Visceral adipose tissue level, as estimated by the bioimpedance analysis method, is associated with impaired lung function

Abstract

Aims/Introduction: It has been reported that metabolic syndrome is associated with impaired lung function, and abdominal obesity is regarded as the most important determinant of this association. We evaluated the association between a component of metabolic syndrome, indices of body composition, including the total adipose tissue content, lean bodyweight and visceral adipose tissue content, as assessed by bioimpedance analysis, and lung function.Materials and Methods: A total of 516 participants responded to our questionnaire to determine the smoking status and history of past diseases. Waist circumference, height, bodyweight, percent forced expiratory volume in 1 s (%FEV1) and percent forced vital capacity (%FVC) were measured. Fasting blood samples were obtained to determine the serum levels of high‐density lipoprotein and triglyceride, and also the blood glucose. The body composition, including the total adipose tissue content and lean bodyweight, was measured, and the visceral adipose tissue content was estimated as the visceral adipose tissue level, by the bioimpedance analysis method.Results: Waist circumference, estimated visceral adipose tissue level and blood pressure were significantly associated with the %FEV1, and the serum high‐density lipoprotein cholesterol was significantly associated with the %FVC in men, after adjustment for age, smoking history, and past histories of bronchial asthma and ischemic heart disease. However, this association was not detected in women.Conclusions: We found an association between the visceral adipose tissue level as estimated by the bioimpedance analysis method and lung function. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2011.00189.x, 2011)

Relationship between Body Composition and Pulmonary Function in Early Adult Life: A Cross-Sectional Analysis Nested in Two Birth Cohort Studies

“…Previous studies also found an association of the distribution of FM on PF [ 5 , 6 , 14 , 25 , 29 , 32 – 39 ]. In the present study, WC was not linearly associated with PF at 18 and 30 years old.…”

Association of serum adiponectin with asthma and pulmonary function in the Japanese population

“…A total of 570 members from the general population of Fuchu town in Toyama, Japan, participated in a cohort study conducted in 2008, as previously reported (group 1) [27,28] (Fig. 1).…”

“…Murine studies have shown that the adiponectin-asthma association is bidirectional, whereby exogenous adiponectin attenuates airway changes in asthma and allergeninduced bronchoprovocation decreases adiponectin concentrations [5,6]. In humans, high levels of adiponectin have reportedly been associated with reduced odds of asthma in pre-menopausal and post-menopausal women in cross-sectional studies [7,8], and low serum previous study (group 1) [27,28], we compared the serum total adiponectin level between asthmatic subjects and non-asthmatic subjects and analyzed the association of the serum total adiponectin level with pulmonary function, including airway reversibility. Second, we enrolled another cohort (group 2) consisting of asthmatic subjects who regularly attended outpatient clinics and non-asthmatic subjects and compared the levels of total, HMW, MMW and LMW adiponectin and the ratio of each adiponectin isoform to the total adiponectin level between the asthmatic and non-asthmatic subjects.…”

Frequency of Exposure to Secondhand Smoke Outside the Home Is Associated with a Lower FEV₁/FVC in Male Workers Regardless of Smoking Status

“…Recent reports have indicated that smokers not only have increased abdominal obesity, but also decreased physical activity (PA) and poor nutritional balance [8][9][10][11][12]. In particular, abdominal obesity has been shown to be associated with decreased respiratory function, which is the subject of this study [13]. To the authorsʼ knowledge, however, no comprehensive previous studies have considered these variables.…”