Virological Surveillance of Influenza-Like Illness Among Children in Ghana, 2008–2010

Bonney, Joseph Humphrey Kofi; Kronmann, Karl; Lindan, Christina; Asante, Ivy A.; Parbie, Prince Kofi; Aboagye, James; Amankwah, Joseph; Odoom, John Kofi; Adjabeng, Michael; Nzussouo, Ndahwouh Talla; Ahadzie, Lawson; Barthel, Robert Vince; Cornelius, Clair; Amofah, George; Oyofo, Buhari A.; Ampofo, William

doi:10.1093/infdis/jis577

Cited by 27 publications

(34 citation statements)

References 13 publications

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“…Similarly, we found that 15.1% of ILI and 6.6% of SARI patients enrolled in our study tested positive for influenza A or B viruses over the 2 years period . For ILI cases, the prevalence of influenza increased with age, similarly to other studies . Particularly in very young children, the broad definition of “influenza‐like illness” leads to the inclusion of patients with respiratory infections caused by other pathogens, especially respiratory syncytial virus and rhinoviruses .…”

Section: Discussionsupporting

confidence: 69%

“…Also successive waves of influenza circulation in 2014‐2015 were due to viruses from different subtypes and clades, as revealed by phylogenetic analyses of 14 A(H1N1)pdm09 and 29 A(H3N2) strains, suggesting new seeding events at least twice a year and sometimes within short time intervals (Figure ). Despite a possible lack of sensitivity due to non‐homogenous surveillance efforts, influenza viruses do not seem to circulate year‐round at background levels in Burkina Faso, similarly to Niger (analysis of FluNet data for Niger ‐ not shown ‐ and data from Mainassara et al) and unlike Côte d'Ivoire, Ghana or Togo, with a different climate. In the future, increased efforts toward sampling and individual strain characterization will help to better understand the temporal occurrence of influenza activity, virus spread between countries and potential persistence within West Africa …”

Section: Discussionmentioning

confidence: 99%

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Epidemiology and molecular characterization of influenza viruses in Burkina Faso, sub‐Saharan Africa

Sanou

Wandaogo

Poda

et al. 2018

Influenza Resp Viruses

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BackgroundThe importance of influenza viruses in respiratory infections in sub‐Saharan Africa has been historically overlooked, including in Burkina Faso.ObjectivesThis study therefore aimed at evaluating the prevalence and seasonal occurrence of influenza viruses in children under 5 years old, at risk of influenza‐related complications, presenting with influenza‐like illness (ILI) or severe acute respiratory infection (SARI). The study also aimed at identifying the periods with increased influenza transmission for vaccination recommendations in Burkina Faso.MethodsFrom January 2014 to December 2015, ILI and SARI (2015 only) patients were recruited in six healthcare centers in Burkina Faso. Influenza A and B molecular detection and subtyping were performed. Clade clustering of a subset of A(H1N1)pdm09 and A(H3N2) strains was deduced by performing phylogenetic analyses on hemagglutinin gene sequences. Weekly surveillance data from FluNet (2011‐2013; 2016) and this study (2014‐2015) were used to identify periods of increased influenza activity.ResultsInfluenza A and B viruses were detected in 15.1% (112 of 743) of ILI and 6.6% (12 of 181) of SARI patients. Overall, influenza A viruses were largely predominant (81 of 124, 65.3%), with 69.1% of A(H3N2) and 30.9% of A(H1N1)pdm09 strains. Four waves of increased transmission were identified in 2014‐2015, each dominated by different influenza subtypes and clades. Between 2011 and 2016, periods of increased influenza activity varied in their frequency, duration, and timing.ConclusionInfluenza A and B viruses were detected in a substantial number of ILI and SARI cases in Burkina Faso. Vaccination in September‐October would likely protect the highest number of patients.

