Visceral adiposity index (<scp>VAI</scp>) is related to the severity of anovulation and other clinical features in women with polycystic ovary syndrome

Androulakis, Ioannis I.; Kandaraki, Eleni; Christakou, Charikleia; Karachalios, Athanasios; Marinakis, Evangelos; Paterakis, Thomas; Diamanti-Kandarakis, Evanthia

doi:10.1111/cen.12447

Cited by 38 publications

(26 citation statements)

References 29 publications

(34 reference statements)

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“…The authors of the quoted study revealed significantly higher values of VAI and HOMA in the group of PCOS women with menstrual disorders versus the female group with normal ovulation. 7 In the research conducted by the authors of this manuscript, the studied women were not divided according to menstrual disorders.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of a new anthropometric indicator – VAI (Visceral Adiposity Index) in the evaluation of metabolic and hormonal disorders in women with polycystic ovary syndrome

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Usefulness of a new anthropometric indicator – VAI (Visceral Adiposity Index) in the evaluation of metabolic and hormonal disorders in women with polycystic ovary syndrome

et al. 2017

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“…17 In regression analysis, we found VAI was non-significant predictor of total testosterone levels in polycystic ovarian disease patients.…”

Section: Discussionmentioning

confidence: 76%

“…16 Hyperandrogenemia is the biochemical hallmark of PCOS. 17 Previous studies hypothesized that hyperinsulinemia causes hyperandrogenemia and anovulation in PCOS. 18 On the other hand other studies, since many normal-weight PCOS patients are not insulin resistant, the hypothesis that hyperandrogenism per se leads to abdominal visceral adiposity, insulin resistance and hyperinsulinemia has been postulated by many authors.…”

Section: Introductionmentioning

confidence: 99%

“…18 On the other hand other studies, since many normal-weight PCOS patients are not insulin resistant, the hypothesis that hyperandrogenism per se leads to abdominal visceral adiposity, insulin resistance and hyperinsulinemia has been postulated by many authors. 17 Visceral adiposity index is a marker of ATD and correlated with insulin resistance in PCOS. 13 Relation between VAI with hyperandrogenism and anovulation in PCOS is unclear.…”

Section: Introductionmentioning

confidence: 99%

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Visceral adiposity index correlation with Rotterdam criteria in patients with polycystic ovary syndrome

Aboelnaga

Elshahawy

2016

Int J Reprod Contracept Obstet Gynecol

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“…Hence the findings were not conclusive. 15 Since the sample size was very small, the results cannot be generalized. Studies with larger samples need to be undertaken to evaluate this proof of concept.…”

Section: Discussionmentioning

confidence: 99%

Visceral adiposity index among young girls with PCOS and its association with phenotypes and metabolic risk

Joshi¹,

Lakhan

Mukherji

et al. 2018

Int J Reprod Contracept Obstet Gynecol

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Background: Polycystic Ovarian Syndrome (PCOS) is a growing endocrine-metabolic disease in India. Visceral Adiposity Index (VAI) is a surrogate marker of visceral adipose dysfunction and can be used as a useful predictor of unhealthy PCOS phenotypes in low resource settings. No cut-off has been assessed among Indian population.Methods: Secondary data from 106 diagnosed girls with PCOS and 121 controls was analysed to estimate (i) VAI and BMI among different phenotypes (ii) risk of metabolic disorders using VAI among different phenotypes of PCOS and (iii) compare the overall diagnostic performance (for metabolic syndrome) of VAI, BMI and waist circumference.Results: Majority of the girls in the sample considered for analysis were lean PCOS (61%). Mean VAI among PCOS (3.02) was significantly higher than normal controls (2.81). Classic and Mild Phenotypes had high VAI. A unit increase in VAI score was found associated with 5.23 times higher risk of metabolic syndrome (AOR: 5.23, 95% CI: 2.261-12.086). A higher VAI with cut off value of 2.73 could predict risk of metabolic syndrome among PCOS cases, unlike the cutoff among Caucassian population of 1.67. The cut-off for the non- obese group was even higher i.e. 2.81.Conclusions: Given that Indians are genetically more prone to have excess visceral fat the cut-offs for measuring adiposity also needs to be re-defined. The findings of this small sample throws light on the prevalence of visceral adiposity among lean girls with PCOS emphasizing the need to also screen them for metabolic syndrome, educate them about these complications and motivate them to practice healthy lifestyles.

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Visceral adiposity index (VAI) is related to the severity of anovulation and other clinical features in women with polycystic ovary syndrome

Abstract: Visceral adiposity index is increased in patients with PCOS in concordance with the severity of anovulation, insulin resistance and inflammation. This index could be a very easy and helpful clinical tool in daily practice to predict insulin resistance in women with PCOS.

Cited by 38 publications

References 29 publications

Usefulness of a new anthropometric indicator – VAI (Visceral Adiposity Index) in the evaluation of metabolic and hormonal disorders in women with polycystic ovary syndrome

Usefulness of a new anthropometric indicator – VAI (Visceral Adiposity Index) in the evaluation of metabolic and hormonal disorders in women with polycystic ovary syndrome

Visceral adiposity index correlation with Rotterdam criteria in patients with polycystic ovary syndrome

Visceral adiposity index among young girls with PCOS and its association with phenotypes and metabolic risk

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