Viral Hepatitis in Infancy and Childhood

Mowat, Alex P.

doi:10.1016/s0300-5089(21)00713-6

Cited by 7 publications

(2 citation statements)

References 72 publications

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“…Hepatitis B is fairly frequent in the 3-5-year-old age group; in the 9-II-year age group, the frequency is similar to that found in adults in Italy (3,11). It is higher than frequencies for children in northwestern Europe and North America (12,21). As suggested by other authors (21), early virus B infection might depend on the high intrafamilial viral diffusion that occurs in Naples (22,23).…”

Section: Discussionmentioning

confidence: 74%

See 1 more Smart Citation

Acute Viral Hepatitis in Childhood

Caporaso,

Coltorti,

Del Vecchio‐Blanco

et al. 1983

J. pediatr. gastroenterol. nutr.

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A study of 164 consecutive patients (97 males, 67 females; aged 3–11 years) with acute hepatitis was done. Hepatitis A was the most frequent etiologic type. It occurred in 82.7% of the 3–5‐year age group, and in 72.2% and 57.2% of the 6–8− and 9–11‐year age groups, respectively. Non‐A, non‐B hepatitis was rather infrequent (4.3%). Hepatitis B occurred in 13.7% of the 3–5‐year age group and reached 39.6% in the 9–11‐year age group. While all hepatitis A and non‐A, non‐B cases recovered within a relatively short time, hepatitis B patients recovered more slowly; two cases recovered 1 year after the onset of symptoms. Chronicity was demonstrated in 23.8% of hepatitis B patients 2 years after the onset of the disease. HB***8Ag clearance was slower in children than in adults. At 4 months, only 59% of patients had serum converted, and a chronic carrier state occurred in 13 of 42 subjects followed for up to 2 years (three healthy carriers and 10 with chronic hepatitis of various types). Our data show that persistence of HB***8Ag positivity does not always lead to chronicity in children. Of the eight patients HB***8Ag‐positive 1 year after the onset of symptoms, two recovered.

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Section: Discussionmentioning

confidence: 74%

“…Reports of longitudinal studies on the etiologic characteristics and clinical course of acute viral hepatitis in children are scarce (11,12). Our study was performed in a geographic area characterized by a high incidence of viral hepatitis and by a fairly wide diffusion of hepatitis B virus in the general population (13).…”

Section: Discussionmentioning

confidence: 99%