Visceral Leishmaniasis (Kala-azar) in Iran: A Pathologic and Electron Microscopic Study

Daneshbod, Khosrow

doi:10.1093/ajcp/57.2.156

Cited by 45 publications

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“…Lipid droplets and ribosomes were in the cytoplasm of some organisms. The morphologic characteristics of these organisms were compatible with those described for Leishmania species [1][2][3][4]113. Large amounts of fibrillar material typical of amyloid were in and around plasma cells and near cells containing parasites ( fig.…”

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confidence: 61%

Canine Leishmaniasis with Amyloidosis

et al. 1976

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Abstract. Visceral leishmaniasis was diagnosed in a 2-year-old male Great Dane imported from Greece. The clinical signs included anemia, diarrhea, weight loss, proteinuria, and hyperglobulinemia with increases in a*-and y-regions. At necropsy there was plasmalymphocytic and macrophage infiltration of spleen, macrophage infiltration of bone marrow, intracellular organisms of macrophages having the ultrastructural characteristics of Leishmania species, and severe amyloidosis of the spleen, liver, and kidney.

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confidence: 61%

Canine Leishmaniasis with Amyloidosis

et al. 1976

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“…2 Glucantine is the first-choice treatment, and the side effects are few. [1][2][3][4] Cytoplasm of a typical Leishman body contains a nucleus and a kinetoplast. By electron microscope, a Leishman body shows a double-layer, tubular membrane encasing the organism, an oval nucleus with peripheral chromatin, a rod-shaped kinetoplast and a target-shaped basal body, and sometimes a segment of flagellum is visible.…”

Section: Discussionmentioning

confidence: 99%

“…By electron microscope, a Leishman body shows a double-layer, tubular membrane encasing the organism, an oval nucleus with peripheral chromatin, a rod-shaped kinetoplast and a target-shaped basal body, and sometimes a segment of flagellum is visible. 1,9,10 The complete form of LDB can be seen in aspiration of bone marrow, lymph node In this study 204 cases of bone marrow aspiration and 887 slides of documented cases of kala-azar were reviewed in order to find cytologic clues other than typical intrahistiocytic cytoplasmic and free LDBs.…”

Section: Discussionmentioning

confidence: 99%

“…In bone marrow smears, the parasites are oval-round bodies with large nuclei, 2 to 4 μm in diameter, and display the characteristic kinetoplast. 1,4 If Leishman-Donovan bodies (LDBs) are not seen in bone marrow examination, one could easily mistake kala-azar for tuberculosis (TB), brucellosis, viral or fungal infections. 2 In many of our case series the diagnosis was made only after review of smears by experts and molecular confirmation in selected cases.…”

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Bone Marrow Aspiration Findings in Kala-Azar

2010

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“…Fibrin-ring and epithelioid granulomas have also been described. 42,43 Enterobius vermicularis (Pinworms)…”

Section: Selected Examples Of Hepatic Parasitic Infections Featuring mentioning

confidence: 99%

Hepatic Granulomas: A Review With Emphasis on Infectious Causes

Lamps

2015

Archives of Pathology &Amp; Laboratory Medicine

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Context Many diseases that cause granulomas or granulomatous inflammation involve the liver. Some of these disease processes are intrinsic hepatic diseases, whereas others are disseminated systemic diseases that involve the liver as well as other organs. Objective To review the evaluation of granulomas in the liver with an emphasis on infectious causes, as well as the use of special stains, serologic studies, and molecular diagnostic techniques. Pertinent noninfectious causes of hepatic granulomas that are in the differential diagnosis are also discussed. Data Sources Literature review and cases acquired during years of practice. Conclusions A wide variety of infectious and noninfectious entities cause hepatic granulomas.

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Visceral Leishmaniasis (Kala-azar) in Iran: A Pathologic and Electron Microscopic Study

Cited by 45 publications

References 0 publications

Canine Leishmaniasis with Amyloidosis

Canine Leishmaniasis with Amyloidosis

Bone Marrow Aspiration Findings in Kala-Azar

Hepatic Granulomas: A Review With Emphasis on Infectious Causes

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