‘Vestibular compensation’: Neural plasticity and its relations to functional recovery after labyrinthine lesions in frogs and other vertebrates

Dieringer, N.

doi:10.1016/0301-0082(95)80009-w

Cited by 114 publications

(72 citation statements)

References 114 publications

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“…During further spaceflight, normal activity might be restored due to adaptive, neuroplastic properties of the vestibular system (cf. Precht and Dieringer, 1985;Smith and Curthoys, 1989;Dieringer, 1995). In cases of spinal plasticity induced by hemilabyrinthectomy, otolith mediated input is considered to be the event that initiates the activation of adaptive (compensatory) mechanisms (Dieringer, 1995).…”

Section: Adaptation During Exposure To Altered Gravitational Forcesmentioning

confidence: 99%

“…Precht and Dieringer, 1985;Smith and Curthoys, 1989;Dieringer, 1995). In cases of spinal plasticity induced by hemilabyrinthectomy, otolith mediated input is considered to be the event that initiates the activation of adaptive (compensatory) mechanisms (Dieringer, 1995). In-flight, otolithic input is available, and it originates from translatory movements during swimming (cf.…”

Section: Adaptation During Exposure To Altered Gravitational Forcesmentioning

confidence: 99%

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Altered gravitational forces affect the development of the static vestibuloocular reflex in fish (Oreochromis mossambicus)

2000

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Section: Adaptation During Exposure To Altered Gravitational Forcesmentioning

confidence: 99%

Section: Adaptation During Exposure To Altered Gravitational Forcesmentioning

confidence: 99%

Altered gravitational forces affect the development of the static vestibuloocular reflex in fish (Oreochromis mossambicus)

2000

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“…This process is attributed to neuronal plasticity that takes place mainly in the brainstem and cerebellum (Curthoys and Halmagyi 1995;Dieringer 1995;Vibert et al 1999;Darlington and Smith 2000;Dutia 2010;Peusner et al 2012;Beraneck and Idoux 2012).…”

mentioning

confidence: 99%

Sequential [18F]FDG µPET whole-brain imaging of central vestibular compensation: a model of deafferentation-induced brain plasticity

et al. 2014

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Unilateral inner ear damage is followed by a rapid behavioural recovery due to central vestibular compensation. In this study, we utilized serial [(18)F]Fluoro-deoxyglucose ([(18)F]FDG)-µPET imaging in the rat to visualize changes in brain glucose metabolism during behavioural recovery after surgical and chemical unilateral labyrinthectomy, to determine the extent and time-course of the involvement of different brain regions in vestibular compensation and test previously described hypotheses of underlying mechanisms. Systematic patterns of relative changes of glucose metabolism (rCGM) were observed during vestibular compensation. A significant asymmetry of rCGM appeared in the vestibular nuclei, vestibulocerebellum, thalamus, multisensory vestibular cortex, hippocampus and amygdala in the acute phase of vestibular imbalance (4 h). This was followed by early vestibular compensation over 1-2 days where rCGM re-balanced between the vestibular nuclei, thalami and temporoparietal cortices and bilateral rCGM increase appeared in the hippocampus and amygdala. Subsequently over 2-7 days, rCGM increased in the ipsilesional spinal trigeminal nucleus and later (7-9 days) rCGM increased in the vestibulocerebellum bilaterally and the hypothalamus and persisted in the hippocampus. These systematic dynamic rCGM patterns during vestibular compensation, were confirmed in a second rat model of chemical unilateral labyrinthectomy by serial [(18)F]FDG-µPET. These findings show that deafferentation-induced plasticity after unilateral labyrinthectomy involves early mechanisms of re-balancing predominantly in the brainstem vestibular nuclei but also in thalamo-cortical and limbic areas, and indicate the contribution of spinocerebellar sensory inputs and vestibulocerebellar adaptation at the later stages of behavioural recovery.

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“…Unter physiologischen Bedingungen herrscht dort in Ruhe ein Tonusgleichgewicht, das bei spezifischen Reizungen, v. a. also Kopfbewegungen, zu effektorischen Antworten führt, die eine erfolgreiche Orientierung im Raum garantieren. Dazu [3]. Für diese klinischen Beobachtungen gibt es neuronale Entsprechungen auf dem Niveau der Vestibulariskerne.…”

Section: Pathophysiologische Grundlagenunclassified

Fahrtüchtigkeit bei vestibulären Läsionen

Hamann

2002

HNO

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1086Bedingt durch die immer noch zunehmende Motorisierung der Bevölkerung stellt sich in der Praxis des niedergelassenen HNO-Arztes vermehrt die Frage nach der Fahrtüchtigkeit eines Patienten, der einen Ausfall eines Vestibularapparates oder eine andere vestibuläre Störung erlitten hat. Besonders problematisch ist es, wenn der Patient selbst subjektiv beschwerdefrei ist, eine Läsion aber noch nachweisbar ist, oder der Patient noch über Beschwerden klagt, obwohl eine vestibuläre Störung nicht mehr objektivierbar ist. Im Folgenden wird der Versuch unternommen, einer Lösung dieser Probleme unter Berück-sichtigung bekannter Mechanismen der Erholungsvorgänge im vestibulären System und durch Darstellung der notwendigen Untersuchungsmethoden sowie exakter Definitionen der einzelnen Krankheitsbilder und ihrer Verläufe nahezukommen.

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‘Vestibular compensation’: Neural plasticity and its relations to functional recovery after labyrinthine lesions in frogs and other vertebrates

Cited by 114 publications

References 114 publications

Altered gravitational forces affect the development of the static vestibuloocular reflex in fish (Oreochromis mossambicus)

Altered gravitational forces affect the development of the static vestibuloocular reflex in fish (Oreochromis mossambicus)

Sequential [18F]FDG µPET whole-brain imaging of central vestibular compensation: a model of deafferentation-induced brain plasticity

Fahrtüchtigkeit bei vestibulären Läsionen

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