Viral Encephalomyelitis of Pigeons: Identification and Characterization of the Virus

Tantawi, H. H.; Falluji, M. M. Al; Sheikhly, F. Al

doi:10.2307/1589594

Cited by 24 publications

(7 citation statements)

References 2 publications

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“…[3] as an agent affecting pigeons that caused visceral lesion such as necrosis especially in liver. Herpesvirus infection was frequently identified in young pigeons and free-ranging birds from different countries of Europe [12,16,20-22], Iraq [23], USA [1,13,15], Australia [4,14] and Canada [5]. The virus is antigenically related to CoHV-1 and was found in falcons and owls [1,4,5,12-16].…”

Section: Discussionmentioning

confidence: 99%

Phylogenetic analysis of Columbid herpesvirus-1 in rock pigeons, birds of prey and non-raptorial birds in Poland

et al. 2013

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BackgroundThe identity of herpesviruses isolated in Europe from domestic pigeons (Columbid herpesvirus-1 - CoHV-1) as well as falcons and owls remains unknown. All these herpesviruses are antigenically and genetically related. The falcons and owls are thought to have become infected during the ingestion of pigeon meat thus suggesting the virus’s capacity to infect a wide range of hosts. The aim of the conducted study was to detect the occurrence of CoHV-1 and estimating the similarities and differences in the DNA-dependent DNA polymerase gene of herpesviruses isolated from domestic pigeons, birds of prey and non-raptorial free-ranging birds in Poland.ResultsThe study has shown the presence of CoHV-1 in 20.4% (18/88) in the examined birds. In case of one CoHV-1, infected Peregrine Falcon (Falco peregrinus), neurological signs were observed. Nucleotide sequencing of the DNA-dependent DNA polymerase gene, showed a high similarity among Polish strains (100%), independently from the species of the affected birds. Only one compared CoHV-1 strain - KP 21/23 originating from Germany showed a slightly lower similarity at a level of 99.1%. Further analysis has shown the identity of DNA-dependent DNA polymerase of CoHV-1 strains and other herpesviruses present in poultry as well as other birds ranged from 35.4 to 44.9%. Interestingly CoHV-1 infection was also confirmed for the first time in four non-raptorial birds.ConclusionsThe current study has shown a high similarity of CoHV-1 strains and the possible transmission of herpesviruses between domestic rock pigeons and free-ranging birds including raptors and non-raptorial birds. Further studies focused on cloning and the analysis of the whole CoHV-1 genome which is needed to explain the role of the observed similarities and differences between field strains of columbid herpesviruses.

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Section: Discussionmentioning

confidence: 99%

Phylogenetic analysis of Columbid herpesvirus-1 in rock pigeons, birds of prey and non-raptorial birds in Poland

et al. 2013

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“…Pigeon paramyxovirus type 1 (PPMV-1) is an antigenic and host variant of classical NDV of chickens, which is responsible for ND-like infectious disease of pigeons, and some strains could be distinguished from classical NDV by hemagglutination inhibition (HI) tests and monoclonal antibodies [ 11 , 12 , 13 ]. The earliest PPMV-1 isolate, designated Iraq’78, was derived from a herpesvirus stock that had been implicated in viral encephalomyelitis of pigeons in Iraqi [ 14 , 15 ]. Some PPMV-1 strains identified by restriction cleavage site analysis of the F gene were classified as a distinct subgroup within genotype VI (sub-genotype VIb), which were responsible for the third epizootic in the 1980s and might derive from Middle East viruses [ 13 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Genomic Characterizations of Six Pigeon Paramyxovirus Type 1 Viruses Isolated from Live Bird Markets in China during 2011 to 2013

Wang

Liu

et al. 2015

PLoS ONE

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The genomes of six pigeon paramyxovirus type 1 (PPMV-1) isolated from symptomless pigeons in live poultry markets during the national active surveillance from 2011 to 2013 were sequenced and analyzed in this study. The complete genome lengths of all isolates were 15,192 nucleotides with the gene order of 3’-NP-P-M-F-HN-L-5’. All isolates had the same motif of 112RRQKRF117 at the cleavage site of the fusion protein, which was typical of velogenic Newcastle disease virus (NDV). Several mutations were identified in the functional domains of F and HN proteins, including fusion peptide, heptad repeat region, transmembrane domains and neutralizing epitopes. Phylogenetic analysis based on sequences of complete genomes and six genes revealed that all isolates belonged to genotype VI in class II, but at least 2 sub-genotypes were identified. Most isolates were placed into sub-genotype VIb with the exception of pi/GX/1015/13, which was classified in sub-genotype VIa. The obvious antigenic difference between PPMV-1 isolates and La Sota strain was found based on the R-value calculated by cross hemagglutination inhibition (HI) assay. These results provided the evidence that PPMV-1 could be detected from healthy pigeons, and our study may be useful in designing vaccines used in pigeon, and developing molecular diagnostic tools to monitor and prevent future PPMV-1 outbreaks.

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“…Although cross reactions between PPDV and other avian H V have not yet been described, both cross reactive proteins (TANTAWI et al, 1979;NAKAJIMA et al, 1990) and genetic homologies between different species of H V (Krsfrl et al, 1988; GRIFFIN, 1989) have already been reported. For this reason, even though the developed ELISA assay exhibited n o cross-reactivity with proteins of the tested avian HV, further studies will be necessary in order to determine the exact specificity of the assay developed in this study.…”

Section: Discussionmentioning

confidence: 99%

“…To date, a large variety of avian herpesviruses (HV) have been isolated from many avian species (BURTSCHER, 1965;TANTAWI et a]., 1979;DHARMA and SUDANA, 1982; MUELLER, 1990). Since about 8,000 species of birds have been described up to now (WOLTERS, 1982), it is expected that more different types of H V will be isolated in the future.…”

Section: Introductionmentioning

confidence: 99%

Development of an Experimental ELISA for the Detection of Antigens and Antibodies to the Virus of Pacheco Disease using Monoclonal Antibodies

Abdala

1994

Journal of Veterinary Medicine, Series B

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Monoclonal antibodies (Mabs) against one of the strains of Pacheco Parrot's Disease (PPD) were produced and characterized. An enzyme-linked immunosorbent assay (ELISA) for the rapid detection of antigen and antibody to PPD was developed. The antigen ELISA could detect up to 11 7 ng/ml of purified virus material. To overcome the requirement for large amounts of purified viral antigen, the microtitre trays were initially coated with Mabs prepared against purified PPD virus (PPDV). A relatively crude viral preparation could then be used to coat the trays. Using one more step of incubation between the viral preparation and a test sera, the same ELISA protocol could be used for screening antibody against PPDV. The blocking ELISA with a detection range of 625ng

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Viral Encephalomyelitis of Pigeons: Identification and Characterization of the Virus

Cited by 24 publications

References 2 publications

Phylogenetic analysis of Columbid herpesvirus-1 in rock pigeons, birds of prey and non-raptorial birds in Poland

Phylogenetic analysis of Columbid herpesvirus-1 in rock pigeons, birds of prey and non-raptorial birds in Poland

Genomic Characterizations of Six Pigeon Paramyxovirus Type 1 Viruses Isolated from Live Bird Markets in China during 2011 to 2013

Development of an Experimental ELISA for the Detection of Antigens and Antibodies to the Virus of Pacheco Disease using Monoclonal Antibodies

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