“…[1] As a class of nitrogen-containing five-membered heterocycles, pyrazoles are characterized by the presence of an important structural motif that explains their wide-ranging use in pharmaceutical, [2] chemical, [3] and agrochemical industries. [4] There have been many pyrazole derivatives produced for various medicinal purposes including antidepressants, anticonvulsants, [5] antituberculars, [6] antitumors, [7] antagonists of GABA receptors, insecticides, [8] anticancers, [9] antipyretics, [10] anti-inflammatory agents, and antimicrobials. [11] Some of the most potent derivatives of pyrazoles are depicted below (Figure 1).…”