Viral Etiology of Acute Respiratory Infections in Hospitalized and Outpatient Children in Buenos Aires, Argentina

Marcone, Débora Natalia; Ellis, Anna; Videla, Cristina; Ekstrom, Jorge; Ricarte, Carmen; Carballal, Guadalupe; Vidaurreta, Santiago; Echavarría, Marcela

doi:10.1097/inf.0b013e31827cd06f

Cited by 64 publications

(73 citation statements)

References 30 publications

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“…Our findings highlight the fact that three quarters of infants or young children with any respiratory symptoms carry at least one virus. This rate of detection concords with previous studies in developed and African countries [15], [16], [17], [18]. Most of the viruses were identified by molecular diagnosis, and direct immunofluorescence yield was low but concordant with previous work [19], achieving only 10% of positive results.…”

Section: Discussionsupporting

confidence: 87%

Viral Etiology of Respiratory Tract Infections in Children at the Pediatric Hospital in Ouagadougou (Burkina Faso)

Ouédraogo¹,

Traoré²,

Bi³

et al. 2014

PLoS ONE

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BackgroundAcute respiratory infections (ARIs) are a major cause of morbidity and mortality in children in Africa. The circulation of viruses classically implicated in ARIs is poorly known in Burkina Faso. The aim of this study was to identify the respiratory viruses present in children admitted to or consulting at the pediatric hospital in Ouagadougou.MethodsFrom July 2010 to July 2011, we tested nasal aspirates of 209 children with upper or lower respiratory infection for main respiratory viruses (respiratory syncytial virus (RSV), metapneumovirus, adenovirus, parainfluenza viruses 1, 2 and 3, influenza A, B and C, rhinovirus/enterovirus), by immunofluorescence locally in Ouagadougou, and by PCR in France. Bacteria have also been investigated in 97 samples.Results153 children (73.2%) carried at least one virus and 175 viruses were detected. Rhinoviruses/enteroviruses were most frequently detected (rhinovirus n = 88; enterovirus n = 38) and were found to circulate throughout the year. An epidemic of RSV infections (n = 25) was identified in September/October, followed by an epidemic of influenza virus (n = 13), mostly H1N1pdm09. This epidemic occurred during the period of the year in which nighttime temperatures and humidity were at their lowest. Other viruses tested were detected only sporadically. Twenty-two viral co-infections were observed. Bacteria were detected in 29/97 samples with 22 viral/bacterial co-infections.ConclusionsThis study, the first of its type in Burkina Faso, warrants further investigation to confirm the seasonality of RSV infection and to improve local diagnosis of influenza. The long-term objective is to optimize therapeutic management of infected children.

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Section: Discussionsupporting

confidence: 87%

Viral Etiology of Respiratory Tract Infections in Children at the Pediatric Hospital in Ouagadougou (Burkina Faso)

Ouédraogo¹,

Traoré²,

Bi³

et al. 2014

PLoS ONE

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“…It is not yet clear if these multiple viruses identified are all infectious agents. In our study, multiple infections were found with a lower rate (n=4, 2.8%) compared to other studies (10%-43.5%) (14)(15)(16)(17)(18)(19). One of these was association of RV and EV which was diagnosed as URTI and the other three were associations of HBoV and RSV which were diagnosed as LRTI.…”

Section: Discussioncontrasting

confidence: 52%

Evaluation of epidemiological and clinical features of influenza and other respiratory viruses

Aktürk¹,

Sütçü²,

Badur³

et al. 2015

Turk Pediatri Ars

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Aim: In our study, we aimed to clinically and epidemiologically evaluate respiratory tract infections the viral agents of which were detected by molecular methods and to compare influenza and other respiratory tract viruses in this context. Material and Methods:The records of 178 patients aged above 2 years who presented to pediatric emergency outpatient clinic with fever and respiratory tract infection findings between December 2013 and April 2014 were examined retrospectively. Results: At least one respiratory tract pathogen was detected by polymerase chain reaction in 78.6% (n=140) of the patients: influenza A 33.5%, influenza B 16.4%, respiratory syncytial virus 9.2%, adenovirus 7.8%, rhinovirus 7.1%, coronavirus 7.1%, human metapneumovirus 5.7%, human bocavirus 5.7%, parainfluenza virus 3.5%, coinfection 2.8%. The mean age of the patients was 6.3±3.6 years. Sixty-nine patients (49.2%) were aged between 2 and 5 years. Seventy-one patients (50.7%) were aged 5 years and above. Upper respiratory tract infection was found with a rate of 65.7% and lower respiratory tract infection was found with a rate of 34.2%. It was observed that the distribution of respiratory tract viruses showed variance by age groups. Influenza A infection was observed with the highest rate in both age groups. Influenza B was the second leading agent (p=0.008) above the age of 5 years and respiratory syncytial virus was the second leading agent in the 2-5 year age group (p=0.003). Influenza viruses were detected in 55.9% of 118 patients who were found to be compatible with the definition of "influenza-like illness" specified in the Center for Disease Control and Prevention guidelines and other viral agenst were detected in 44%. No difference could be found between the clinical pictures and radiological findings caused by influenza and other respiratory tract viruses. Conclusions: In this study, it was concluded that influenza and other respiratory viruses can not be differentiated definitely by clinical and radiological findings, though there are some differences. (Turk Pediatri Ars 2015; 50: 217-25)

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“…Otros suelen presentar foco evidente, que ya no son sujeto de nuestro estudio: rinovirus, influenza A y B, parainfluenza y adenovirus. 26 Las IBG causadas por E. coli y Streptococcus agalactiae (SGB) son más frecuentes en neonatos. El uso de profilaxis intraparto para prevención de la sepsis por SGB se relacionó con una disminución de la prevalencia de este agente.…”

Section: ¿Cuáles Son Los Agentes Más Frecuentes Relacionados Con Fsf?unclassified

Consenso para el uso adecuado de antibióticos en el niño menor de 36 meses con fiebre sin foco de infección evidente. Texto completo

2017

Arch Argent Pediat

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Viral Etiology of Acute Respiratory Infections in Hospitalized and Outpatient Children in Buenos Aires, Argentina

Abstract: HRV were significant pathogens associated with bronchiolitis and pneumonia, especially in hospitalized patients. Both, HRV and coinfections, were risk factors for hospitalization. These findings support the importance of including HRV detection in children with acute respiratory infection.

Cited by 64 publications

References 30 publications

Viral Etiology of Respiratory Tract Infections in Children at the Pediatric Hospital in Ouagadougou (Burkina Faso)

Viral Etiology of Respiratory Tract Infections in Children at the Pediatric Hospital in Ouagadougou (Burkina Faso)

Evaluation of epidemiological and clinical features of influenza and other respiratory viruses

Consenso para el uso adecuado de antibióticos en el niño menor de 36 meses con fiebre sin foco de infección evidente. Texto completo

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