VI-RADS score and tumor contact length in MRI: A potential method for the detection of muscle invasion in bladder cancer

Akçay, Ahmet; Yağcı, Ahmet Baki; Çelen, Sinan; Özlülerden, Yusuf; Türk, Nilay Şen; Ufuk, Furkan

doi:10.1016/j.clinimag.2021.02.026

Cited by 23 publications

(13 citation statements)

References 19 publications

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“…Our study showed excellent agreement among the readers in the assessment of VI-RADS score in MIBC estimation for all the sequences (T2-WI, DWI, and DCE) and both protocols (bp-and mp-MRI). Similarly, excellent agreement among the readers was reported in other studies in the literature [11,21,23,24]. In contrast, Barchetti et [17,27,28].…”

Section: Discussionsupporting

confidence: 79%

“…Delli Pizzi et al, in their study of 38 BC patients, showed that the AUC of the VI-RADS score for detecting MIBC ranged from 0.90 to 0.95 for the bp-MRI protocol and from 0.87 to 0.90 for the mp-MRI protocol [12]. In other studies in the literature, the AUC value in the detection of MIBC was reported as 0.953-0.968, 0.940, 0.966, 0.87-0.94, and 0.95 [11,[21][22][23][24]. The results we obtained with both the bp-and mp-MRI protocols were similar to the studies in the literature.…”

Section: Discussionmentioning

confidence: 86%

“…MRI has been reported to have high diagnostic performance in differentiating NMIBC from MIBC and in estimating extravesical extension [9]. In particular, multiparametric MRI (mp-MRI), which combines morphological T2-weighted image (T2-WI), and functional sequences such as diffusion-WI (DWI) and dynamic contrast-enhanced (DCE) images, has been shown to improve tumor detection and local staging, and to be used in monitoring treatment response [4,10,11]. In 2018, Vesical Imaging Reporting and Data System (VI-RADS) was published to standardize mp-MRI reporting, facilitate communication between different disciplines, and potentially improve patient management (Table 1) [5].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of the diagnostic accuracy and validity of biparametric MRI and multiparametric MRI-based VI-RADS scoring in bladder cancer; is contrast material really necessary in detecting muscle invasion?

et al. 2021

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Purpose (1) To evaluate the accuracy and validity of the biparametric MRI (bp-MRI), including T2-weigthed image (WI) and DWI sequences, and the availability of an alternative to the multiparametric MRI (mp-MRI), for the muscle-invasiveness assessment of bladder cancer (BC). ( 2) To evaluate the diagnostic performance and agreement of readers with different experiences in the abdominal imaging of using both protocols. Methods Preoperative bladder mp-MRI was performed on 128 patients with a initial diagnosis of BC. Two sets of images, set 1 (bp-MRI) and set 2 (mp-MRI), were independently evaluated by both readers. Descriptive statistics, including sensitivity, specificity, accuracy, and area under the curve (AUC), for VI-RADS scores were calculated using ≥ 4 as the cutoff for muscle invasion for each reader and image sets. Inter-reader agreement was evaluated using the Cohen's kappa coefficient. ResultsThe sensitivity ranged between 90.3-93.5% and 87.1-90.3%, specificity ranged between 96.6-99.1% and 91.6-96.6%, accuracy ranged between 96-97.3% and 91.3-94.6%, and AUC ranged between 0.947-0.951 and 0.919-0.921, for bp-MRI and mp-MRI, and reader 1 and reader 2, respectively. No significant differences were shown in diagnostic performance for either reader between both the protocols (p = 0.238 and 0.318). There was excellent agreement among the readers in the VI-RADS scores, using both protocols. Conclusion A bp-MRI protocol has a diagnostic accuracy comparable to an mp-MRI protocol for the detection of muscleinvasive BC using the VI-RADS criteria. Also, in both MRI protocols, the reader's experience does not appear to significantly affect diagnostic performance when using the VI-RADS criteria.

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Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

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Comparison of the diagnostic accuracy and validity of biparametric MRI and multiparametric MRI-based VI-RADS scoring in bladder cancer; is contrast material really necessary in detecting muscle invasion?

et al. 2021

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“…Patient, tumor, and study characteristics are summarized in Table 1. Of the 20 included articles, n = 11 were conducted in Asia (n = 5 in China [15][16][17], n = 4 in Japan [18][19][20][21], n = 2 in Korea [22,23]), n = 6 in Europe (n = 4 in Italy [6,[24][25][26], n = 1 in Spain [27]) n = 1 in Turkey [28] and 3 in other continents (2 in Egypt [29,30], 1 in Brazil [31]). Range of eligible study time was comprised in between 2019 and 2021 and included patients who had been treated for BCa between 2005 and 2020.…”

