“…The risk of bias is shown in Figure 2 . Twelve studies reported random sequence generation [ 17 , 18 , 20 , 21 , 35 , 36 , 37 , 38 , 39 , 42 , 43 , 44 ], and twelve studies used the concealed allocation approach [ 17 , 18 , 20 , 21 , 35 , 36 , 37 , 38 , 39 , 42 , 43 , 44 ]. Only two studies designed the protocol in order that participants were blinded [ 38 , 42 ].…”