Vestibulocervical reflexes in idiopathic Parkinson disease

Paired neurophysiological and clinical study of the brainstem at different stages of Parkinson’s Disease

“…The high prevalence of abnormal VEMPs in PD patients, in comparison with matched controls, is in line with data reported by previous works dealing with this issue, which were, nevertheless, focused on cVEMPs only (Pollak et al, 2009;Potter-Nerger et al, 2012). VEMP abnormalities could be explained by the well-known age-related effects on VEMP morphology (Welgampola and Colebatch, 2001a,b;Rosengren et al, 2011), for which a progressive reduction with age of both the number of peripheral receptors and excitability of nuclear vestibular neurons (Lopez et al, 1997;Tang et al, 2001) are causal factors.…”

“…In PD, the cVEMP has only been tested in patients with the full-blown disease, where a general pattern of absence and of amplitude reduction has been reported (Pollak et al, 2009;Potter-Nerger et al, 2012).…”

Correlation of impaired subjective visual vertical and postural instability in Parkinson's disease

“…On the other hand, PD patients had abnormal or absent vestibular evoked myogenic potentials (VEMP), which measures the vestibulocolic reflex (from saccule, thru vestibular nuclei and medial vestibulospinal tract to the sternocleidomastoid muscle). No correlation was found between abnormal VEMP and disease stage or falls [31]. The VEMP pathway is different and shorter than the graviceptive pathway and evaluates the function of the saccule (afferent) and the vestibulospinal tract (efferent).…”

Mood and behavioural effects of subthalamic stimulation in Parkinson's disease

“…results, [44][45][46][47][48][49][50][51][52][53] some data have suggested a link between vestibular dysfunction and lateral trunk deviations.…”