision-related patient-reported outcomes and HRQoL measures, thresholds for determining important clinical effects are either unclear or have not been determined.ConclusionsSecond-eye cataract surgery is generally cost-effective based on the best available data and under most assumptions. However, more up-to-date data are needed. A well-conducted RCT that reflects current populations and enables the estimation of health state utility values would be appropriate. Guidance is required on which vision-related, patient-reported outcomes are suitable for assessing effects of cataract surgery in the NHS and how these measures should be interpreted clinically.Study registrationThis project is registered as PROSPERO CRD42013004211.FundingThis project was funded by the National Institute for Health Research Health Technology Assessment programme.

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Visual function and quality of life in pseudophakic patients before and after capsulotomy

Cited by 15 publications

References 25 publications

Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAGlaser treatments with two aspheric hydrophobic acrylic intraocular lenses – a long‐term intra‐individual study

Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAGlaser treatments with two aspheric hydrophobic acrylic intraocular lenses – a long‐term intra‐individual study

Utility of the optical quality analysis system for decision-making in Nd: YAG laser posterior capsulotomy in patients with light posterior capsule opacity

The clinical effectiveness and cost-effectiveness of second-eye cataract surgery: a systematic review and economic evaluation

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