Vertigo as One of the Symptoms of Lyme Disease

Sowula, Klaudia; Szaleniec, Joanna; Dworak, Mateusz; Przeklasa, Maria; Maraj, Małgorzata; Ceranowicz, Piotr; Tomik, Jerzy

doi:10.3390/jcm10132814

Cited by 4 publications

(5 citation statements)

References 22 publications

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“…Although it is present very often in elderly, it cannot be ignored as a symptom, as it can also indicate that the LD has spread to the nervous system. In studies by Sowula et al, vertigo was presented by 76% of the examined LD patients [37]. In the current study, the students responded that the systems or organs most often affected by disease are the nervous system, skin, and the osteoarticular and cardiovascular systems.…”

Section: Discussionmentioning

confidence: 49%

Lyme borreliosis – state of the knowledge among medical students

Borowski¹,

Kupisz²,

Długosz³

et al. 2023

J Pre Clin Clin Res.

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Introduction and Objective. Lyme disease (LD) is becoming a serious problem worldwide. It is a bacterial infection caused by Gram-negative spirochaetes Borrelia burgdorferi sensu lato which are spread by tick bite, and are recognized as one of the most important tick-borne diseases. People spending time in the forests, meadows, and parks, or working in such environments are endangered to tick bites, which may cause the infection. Even though not each one of the parasites carries the disease, the illness itself is a serious condition and can simulate many other diseases, which is why it is often called 'the great imitator'. Therefore, it is very important to know the early symptoms of LD, as it can be cured effectively by antibiotics. The aim of this study was to determine whether young adults have sufficient knowledge regarding LD, how often tick bites occur within this population, and how many of them have been diagnosed with the illness in the past. Materials and method. Data was collected with the use of a survey completed by 201 first-year medical students. Results. The majority of the students had basic knowledge regarding the etiology, symptoms, and vectors of LD. There is a necessity to improve knowledge in the field of treatment, prophylaxis, and tick removal techniques. Half of the study participants had been bitten by a tick and some of them were diagnosed with LD. Conclusions. Most of the participants reported a tick bite in the past, and/or confirmed an infection. The awareness level regarding the sickness needs to be improved in some aspects, with the use of social campaigns or advertisements. This would help with better recognition of the disease in the future.

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Section: Discussionmentioning

confidence: 49%

Lyme borreliosis – state of the knowledge among medical students

Borowski¹,

Kupisz²,

Długosz³

et al. 2023

J Pre Clin Clin Res.

View full text Add to dashboard Cite

show abstract

“…While most commonly associated with flu-like symptoms and a characteristic erythema migrans rash, Lyme disease can also cause various neurologic symptoms, including vertigo [42 ▪▪ ]. The prevalence of Lyme disease-associated vertigo varies widely among studies [17 ▪ ,43,44]. Sowula et al [17 ▪ ] proposed that the pathogenesis of vertigo in Lyme disease may be related to the neurotoxic effects of Borrelia burgdorferi on the vestibular system.…”

Section: Mimics Of Meniere's Diseasementioning

confidence: 99%

“…The prevalence of Lyme disease-associated vertigo varies widely among studies [17 ▪ ,43,44]. Sowula et al [17 ▪ ] proposed that the pathogenesis of vertigo in Lyme disease may be related to the neurotoxic effects of Borrelia burgdorferi on the vestibular system.…”

Section: Mimics Of Meniere's Diseasementioning

confidence: 99%

“…One theory postulates there may be a viral etiology of Meniere's disease, with evidence implicating acute or persistent viral infections such as herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein Barr virus (EBV), influenza virus, adenovirus (AV), Coxsackie virus B, measles and Varicella Zoster virus (VZV) [12–16]. Furthermore, infectious diseases such as neurosyphilis and Lyme disease can mimic Meniere's disease, presenting with similar symptoms and complicating the diagnosis and management of the condition [17 ▪ ,18,19]. Additionally, autoimmune disorders such as systemic lupus erythematosus and rheumatoid arthritis may also serve as Meniere's disease mimics [20].…”

Section: Introductionmentioning

confidence: 99%

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Infectious causes and mimickers of meniere's disease

