“…Coronaviruses have been shown in several seroepidemiologic studies to be not uncommon in both pédiatrie and adult populations (18,19,38,40,48,53,61,62,75) but, in spite of this, recovery of these agents has been quite rare, as only thirty-two isolations have been reported since 1965 when the first strain, B814, was recovered in human embryonic trachea! organ culture (HETOC) by Tyrrell and Bynoe (15, 38, 45, 68,80,81).…”