Videomicroscopy of port-wine stains: Correlation of location and depth of lesion

Description and Analysis of Treatments for Port-wine Stain Birthmarks

“…Additional optical instruments under development for PWS skin diagnostics and therapy evaluation include videomicroscopy, 37 modulated imaging, 38 cross-polarized diffuse reflectance imaging, 23 and laser speckle imaging. 39 Laser speckle imaging is of particular interest because it can serve as a relatively low-cost, wide-field, vascular imaging instrument to evaluate skin perfusion dynamics intraoperatively.…”

Progress toward Understanding Vascular Malformations

“…Hypoxia upregulated by VEGF iss caused at least in part by an increased transcription mediated by hypoxia-induced factor-1 (HIF-1) (62).. The deprivation of oxygen and nutrients such as glucose may regulate gene expression in an overlappingg pattern (63).…”

A Comparison of Acquired Port-wine Stain with Congenital Port-wine Stain Using an Image Analyzer

“…The authors concluded that the therapeutic result was dependent on both the vessel diameter and its depth. Eubanks and McBurney 16 used videomicroscopy and found that PWS in areas that typically respond well to laser treatment (V3 dermatome, neck, and trunk) were more likely to have a superficial pattern and PWS in areas that have a poorer response to therapy (V2 dermatome, distal extremities) were more likely to have a deeper pattern. Hence, it was suggested that both the depth and the diameter of the ectatic blood vessels in PWS have influence on the response to PDL.…”

“…To demonstrate correlation between clinical features and therapeutic response, many investigations were done with no unanimity [10][11][12][13][14] . Histopathologic examinations of PWS have also been done to establish the relationship between pathologic parameters and therapeutic responses [7][8][9][15][16][17] . Hohenleutner et al 15 of a diameter up to 150μm were completely coagulated.…”