Kurtzman

Sioshansi

2023

Current Opinion in Otolaryngology &Amp; Head &Amp; Neck Surgery

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Purpose of review To review the evidence of a possible viral etiology of Meniere's disease, the role of antiviral therapy, as well as other infectious disease processes that may mimic Meniere's disease. Better understanding of the etiology of Meniere's disease and the role of various infectious disease processes may allow for more effective diagnosis and management. Recent findings There is evidence that viral infections – to Herpes simplex virus, cytomegalovirus, Epstein Barr virus, influenza, adenovirus, Coxsackie virus B, and Varicella Zoster Virus – may be involved in the development of Meniere's disease, however the evidence is inconsistent and the underlying mechanism remains theoretical. Nevertheless, antiviral therapy may be effective for a subset of patients with Meniere's disease. Lastly, other infectious diseases including Lyme disease and syphilis can present with symptoms similar to Meniere's disease. It is important to discern these from Meniere's disease to determine the appropriate treatment. Summary There is a paucity of high-quality evidence to support a viral etiology of Meniere's disease, and the current evidence appears circumstantial and inconsistent. Additional research is necessary to establish the mechanism and causative pathogens. Antiviral therapy may provide therapeutic benefit for a subset of patients with Meniere's disease. Furthermore, clinicians should be aware of other infectious mimics of Meniere's disease and include them in the differential diagnosis of patients presenting with Meniere's-like symptoms. Research on this subject continues to evolve, and data from these studies represent a growing repository of evidence that can be used to guide clinical decision-making.

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“…Abducens nerve palsy has been documented in isolation as well as with trochlear involvement, with optic nerve perineuritis, and with oculomotor palsy [ 81 , 82 , 83 , 84 ]. Vestibulocochlear nerve involvement is rare and can lead to hearing loss and vertigo [ 85 ], with longer infection leading to greater likelihood of permanent hearing deficits [ 86 ]. Involvement of the recurrent laryngeal nerve, a branch of the vagus nerve, is extremely rare; deficits are typically unilateral and cause hoarseness or sore throat, though in rare instances bilateral involvement can necessitate supplemental oxygen [ 87 ] or mechanical ventilation [ 88 ].…”

Section: Cranial Neuropathy and Lyme Diseasementioning

confidence: 99%

Neuropsychiatric Lyme Disease and Vagus Nerve Stimulation

Biniaz-Harris,

Kuvaldina,

Fallon

2023

Antibiotics

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Lyme disease, the most common tick-borne disease in the United States, is caused by infection with the spirochete Borrelia burgdorferi. While most patients with acute Lyme disease recover completely if treated with antibiotics shortly after the onset of infection, approximately 10–30% experience post-treatment symptoms and 5–10% have residual symptoms with functional impairment (post-treatment Lyme disease syndrome or PTLDS). These patients typically experience pain, cognitive problems, and/or fatigue. This narrative review provides a broad overview of Lyme disease, focusing on neuropsychiatric manifestations and persistent symptoms. While the etiology of persistent symptoms remains incompletely understood, potential explanations include persistent infection, altered neural activation, and immune dysregulation. Widely recognized is that new treatment options are needed for people who have symptoms that persist despite prior antibiotic therapy. After a brief discussion of treatment approaches, the article focuses on vagus nerve stimulation (VNS), a neuromodulation approach that is FDA-approved for depression, epilepsy, and headache syndromes and has been reported to be helpful for other diseases characterized by inflammation and neural dysregulation. Transcutaneous VNS stimulates the external branch of the vagus nerve, is minimally invasive, and is well-tolerated in other conditions with few side effects. If well-controlled double-blinded studies demonstrate that transcutaneous auricular VNS helps patients with chronic syndromes such as persistent symptoms after Lyme disease, taVNS will be a welcome addition to the treatment options for these patients.

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Vertigo as One of the Symptoms of Lyme Disease

Cited by 4 publications

References 22 publications

Lyme borreliosis – state of the knowledge among medical students

Lyme borreliosis – state of the knowledge among medical students

Infectious causes and mimickers of meniere's disease

Neuropsychiatric Lyme Disease and Vagus Nerve Stimulation

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