Viruses with bisegmented double-stranded rna in pig faeces

Gatti, Maria Sílvia Viccari; Castro, Antonio Fernando Pestana de; Ferraz, Mirtis Maria Giaciani; Fialfio, A.M.; Pereira, H. G.

doi:10.1016/s0034-5288(18)31269-4

Cited by 48 publications

(44 citation statements)

References 6 publications

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“…Later, PBVs have been identified in faecal specimens of humans practically worldwide [3, 6, 7, 14, 26-29, 51, 55, 56, 61, 68, 76]. PBVs were also detected in faeces of a wide variety of farm mammals, birds, wild animals and birds kept in captivity, etc., viz., pigs [2,4,16,31,34,50,56,67], calves [10,15,35,53,54,61,77,79], rabbits and guinea pigs [25,43,52,65], bats [86], red fox [8], avian such as chickens & poults [1,49,59,69,73], and other wild animals kept in captivity like Giant Anteaters [45]; giant cats like Lion, Puma, Jaguar and Geoffroy's cat [37], sea lion [84], human primates such as Orangutan, wild birds such as American Ostrich, gloomy pheasant, Chinese goose [57], goat kids and lambs [60], donkeys [57,58], foals [9,30], laboratory non-human primates such as rhesus, pigtailed macaques and cynomolgus monkeys [83] and dogs [17,23,81], rats [23,64], snakes [23] and turkeys …”

Section: Discovery Of Picobirnavirusmentioning

confidence: 99%

“…In farm animals, the first report of the association of Picobirnavirus with disease came from a study involving pigs in an organized farm in Brazil [34]. These authors reported a higher proportion of PBV detection in animals with diarrhea than in those without diarrhea (15.3 vs 9.6 %).…”

Section: The Pathogenic Potentialmentioning

confidence: 99%

“…The virion is non-enveloped, small, spherical, 33-41 nm in diameter, with bisegmented dsRNA and consists of a simple core capsid with a distinctive icosahedral arrangement [21,63,68,82]. Based on the migration pattern of the bisegmented dsRNA, PBV appears either with large genome profile (2.3-2.6 kbp for the larger and 1.5-1.9 kbp for the smaller segment, respectively) [34,68] or small genome profile (1.75 and 1.55 kbp for segments 1 and 2, respectively) [6,26,27,34] in PAGE experiments.…”

Section: Introductionmentioning

confidence: 99%

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Animal Picobirnavirus

2014

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Picobirnavirus (PBV) is a small, non-enveloped, bisegmented double-stranded RNA (dsRNA) virus of vertebrate hosts. The name 'Picobirnavirus' derives from the prefix 'pico' (latin for 'small') in reference to the small virion size, plus the prefix 'bi' (latin for 'two') and the word 'RNA' to indicate the nature of the viral genome. The serendipitous discovery of PBV dates back to 1988 from Brazil, when human fecal samples collected during the acute gastroenteritis outbreaks were subjected for routine rotavirus surveillance by polyacrylamide gel electrophoresis (PAGE) and silver straining (S/S). The PAGE gels after silver staining showed a typical 'two RNA band' pattern, and it was identified as Picobirnavirus. Likewise, the feces of wild black-footed pigmy rice rats (Oryzomys nigripes) subjected for PAGE assay by the same research group in Brazil reported the presence of PBV (Pereira et al., J Gen Virol 69:2749-2754. PBVs have been detected in faeces of humans and wide range of animal species with or without diarrhoea, worldwide. The probable role of PBV as either a 'primary diarrhoeal agent' in 'immunocompetent children'; or a 'potential pathogen' in 'immunocompromised individuals' or an 'innocuous virus' in the intestine remains elusive and needs to be investigated despite the numerous reports of the presence of PBV in fecal samples of various species of domestic mammals, wild animals, birds and snakes; our current knowledge of their biology, etiology, pathogenicity or their transmission characteristics remains subtle. This review aims to analyse the veterinary and zoonotic aspects of animal Picobirnavirus infections since its discovery.

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Section: Discovery Of Picobirnavirusmentioning

confidence: 99%

Section: The Pathogenic Potentialmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Animal Picobirnavirus

2014

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“…The mean herd size was 180 animals for sheep and 40 fermenting colonies, with different morphology were subcultured onto the same agar. They were speciated using the API 20E system (Biomerieux, France) and stored at -80°C in nutrient broth with 30 % glycerol.…”

Section: Farmsmentioning

confidence: 99%

“…perfringens and Salmonella spp seem to have little or no role in diarrhoea in lambs. Picobirnaviruses have been isolated from cattle, horses and pigs [40,41], but their role in the pathogenicity of diarrhoea is unknown. In contrast, Cl.…”

Section: Clinical Characteristics Of the Outbreaksmentioning

confidence: 99%

Role of enteric pathogens in the aetiology of neonatal diarrhoea in lambs and goat kids in Spain

et al. 1996

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SUMMARYFaeces samples from diarrhoeic and non-diarrhoeic lambs and goat kids aged 1-45 days were examined for enteric pathogens. Cryptosporidium parvum was detected in both diarrhoeic lambs (45 %) and goat kids (42%) but not in non-diarrhoeic animals. F5+ (K99+) and/or F41+ Escherichia coli strains were isolated from 26% and 22 % of the diarrhoeic lambs and goat kids, respectively, although these strains, which did not produce enterotoxins ST I or LT I, were found with similar frequencies in non-diarrhoeic animals. A F5-F41 -ST I' E. coli strain was isolated from a diarrhoeic lamb (0-6%). Verotoxigenic E. coli was isolated from both diarrhoeic and non-diarrhoeic lambs (4-1 % and 8&2 %, respectively) and there was no association between infection and diarrhoea. The prevalence of group A rotavirus infection in diarrhoeic lambs was very low (2 1 %). Groups A and B rotaviruses were detected in three (8-1 %) and five (13-5 %) diarrhoeic goat kids from two single outbreaks. Group C rotaviruses were detected in four non-diarrhoeic goat kids. An association of diarrhoea and infection was demonstrated only for group B rotavirus. Clostridium perfringens was isolated from 10-8 % of the diarrhoeic goat kids but not from non-diarrhoeic goat kids or lambs. Salmonella arizonae was isolated from a diarrhoeic goat kid (2-7 %) and the clinical characteristics of the outbreaks where these two latter enteropathogens were found different from the rest. Picobirnaviruses were detected in a diarrhoeic lamb. No coronaviruses were detected using a bovine coronavirus ELISA. No evidence was found of synergistic effect between the agents studied. Enteric pathogens were not found in four (8-7 %) and three (20%) outbreaks of diarrhoea in lambs and goat kids, respectively.

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Virus Infections in Immunocompromised Patients

Simmons

2010

Topley &Amp; Wilson's Microbiology and Microbial Infections

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Viruses with bisegmented double-stranded rna in pig faeces

Cited by 48 publications

References 6 publications

Animal Picobirnavirus

Animal Picobirnavirus

Role of enteric pathogens in the aetiology of neonatal diarrhoea in lambs and goat kids in Spain

Virus Infections in Immunocompromised Patients

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