Section: Location Design and Characteristics Of The Studies Populationmentioning

confidence: 99%

The accuracy of Vesical Imaging-Reporting and Data System (VI-RADS): an updated comprehensive multi-institutional, multi-readers systematic review and meta-analysis from diagnostic evidence into future clinical recommendations

et al. 2022

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Purpose To determine through a comprehensive systematic review and meta-analysis the cumulative diagnostic performance of vesical imaging-reporting and data system (VIRADS) to predict preoperative muscle-invasiveness among different institutions, readers, and optimal scoring accuracy thresholds. Methods PubMed, Cochrane and Embase were searched from inception up to May 2021. Sensitivity (Sn), Specificity (Sp) were first estimated and subsequently pooled using hierarchical summary receiver operating characteristics (HSROC) modeling for both cut-off ≥ 3 and ≥ 4 to predict muscle-invasive bladder cancer (MIBC). Further sensitivity analysis, subgroup analysis and meta-regression were conducted to investigate contribution of moderators to heterogeneity. Results In total, n = 20 studies from 2019 to 2021 with n = 2477 patients by n = 53 genitourinary radiologists met the inclusion criteria. Pooled weighted Sn and Sp were 0.87 (95% CI 0.82–0.91) and 0.86 (95% CI 0.80–0.90) for cut-off ≥ 3 while 0.78 (95% CI 0.74–0.81) and 0.94 (95% CI 0.91–0.96) for cut-off ≥ 4. The area under the HSROC curve was 0.93 (95% CI 0.90–0.95) and 0.91 (95% CI 0.88–0.93) for cut-off ≥ 3 and ≥ 4, respectively. Meta-regression analyses showed no influence of clinical characteristics nor cumulative reader’s experience while study design and radiological characteristics were found to influence the estimated outcome. Conclusion We demonstrated excellent worldwide diagnostic performance of VI-RADS to determine pre-trans urethral resection of bladder tumor (TURBT) staging. Our findings corroborate wide reliability of VI-RADS accuracy also between different centers with varying experience underling the importance that standardization and reproducibility of VI-RADS may confer to multiparametric magnetic resonance imaging (mpMRI) for preoperative BCa discrimination.

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“…Standard reporting and data systems (RADS) have been established for several solid tumors, including prostate cancer [37,38], hepatocellular carcinoma [39], head and neck squamous cell carcinoma [40], solitary bone tumors [41], bladder cancer [42], breast cancer [43], lymph node involvement by cancer [44], and lung cancer [45]. These RADS have enabled rules for imaging techniques, terminology for reports, definitions of tumor features, and treatment response, with less practice variation and reproducible tumor classification.…”

Section: Introductionmentioning

confidence: 99%

Glioblastoma Surgery Imaging—Reporting and Data System: Standardized Reporting of Tumor Volume, Location, and Resectability Based on Automated Segmentations

Kommers

Bouget

Pedersen

et al. 2021

Cancers

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Treatment decisions for patients with presumed glioblastoma are based on tumor characteristics available from a preoperative MR scan. Tumor characteristics, including volume, location, and resectability, are often estimated or manually delineated. This process is time consuming and subjective. Hence, comparison across cohorts, trials, or registries are subject to assessment bias. In this study, we propose a standardized Glioblastoma Surgery Imaging Reporting and Data System (GSI-RADS) based on an automated method of tumor segmentation that provides standard reports on tumor features that are potentially relevant for glioblastoma surgery. As clinical validation, we determine the agreement in extracted tumor features between the automated method and the current standard of manual segmentations from routine clinical MR scans before treatment. In an observational consecutive cohort of 1596 adult patients with a first time surgery of a glioblastoma from 13 institutions, we segmented gadolinium-enhanced tumor parts both by a human rater and by an automated algorithm. Tumor features were extracted from segmentations of both methods and compared to assess differences, concordance, and equivalence. The laterality, contralateral infiltration, and the laterality indices were in excellent agreement. The native and normalized tumor volumes had excellent agreement, consistency, and equivalence. Multifocality, but not the number of foci, had good agreement and equivalence. The location profiles of cortical and subcortical structures were in excellent agreement. The expected residual tumor volumes and resectability indices had excellent agreement, consistency, and equivalence. Tumor probability maps were in good agreement. In conclusion, automated segmentations are in excellent agreement with manual segmentations and practically equivalent regarding tumor features that are potentially relevant for neurosurgical purposes. Standard GSI-RADS reports can be generated by open access software.

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VI-RADS score and tumor contact length in MRI: A potential method for the detection of muscle invasion in bladder cancer

Cited by 23 publications

References 19 publications

Comparison of the diagnostic accuracy and validity of biparametric MRI and multiparametric MRI-based VI-RADS scoring in bladder cancer; is contrast material really necessary in detecting muscle invasion?

Comparison of the diagnostic accuracy and validity of biparametric MRI and multiparametric MRI-based VI-RADS scoring in bladder cancer; is contrast material really necessary in detecting muscle invasion?

The accuracy of Vesical Imaging-Reporting and Data System (VI-RADS): an updated comprehensive multi-institutional, multi-readers systematic review and meta-analysis from diagnostic evidence into future clinical recommendations

Glioblastoma Surgery Imaging—Reporting and Data System: Standardized Reporting of Tumor Volume, Location, and Resectability Based on Automated Segmentations

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