A Novel Electrochemical Sensor for Detection of Baicalein in Human Serum Based on DUT‐9/Mesoporous Carbon Composite

Wang, Haixu; Yuan, Shuang; Zhou, Ming; Guo, Liping

doi:10.1002/elan.201900496

Cited by 10 publications

(6 citation statements)

References 64 publications

(70 reference statements)

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“…In addition, experts in the field have recently presented electrochemical approaches, because of their higher sensitivity and selectivity, acceptable accuracy, shorter analysis time, simplicity, affordable equipment, and portability. − …”

Section: Introductionmentioning

confidence: 99%

Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Tajik

Afshar

Shamsaddini

et al. 2022

Ind. Eng. Chem. Res.

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Cancer treatment by chemotherapy exploits one or more anticancer drugs to kill cancer cells. Because of the various side effects of chemotherapy drugs, sensitive determination of these drugs is one of the greatest challenges of adjuvant therapy. This study introduced the preparation of a selective and sensitive electrochemical sensor based on a carbon paste electrode (CPE) modified with Fe 3 O 4 @MoS 2 /reduced graphene oxide nanocomposite and ionic liquid (IL) (Fe 3 O 4 @MoS 2 /rGO/ILCPE) to determine dasatinib in the presence of doxorubicin. Results showed very good electrocatalytic activities of Fe 3 O 4 @MoS 2 /rGO/ILCPE toward the oxidation of dasatinib in phosphate buffer solution (PBS) (pH 7.0). The differential pulse voltammetry (DPV), chronoamperometry, and cyclic voltammetry (CV) were employed for studying the electrochemical behaviors of dasatinib on the modified electrode. Based on the optimal condition, we observed a linear increase of the voltammetric current by enhancing the dasatinib concentration in ranges between 0.02 μM and 390.0 μM. The detection limit for the dasatinib was equal to 6.0 nM, based on 3S b / m. Moreover, the modified CPE was used for the detection of dasatinib in the presence of doxorubicin. The corresponding electrochemical signals emerged as two well-resolved oxidation peaks with the considerable peak potential differences of 0.38 V. Finally, dasatinib and doxorubicin detection in the real samples were estimated by examining the functionality of our new sensor that showed acceptable recovery.

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Section: Introductionmentioning

confidence: 99%

Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Tajik

Afshar

Shamsaddini

et al. 2022

Ind. Eng. Chem. Res.

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“…These results indicate that the nanozyme electrochemical sensor has been successfully fabricated. Compared with cyclic voltammetry, differential pulsed voltammetry (DPV) has higher sensitivity and wide detection range [37,38]. Therefore, electrochemical detection of BNP was performed under optimized conditions by DPV.…”

Section: Electrochemical Detection Of Bnpmentioning

confidence: 99%

Dual‐signal immuno‐competitive determination of brain natriuretic peptide based on magnetic nanozyme

Xia

Song

et al. 2023

Electroanalysis

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Brain natriuretic peptide (BNP) has been a disease marker in the diagnosis of heart failure. In this study, gold nanoparticles modified with Hemin (H‐AuNPs) as nanozymes were used to oxidize ABST and MB to amplified colorimetric and electrochemical redox signals respectively. BNP was combined with H‐AuNPs (BNP‐H‐AuNPs) through electrostatic adsorption to construct competitive nanozyme probes. Target BNP in the sample compete with BNP‐H‐AuNPs to bind the antibody‐modified magnetic nanoparticles (AntiBNP‐MNPs). Due to the excellent catalytic performance of the nanozyme, BNP can be observed well by colorimetric and electrochemical assays. Electrochemical method ensured more accurate detection of BNP with a wide detection range (1–200 pg/mL) and a low detection of limit (0.03 pg/mL). Meanwhile, the results of the experiment can be easily observed with the naked eye by simple colorimetric method with a range from 5 ng/mL to 25 ng/mL and a limit of detection down to 80.3 pg/mL. Thus, based on the important role of H‐AuNPs, this assay has exhibited potential value of detection the other small proteins through this competitive nanozyme method.

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“…Thus, the development of an accurate and sensitive method of detection for baicalein has aroused widespread attention. In this context, electrochemical sensors have attracted broad-scale research because of their high sensitivity, rapid response, simplified operation and low cost [ 8 , 9 , 10 ]. For an electrochemical sensing platform, selecting suitable electrode materials to promote detection performance it is a critical factor.…”

Section: Introductionmentioning

confidence: 99%

TiO2-MXene/PEDOT:PSS Composite as a Novel Electrochemical Sensing Platform for Sensitive Detection of Baicalein

Xue

Shi

Wang³

et al. 2023

Molecules

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In this work, TiO2-MXene/poly (3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS) composite was utilized as an electrode material for the sensitive electrochemical detection of baicalein. The in-situ growth of TiO2 nanoparticles on the surface of MXene nanosheets can effectively prevent their aggregation, thus presenting a significantly large specific surface area and abundant active sites. However, the partial oxidation of MXene after calcination could reduce its conductivity. To address this issue, herein, PEDOT:PSS films were introduced to disperse the TiO2-MXene materials. The uniform and dense films of PEDOT:PSS not only improved the conductivity and dispersion of TiO2-MXene but also enhanced its stability and electrocatalytic activity. With the advantages of a composite material, TiO2-MXene/PEDOT:PSS as an electrode material demonstrated excellent electrochemical sensing ability for baicalein determination, with a wide linear response ranging from 0.007 to 10.0 μM and a lower limit of detection of 2.33 nM. Furthermore, the prepared sensor displayed good repeatability, reproducibility, stability and selectivity, and presented satisfactory results for the determination of baicalein in human urine sample analysis.

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A Novel Electrochemical Sensor for Detection of Baicalein in Human Serum Based on DUT‐9/Mesoporous Carbon Composite

Cited by 10 publications

References 64 publications

Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Dual‐signal immuno‐competitive determination of brain natriuretic peptide based on magnetic nanozyme

TiO2-MXene/PEDOT:PSS Composite as a Novel Electrochemical Sensing Platform for Sensitive Detection of Baicalein

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A Novel Electrochemical Sensor for Detection of Baicalein in Human Serum Based on DUT‐9/Mesoporous Carbon Composite

Cited by 10 publications

References 64 publications

Fe3O4@MoS2/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Fe3O4@MoS2/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Dual‐signal immuno‐competitive determination of brain natriuretic peptide based on magnetic nanozyme

TiO2-MXene/PEDOT:PSS Composite as a Novel Electrochemical Sensing Platform for Sensitive Detection of Baicalein

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Product

Resources

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Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin

Fe₃O₄@MoS₂/rGO Nanocomposite/Ionic Liquid Modified Carbon Paste Electrode for Electrochemical Sensing of Dasatinib in the Presence of Doxorubicin