Virus concentration and purification by a microfluidic filtering system with an integrated PEGylated antifouling membrane

Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives

“…Capture efficiency was improved with two orders of magnitude and LOD was improved 10-fold using this system. Kim et al, (2019) proposed a microfluidic system to concentrate viral particles. In this system, the poly (ethylene glycol) methacrylate (PEGMA) membrane was integrated into the chip and the virus was concentrated through autonomous and continuous perfusion.…”

Intermediate layer-based bonding techniques for polydimethylsiloxane/digital light processing 3D-printed microfluidic devices

“…Finally, the burst test structure with a PDMS/tape composite intermediate layer was sandwiched between two flat plastic plates and baked at 65 °C for 3 h. A weight of 300 g was placed on the sample to achieve a uniform and strong bond between the PDMS top part and the partiallycured PDMS layer. [34,35]. For UV glue bonding, we used a stamp-and-stick process [36].…”