Vertical Periodontal Ligament Distraction – a New Method for Aligning Ankylosed and Displaced Canines

Wilmes, Benedict; Drescher, Dieter

doi:10.1007/s00056-009-8811-y

Cited by 14 publications

(14 citation statements)

References 22 publications

(47 reference statements)

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“…New kinds of mechanics and treatment options became possible due to the new anchorage quality. [1][2][3] The anterior palate especially has been used more and more as an insertion site for mini-implants. This region is characterized by plenty of bone of high quality 4 covered with a thin mucosa, which allows a sufficient insertion depth.…”

Section: Introductionmentioning

confidence: 99%

Mini-implant stability at the initial healing period: A clinical pilot study

Nienkemper

Wilmes

Pauls

et al. 2013

The Angle Orthodontist

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Section: Introductionmentioning

confidence: 99%

Mini-implant stability at the initial healing period: A clinical pilot study

Nienkemper

Wilmes

Pauls

et al. 2013

The Angle Orthodontist

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“…[3][4][5][6][7] Because of their versatility they have made new kinds of mechanics and treatment options possible. 8,9 However, one disadvantage of these anchorage devices is a failure rate that is still too high. Two systematic reviews in the literature report mean overall failure rates of 16.4%.…”

Section: Introductionmentioning

confidence: 99%

Measurement of mini-implant stability using resonance frequency analysis

Nienkemper

Wilmes

Panayotidis

et al. 2012

The Angle Orthodontist

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Objective: To investigate whether resonance frequency analysis (RFA) is suitable to measure orthodontic mini-implant stability. Implant size significantly affects the level of resonance frequency. Regarding the operating mode of RFA, it has to be proven whether the resonance frequency of mini-implants in bone fits the range of frequency emitted by the Osstell ISQ device. Material and Methods: For this purpose the SmartPegs in the Osstell ISQ device were modified to fit with the inner screw thread of orthodontic mini-implants, and 110 mini-implants were inserted into porcine pelvic bone. RFA was performed parallel and perpendicular to the run of superficial bone fibers. A suitability test, Periotest, was also performed in the same directions. Compacta thickness was measured using cone-beam computed tomography. Correlation tests and linear regression analysis were carried out between the three methods. Results: The RFA showed a mean Implant Stability Quotient value of 36.36 6 2.67, and the Periotest mean value was 22.10 6 1.17. The differences between the two directions of measurement were statistically significant (P . .001) for RFA and the Periotest. There was a high correlation between RFA and the Periotest (r 5 20.90) and between RFA and compacta thickness (r 5 0.71). The comparison between the Periotest and compacta thickness showed a correlation coefficient of r 5 20.64. Conclusion:The present results suggest that RFA is feasible as a measurement method for orthodontic mini-implant stability. As a consequence, it could be used for clinical evaluation of current stability and allow stability-related loading of mini-implants to reduce the failure rate. (Angle Orthod. 2013;83:230-238.)

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“…Clinically, PDL distraction may successfully restore the adjacent alveolar bone [8–10]. Stretching-like stress has been found to increase expression of osteogenic genes and proteins such as alkaline phosphatase (ALP), bone morphogenetic protein (BMP)-2, BMP6, osterix (Osx), runt-related transcription factor-2 (Runx2), and MSX1 of human PDL cells [11–13].…”

Section: Introductionmentioning

confidence: 99%

Up-regulated osteogenic transcription factors during early response of human periodontal ligament stem cells to cyclic tensile strain

Tang¹,

Zhao²,

Zhang³

et al. 2012

aoms

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IntroductionAs one group of periodontal ligament (PDL) cells, human periodontal ligament stem cells (hPDLSCs) have been isolated and identified as mesenchymal adult stem cells (MSCs) since 2004. It has been well accepted that PDL sensitively mediates the transmission of stress stimuli to the alveolar bone for periodontal tissue remolding. Besides, the direction of MSCs differentiation has been verified regulated by mechanical signals. Therefore, we hypothesized that tensile strain might act on hPDLSCs differentiation, and the early response to mechanical stress should be investigated.Material and methodsThe hPDLSCs were cultured in vitro and isolated via a magnetic activated CD146 cell sorting system. After investigation of surface markers and other experiments for identification, hPDLSCs were subjected to cyclic tensile strain at 3,000 µstrain for 3 h, 6 h, 12 h, and 24 h, without addition of osteogenic supplements. In the control groups, the cells were cultured in similar conditions without mechanical stimulation. Then osteogenic related genes and proteins were analyzed by RT-PCR and western blot.ResultsCyclic tensile strain at 3,000 µstrain of 6 h, 12 h, and 24 h durations significantly increased mRNA and protein expressions of Satb2, Runx2, and Osx, which were not affected in unloaded hPDLSCs.ConclusionsWe indicate that hPDLSCs might be sensitive to cyclic tensile strain. The significant increase of Runx2, Osx and Satb2 expressions may suggest an early response toward osteogenic orientation of hPDLSCs.

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Vertical Periodontal Ligament Distraction – a New Method for Aligning Ankylosed and Displaced Canines

Cited by 14 publications

References 22 publications

Mini-implant stability at the initial healing period: A clinical pilot study

Mini-implant stability at the initial healing period: A clinical pilot study

Measurement of mini-implant stability using resonance frequency analysis

Up-regulated osteogenic transcription factors during early response of human periodontal ligament stem cells to cyclic tensile strain

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