Objective To assess the efficacy of transcutaneous electrical nerve stimulation (TENS) in the treatment of vestibulodynia.Design Double-arm randomised placebo-controlled trial.Setting An outpatient department for vulval disease.Population Forty women with vestibulodynia, a vestibular discomfort mostly reported as a burning pain, occurring in the absence of relevant visible findings or a specific, clinically identifiable, neurological disorder.Methods Twice a week active TENS or sham treatment were delivered through a vaginal probe via a calibrated dual channel YSY-EST device. Women of both groups underwent 20 treatment sessions.Main outcome measures Visual analogue scale (VAS), the short form of the McGill-Melzack Pain Questionnaire (SF-MPQ), the Marinoff Scale for dyspareunia and the Female Sexual Function Index questionnaire (FSFI) were assessed at baseline, at the end of treatment and at follow up 3 months after the end of treatment.Results The VAS and SF-MPQ scores (6.2 ± 1.9 and 19.5 ± 11.9 before treatment, respectively) improved significantly in the active TENS group (2.1 ± 2.7, P = 0.004 and 8.5 ± 10.7, P = 0.001, respectively), but not in the placebo group. The Marinoff dyspareunia scale and the FSFI also showed a significant improvement.Conclusions TENS is a simple, effective and safe shortterm (3 months) treatment for the management of vestibulodynia.