Altered gravitational forces affect the development of the static vestibuloocular reflex in fish (Oreochromis mossambicus)

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity

“…The decrease in otolith calcification was already previously described [103, 104] and was proposed to involve a regulatory mechanism linking gravity sensing to the production of carbonic anhydrase and other matrix proteins in the inner ear [105–107]. Thus, the decrease in otolith calcification after prolonged exposure to 3g was expected, but it also emphasizes the specificity of the observed increase in ossification.…”

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity

“…The decrease in otolith calcification was already previously described [103, 104] and was proposed to involve a regulatory mechanism linking gravity sensing to the production of carbonic anhydrase and other matrix proteins in the inner ear [105–107]. Thus, the decrease in otolith calcification after prolonged exposure to 3g was expected, but it also emphasizes the specificity of the observed increase in ossification.…”

Microgravity-induced modifications of the vestibuloocular reflex inXenopus laevistadpoles are related to development and the occurrence of tail lordosis

“…Significant differences were also obtained for the rVOR gain. The augmentation of the rVOR in microgravity tadpoles with respect to the 1g-ground controls resembled the observation in fish (Oreochromis mossambicus) after a 9-day space flight and points to a sensitization of the neuronal network underlying the rVOR (Sebastian et al, 2001).…”

“…The most likely mechanism for reflex augmentation in the older tadpoles (cf. Fig.·7) is sensitization of the vestibular system by gravity deprivation, as also shown in bullfrogs (Bracchi et al, 1975), fish (Boyle et al, 2000;Sebastian et al, 2001;Wiederhold et al, 2003) and men (Clément et al, 2001). Recordings from the vestibular nerve of bullfrogs during microgravity revealed an initial depression of spontaneous activity but a recovery and overcompensation during ongoing microgravity exposure (Bracchi et al, 1975).…”

The Sensitivity of an Immature Vestibular System to Altered Gravity

“…The critical period for the rVOR of X. laevis is restricted to the period of the first appearance of the reflex (Horn and Gabriel, 2011). An age-related sensitivity of the rVOR to orbital weightlessness was also described for fish (Oreochromis mossambicus) (Sebastian et al, 2001).…”

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity

“…The decrease in otolith calcification was already previously described [103, 104] and was proposed to involve a regulatory mechanism linking gravity sensing to the production of carbonic anhydrase and other matrix proteins in the inner ear [105–107]. Thus, the decrease in otolith calcification after prolonged exposure to 3g was expected, but it also emphasizes the specificity of the observed increase in ossification.…”

Microgravity-induced modifications of the vestibuloocular reflex inXenopus laevistadpoles are related to development and the occurrence of tail lordosis

“…Significant differences were also obtained for the rVOR gain. The augmentation of the rVOR in microgravity tadpoles with respect to the 1g-ground controls resembled the observation in fish (Oreochromis mossambicus) after a 9-day space flight and points to a sensitization of the neuronal network underlying the rVOR (Sebastian et al, 2001).…”

“…The most likely mechanism for reflex augmentation in the older tadpoles (cf. Fig.·7) is sensitization of the vestibular system by gravity deprivation, as also shown in bullfrogs (Bracchi et al, 1975), fish (Boyle et al, 2000;Sebastian et al, 2001;Wiederhold et al, 2003) and men (Clément et al, 2001). Recordings from the vestibular nerve of bullfrogs during microgravity revealed an initial depression of spontaneous activity but a recovery and overcompensation during ongoing microgravity exposure (Bracchi et al, 1975).…”

The Sensitivity of an Immature Vestibular System to Altered Gravity

“…The critical period for the rVOR of X. laevis is restricted to the period of the first appearance of the reflex (Horn and Gabriel, 2011). An age-related sensitivity of the rVOR to orbital weightlessness was also described for fish (Oreochromis mossambicus) (Sebastian et al, 2001).…”

Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity

“…The decrease in otolith calcification was already previously described [103, 104] and was proposed to involve a regulatory mechanism linking gravity sensing to the production of carbonic anhydrase and other matrix proteins in the inner ear [105–107]. Thus, the decrease in otolith calcification after prolonged exposure to 3g was expected, but it also emphasizes the specificity of the observed increase in ossification.…”

Microgravity-induced modifications of the vestibuloocular reflex inXenopus laevistadpoles are related to development and the occurrence of tail lordosis

“…Significant differences were also obtained for the rVOR gain. The augmentation of the rVOR in microgravity tadpoles with respect to the 1g-ground controls resembled the observation in fish (Oreochromis mossambicus) after a 9-day space flight and points to a sensitization of the neuronal network underlying the rVOR (Sebastian et al, 2001).…”

“…The most likely mechanism for reflex augmentation in the older tadpoles (cf. Fig.·7) is sensitization of the vestibular system by gravity deprivation, as also shown in bullfrogs (Bracchi et al, 1975), fish (Boyle et al, 2000;Sebastian et al, 2001;Wiederhold et al, 2003) and men (Clément et al, 2001). Recordings from the vestibular nerve of bullfrogs during microgravity revealed an initial depression of spontaneous activity but a recovery and overcompensation during ongoing microgravity exposure (Bracchi et al, 1975).…”

The Sensitivity of an Immature Vestibular System to Altered Gravity

“…The critical period for the rVOR of X. laevis is restricted to the period of the first appearance of the reflex (Horn and Gabriel, 2011). An age-related sensitivity of the rVOR to orbital weightlessness was also described for fish (Oreochromis mossambicus) (Sebastian et al, 2001).…”