Glistenings, anterior/posterior capsular opacification and incidence of Nd:YAGlaser treatments with two aspheric hydrophobic acrylic intraocular lenses – a long‐term intra‐individual study
Abstract:Visual outcomes, PCO development over time and need for Nd:YAG laser treatment were similar for the two IOLs. Anterior capsule fibrosis/contraction and glistenings were more pronounced with the SN60WF IOL.
“…However, although a clear improvement can be seen for the SN60WF, the MA60AC IOLs showed that glistenings may still exist in other AcrySof lenses, also those manufactured after 2012 (De Soyza J, et al RANZCO 2017, Abstract number: S1902). 15,45 This problem may be resolved by the new Clareon material introduced by Alcon, which was shown to be glistenings-free in preclinical in vitro studies (Auffarth GU, ESCRS 2017).…”
We showed that hydrophobic-acrylic lenses differ in their resistance to glistenings, as one group proved to be glistening-free, but the other models revealed varying grades of glistenings. Moreover, we demonstrated that the presence of glistenings results in increased straylight, and that straylight proportionally depends on the glistenings number irrespective of the IOL model. However, more research is needed to confirm that the relationship we found holds for all hydrophobic-acrylic IOLs.
“…However, although a clear improvement can be seen for the SN60WF, the MA60AC IOLs showed that glistenings may still exist in other AcrySof lenses, also those manufactured after 2012 (De Soyza J, et al RANZCO 2017, Abstract number: S1902). 15,45 This problem may be resolved by the new Clareon material introduced by Alcon, which was shown to be glistenings-free in preclinical in vitro studies (Auffarth GU, ESCRS 2017).…”
We showed that hydrophobic-acrylic lenses differ in their resistance to glistenings, as one group proved to be glistening-free, but the other models revealed varying grades of glistenings. Moreover, we demonstrated that the presence of glistenings results in increased straylight, and that straylight proportionally depends on the glistenings number irrespective of the IOL model. However, more research is needed to confirm that the relationship we found holds for all hydrophobic-acrylic IOLs.
“…Ton Van et al and Johansson et al reported the 3-year cumulative incidence of PCO requiring Nd:YAG laser capsulotomy, ie, 2.2% and 10.0%, respectively. 4 , 5 However, Baratz et al reported 6% at 1 year, which increased to 38% at 9 years. 6 …”
Section: Discussionmentioning
confidence: 98%
“…Teshigawara et al capsulotomy, ie, 2.2% and 10.0%, respectively. 4,5 However, Baratz et al reported 6% at 1 year, which increased to 38% at 9 years. 6 Nd:YAG laser treatment is a generally safe method to relieve the symptoms of PCO, such as reduction in visual acuity, haze, and glare.…”
Posterior capsule opacification (PCO) is the most common cause of deterioration of vision and contrast sensitivity and glare after cataract surgery. Neodymium (Nd): yttrium aluminum garnet (YAG) laser capsulotomy is an effective and standard procedure to treat these symptoms. The incidence rate of PCO requiring Nd:YAG laser treatment varies and depends on published studies, ranging from 2.2% to 10.0%. Although Nd:YAG laser treatment is largely safe, it still has complications, such as transient increase of intraocular pressure, anterior uveitis, intraocular lenses pitting, cystoid macula edema, endophthalmitis, and retinal detachment. We encountered a rare complication related to Nd:YAG laser treatment, where the laser accidentally hits the cornea. This occurred because the PCO was mistaken for the corneal layers during the laser procedure. This report presents the 3-year post-treatment process, and the findings herein may help raise the awareness of the possibility of this rare complication and provide measures for its treatment.
“…The most frequent postoperative complication of a successfully performed cataract surgery is the development of posterior capsule opacification (PCO), also known as the secondary cataract [4] (Figure1). It could provoke the decrease of the best-corrected visual acuity, reduction of contrast sensitivity, glare occurrence, or monocular diplopia [4]. PCO is caused by proliferation and migration of the remaining residual epithelial cells.…”
Section: The Effect Of Intraocular Lens Materials and Postoperative Thmentioning
Introduction/Objective The most frequent postoperative complication of a successfully performed phacoemulsification cataract surgery is the development of posterior capsule opacification (PCO). It is caused by the proliferation and migration of the remaining residual epithelial cells. The objective of this study was to investigate the influence of two different intraocular lenses and two different anti-inflammatory drugs on the development of PCO in one-year follow-up period. Methods Investigation included 120 patients (120 eyes), equally divided into four groups. The first two groups included patients who used non-steroid anti-inflammatory drug (NSAID) postoperatively, while the other groups had corticosteroid therapy. The first and third group got hydrophilic intraocular lenses (IOL), the second and fourth group had hydrophobic IOL. Software program EPCO 2000 was used for the analysis of PCO. Student's t-test, Wilcoxon test, and ANOVA were used for data analysis and p < 0.05 value was accepted as statistically significant. Results After the first three postoperative months, patients from NSAID groups had mean PCO score 0.25 ± 0.03, which was statistically significant higher (p = 0.042) comparing to corticosteroid groups. At the end of the investigation, the best result in PCO preventing was seen in the group of patients with hydrophobic IOL and corticosteroid therapy, with the mean PCO score of 0.47 ± 0.08. Conclusion This study has revealed that IOL made of acrylic hydrophobic material seemed to be the right choice when choosing intraocular lens to prevent PCO development. On the other hand, NSAID and corticosteroid therapy have showed similar results in preventing postoperative intraocular inflammation. This fact can be very useful in situations when corticosteroids must be used with great caution.
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