Viral exanthem with “Spins and needles sensation” on extremities of a COVID-19 patient: A self-reported case from an Indonesian medical frontliner

Putra, Bayushi Eka; Adiarto, Suko; Dewayanti, Santi; Juzar, Dafsah Arifa

doi:10.1016/j.ijid.2020.05.020

Cited by 42 publications

(51 citation statements)

References 6 publications

(8 reference statements)

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“…In one patient, oral lesions appeared simultaneously with systemic symptoms and in other patients, latency time was between 2 and 10 days. One patient had positive history of recurrent aphthous stomatitis (RAS) and two patients had positive PCR for herpes simplex virus (HSV) 4‐8,37 . Aphthous‐like lesions without necrosis were observed in younger patients with mild infection, whilst aphthous‐like lesions with necrosis and hemorrhagic crusts were observed more frequently in older patients with immunosuppression and severe infection.…”

Section: Discussionmentioning

confidence: 99%

Oral manifestations ofCOVID‐19 disease: A review article

Iranmanesh

Khalili

Amiri

et al. 2020

Dermatologic Therapy

228

271

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Dysgeusia is the first recognized oral symptom of novel coronavirus disease (COVID‐19). In this review article, we described oral lesions of COVID‐19 patients. We searched PubMed library and Google Scholar for published literature since December 2019 until September 2020. Finally, we selected 35 articles including case reports, case series and letters to editor. Oral manifestations included ulcer, erosion, bulla, vesicle, pustule, fissured or depapillated tongue, macule, papule, plaque, pigmentation, halitosis, whitish areas, hemorrhagic crust, necrosis, petechiae, swelling, erythema, and spontaneous bleeding. The most common sites of involvement in descending order were tongue (38%), labial mucosa (26%), and palate (22%). Suggested diagnoses of the lesions were aphthous stomatitis, herpetiform lesions, candidiasis, vasculitis, Kawasaki‐like, EM‐like, mucositis, drug eruption, necrotizing periodontal disease, angina bullosa‐like, angular cheilitis, atypical Sweet syndrome, and Melkerson‐Rosenthal syndrome. Oral lesions were symptomatic in 68% of the cases. Oral lesions were nearly equal in both genders (49% female and 51% male). Patients with older age and higher severity of COVID‐19 disease had more widespread and sever oral lesions. Lack of oral hygiene, opportunistic infections, stress, immunosuppression, vasculitis, and hyper‐inflammatory response secondary to COVID‐19 are the most important predisposing factors for onset of oral lesions in COVID‐19 patients.

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Section: Discussionmentioning

confidence: 99%

Oral manifestations ofCOVID‐19 disease: A review article

Iranmanesh

Khalili

Amiri

et al. 2020

Dermatologic Therapy

228

271

View full text Add to dashboard Cite

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“…Of note, there was no fibrin deposition 25 . Finally, a case report from Indonesia described a patient who experienced a “pins and needles” sensation with lenticular papules that desquamated and seemed consistent with pernio‐like lesions 26 …”

Section: Resultsmentioning

confidence: 99%

Dermatologic manifestations of COVID‐19: a comprehensive systematic review

et al. 2020

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Recent reports have suggested that there may be dermatologic manifestations of COVID‐19. We searched 12 databases for peer‐reviewed or pre‐print published studies until July 15, 2020, for this PRISMA‐compliant review (CRD42020182050). We used the Oxford Center for Evidence‐Based Medicine Levels of Evidence to facilitate data synthesis. From 86 retrieved studies, we collated data on 2,560 patients with dermatologic manifestations of COVID‐19. The most common findings were chilblains/pernio‐like lesion (51.5%), erythematous maculopapular rashes (13.3%), and viral exanthem (7.7%). Average pediatric age was 12.9 years (SD 3.6) and adult was 34.2 years (SD 21.8). Average latency from time of upper respiratory illness symptoms to cutaneous findings was 1.5 days (SD 2.9) in children and 7.9 days (SD 10.7) in adults, ranging from −3 to 38 days. Roughly one‐tenth in both populations were otherwise asymptomatic or presented with only skin findings for the entirety of the disease course; 13.3% (pediatrics) and 5.3% (adults) presented with skin issues first. Dermatologic findings may play an important role in identifying cases early and serve as an important proxy to manage spread. Further prospective data collection with international prospective registries is needed.

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“…Interestingly, there is one self-reported case of a doctor with COVID-19 complaining of 'pin and needles' sensation in palms and soles with subsequent appearance of acral macules similar to our study patients. 10 In COVID-19 patients, palms and soles provide useful information and should be routinely checked. Redness, swelling of the hands and feet along with burning sensation (erythrodysesthesia), fine desquamation and acral macules may support the diagnosis of COVID-19.…”

Section: Palmoplantar Erythrodysesthesia: a Diagnostic Sign Of Covid-19mentioning

confidence: 99%