Visual and auditory contextual cues differentially influence alcohol-related inhibitory control

Qureshi, Adam; Monk, Rebecca; Pennington, Charlotte Rebecca; Oulton, Jennifer Rose

doi:10.31234/osf.io/p9gxn

Cited by 2 publications

(2 citation statements)

References 41 publications

(64 reference statements)

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“…According to this, the acetylcholine esterase (AchE) inhibitors may improve the frontal executive function in AUDs. Clinicians should also be cautious about the exposure of the social drinkers to the different types of alcohol-related stimuli during anti-saccade tasks, such as alcohol-related auditory cues ( 91 ).…”

Section: Limitations and Future Directionsmentioning

confidence: 99%

Anti-saccade as a Tool to Evaluate Neurocognitive Impairment in Alcohol Use Disorder

Wang

Zhao

2022

Front. Psychiatry

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It has been widely shown that chronic alcohol use leads to cognitive dysfunctions, especially inhibitory control. In an extension of the traditional approach, this research field has benefited from the emergence of innovative measures, among which is an anti-saccade, allowing direct and sensitive measure of the eye movements indexing attention bias to alcohol-related cues and the capability of inhibiting the reflexive saccades to the cues. During the past decade, there are numerous reports showing that drinkers make more unwanted reflexive saccades and longer latency in the anti-saccade task. These increased errors are usually explained by the deficits in inhibitory control. It has been demonstrated that inhibitory control on eye movement may be one of the earliest biomarkers of the onset of alcohol-related cognitive impairments. This review summarizes how an anti-saccade task can be used as a tool to investigate and assess the cognitive dysfunctions and the early detection of relapsing risk of alcohol dependence.

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Section: Limitations and Future Directionsmentioning

confidence: 99%

Anti-saccade as a Tool to Evaluate Neurocognitive Impairment in Alcohol Use Disorder

Wang

Zhao

2022

Front. Psychiatry

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“…Research investigating contextual influences on AUD has primarily focused on cue reactivity, which comprises automatic and subconscious reactions to specific alcohol-related stimuli, such as the sight, taste, or smell of an alcoholic beverage [19, 20]. The evidence supporting cue reactivity is multifaceted, and based on different types of assessments such as self-reports, as well as behavioural and neurophysiological measures.…”

Section: Introductionmentioning

confidence: 99%

Using Imagination to Integrate Contextual Effects in a Cue-Reactivity Paradigm in Patients with Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Pilot Study

et al. 2022

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Introduction: In individuals with alcohol use disorder (AUD), the brain areas underlying cue-induced reactions (e.g., cingulum, striatum, thalamus) and altered activation of these regions have been identified by functional neuroimaging. Neuronal responses to a complex alcohol-related context are yet to investigate. To better understand contextual effects as well as the interplay of cue-induced neural reactions and context exposure, the present study implemented an imagination procedure during functional magnetic resonance imaging (fMRI). Methods: Thirteen patients with AUD and 13 healthy controls completed two rounds of a cue-reactivity paradigm inside an MRI scanner. Two individualized imagination tasks were conducted before each of the two cue reactivity tasks. A 2 (group) × 2 (imagination) × 2 (picture-type) analysis of variance (ANOVA) was performed. Results: The ANOVA revealed a main effect for imagination with higher activation in bilateral thalamus and right caudate nucleus and an interaction effect between imagination and group in right thalamus and left caudate nucleus, due to the patient group reacting stronger during alcohol-related imagination. These structures are involved in relaying sensory information and habit learning. No main or interaction effects of picture type were observed. Conclusions: These results support the view that context effects alter the neural responses in thalamus and nucleus caudatus in patients with AUD, and that imagination tasks are suited to incorporate contextual influences in neurophysiological research designs. Future research needs to investigate whether the failure to observe a picture-type effect was due to limited statistical power and omission to individualize picture set, or whether an imagination procedure interferes with the evocation of picture-type effects.

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Visual and auditory contextual cues differentially influence alcohol-related inhibitory control

Cited by 2 publications

References 41 publications

Anti-saccade as a Tool to Evaluate Neurocognitive Impairment in Alcohol Use Disorder

Anti-saccade as a Tool to Evaluate Neurocognitive Impairment in Alcohol Use Disorder

Using Imagination to Integrate Contextual Effects in a Cue-Reactivity Paradigm in Patients with Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Pilot Study

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