“…Considering that many substances of interest exhibit limited solubility in water, several attempts have been proposed to encapsulate such compounds, deliver them effectively, and release in a controlled manner at the site of action. Colloidal particles such as dendrimers, micelles, capsules, liposomes and polymersomes exhibit adequate size, high loading capacity, and sufficient stability which make them frequently used in the mentioned applications [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. However, several aspects need to be considered during the design and development of such carriers.…”