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Epidemiology and molecular characterization of influenza viruses in Burkina Faso, sub‐Saharan Africa

Sanou

Wandaogo

Poda

et al. 2018

Influenza Resp Viruses

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“…The obvious peaks in 2006 and 2009 were associated with a large epidemic or an outbreak of influenza, similar to the large-scale epidemic peak observed with the Victoria-like virus of influenza B that caused a flu outbreak at 12 schools in Ningbo from March to April 2006 [20]. The autumn peak in 2009 was largely influenced by the novel influenza A pH1N1 (pH1N1) activity, indicating the emergence of novel influenza viruses with pandemic potential [21], similar to the increased influenza activity during the pandemic period in Beijing, China [22]. After the pandemic period in 2009, the influenza epidemic intensity decreased in the following year because the population had acquired some level of protective antibodies after the pH1N1 infection.…”

Section: Discussionmentioning

confidence: 82%

Epidemiological Features and Forecast Model Analysis for the Morbidity of Influenza in Ningbo, China, 2006–2014

Wang

Feng

Liu

et al. 2017

IJERPH

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This study aimed to identify circulating influenza virus strains and vulnerable population groups and investigate the distribution and seasonality of influenza viruses in Ningbo, China. Then, an autoregressive integrated moving average (ARIMA) model for prediction was established. Influenza surveillance data for 2006–2014 were obtained for cases of influenza-like illness (ILI) (n = 129,528) from the municipal Centers for Disease Control and virus surveillance systems of Ningbo, China. The ARIMA model was proposed to predict the expected morbidity cases from January 2015 to December 2015. Of the 13,294 specimens, influenza virus was detected in 1148 (8.64%) samples, including 951 (82.84%) influenza type A and 197 (17.16%) influenza type B viruses; the influenza virus isolation rate was strongly correlated with the rate of ILI during the overall study period (r = 0.20, p < 0.05). The ARIMA (1, 1, 1) (1, 1, 0)12 model could be used to predict the ILI incidence in Ningbo. The seasonal pattern of influenza activity in Ningbo tended to peak during the rainy season and winter. Given those results, the model we established could effectively predict the trend of influenza-related morbidity, providing a methodological basis for future influenza monitoring and control strategies in the study area.

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“…Cough was one of the commonest symptoms reported. The reported cough could be pathological or non-pathological (Bonney et al, 2012). Though it is likely that a proportion of the symptoms reported may not be pathological, the prevalence of runny nose suggests a high probability of an upper respiratory tract infection (URTI).…”

Section: Discussionmentioning

confidence: 99%

Childhood Respiratory Morbidity and Cooking Practices Among Households in a Predominantly Rural Area of Ghana

Asante¹,

Kinney²,

Zandoh³

et al. 2016

AJID

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Background: Household air pollution is a leading risk factor for respiratory morbidity and mortality in developing countries where biomass fuel is mainly used for cooking. Materials and Method: A household cross-sectional survey was conducted in a predominantly rural area of Ghana in 2007 to determine the prevalence of respiratory symptoms and their associated risk factors. Household cooking practices were also assessed as part of the survey. Results: Household heads of twelve thousand, three hundred and thirty-three households were interviewed. Fifty-seven percent (7006/12333) of these households had at least one child less than five years of age. The prevalence of symptoms of acute lower respiratory infections (ALRI) was 13.7% (n= 957, 95% CI 12.8 -15.5%). A majority (77.8%, 95% CI, 77.7 -78.5%) of households used wood as their primary fuel. Majority of respondents who used wood as their primary fuel obtained them by gathering wood from their neighborhood (95.6%, 9177/9595) and used a 3-stone local stove for cooking (94.9%, 9101/9595). In a randomly selected subset of respondents, females were the persons who mostly gathered firewood from the fields (90.8%, 296/326) and did the cooking (94.8%, 384/406) for the household. Conclusion: Symptoms of ALRI reported by caregivers is high in the Kintampo area of Ghana where biomass fuel use is also high. There is the need to initiate interventions that use improved cook stoves and to test the health benefits of such interventions.

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Virological Surveillance of Influenza-Like Illness Among Children in Ghana, 2008–2010

Abstract: During the 3 years of influenza surveillance in Ghana, children aged <11 years bore a high burden of influenza-associated ILI.

Cited by 27 publications

References 13 publications

Epidemiology and molecular characterization of influenza viruses in Burkina Faso, sub‐Saharan Africa

Epidemiology and molecular characterization of influenza viruses in Burkina Faso, sub‐Saharan Africa

Epidemiological Features and Forecast Model Analysis for the Morbidity of Influenza in Ningbo, China, 2006–2014

Childhood Respiratory Morbidity and Cooking Practices Among Households in a Predominantly Rural Area of Ghana

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