Vertical and horizontal ridge augmentation using customized CAD/CAM titanium mesh with versus without resorbable membranes. A randomized clinical trial

Cucchi, Alessandro; Vignudelli, Elisabetta; Franceschi, Debora; Randellini, Emanuele; Lizio, Giuseppe; Fiorino, Antonino; Corinaldesi, Giuseppe

doi:10.1111/clr.13841

Cited by 44 publications

(91 citation statements)

References 67 publications

(74 reference statements)

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“…No covering of the augmented sites with a collagen membrane or platelet‐rich plasma (PRP) or platelet‐rich‐fibrin (PRF) was adopted in this trial since their usefulness was not demonstrated yet. (Cucchi et al, 2021; Torres et al, 2010). Two cases consisted of completely edentulous maxillary atrophies, with a period of 2 weeks of postoperative healing before wearing a relined denture for esthetic purposes only.…”

Section: Discussionmentioning

confidence: 99%

Guided bone regeneration using titanium mesh to augment 3‐dimensional alveolar defects prior to implant placement. A pilot study

Lizio

Pellegrino

Corinaldesi

et al. 2022

Clinical Oral Implants Res

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Section: Discussionmentioning

confidence: 99%

Guided bone regeneration using titanium mesh to augment 3‐dimensional alveolar defects prior to implant placement. A pilot study

Lizio

Pellegrino

Corinaldesi

et al. 2022

Clinical Oral Implants Res

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“…Finally, in Figure 5 , the H: titanium-reinforced d-PTFE (80.9%) has the best effect and F: TM + CM (20.6%) has the worst effect. Since the e-PTFE membrane has good biocompatibility and can protect against blood clots, it is regarded as the gold standard barrier functional material in clinical practice [ 13 , 14 ]. Additionally, the blue dots corresponding to the B group (e-PTFE) and C group (CCM) appear to overlap.…”

Section: Resultsmentioning

confidence: 99%

“…Two studies described membrane exposure, and both showed that the membrane exposure rate of the TM + CCM group was lower than that of the TM group [ 14 , 32 ].…”

Section: Complication Analysismentioning

confidence: 99%

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Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis

Zhang

Zhou

Yun

et al. 2022

BioMed Research International

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This study is aimed at performing a systematic review and a network meta-analysis of the effects of several membranes on vertical bone regeneration and clinical complications in guided bone regeneration (GBR) or guided tissue regeneration (GTR). We compared the effects of the following membranes: high-density polytetrafluoroethylene (d-PTFE), expanded polytetrafluoroethylene (e-PTFE), crosslinked collagen membrane (CCM), noncrosslinked collagen membrane (CM), titanium mesh (TM), titanium mesh plus noncrosslinked (TM + CM), titanium mesh plus crosslinked (TM + CCM), titanium-reinforced d-PTFE, titanium-reinforced e-PTFE, polylactic acid (PLA), polyethylene glycol (PEG), and polylactic acid 910 (PLA910). Using the PICOS principles to help determine inclusion criteria, articles are collected using PubMed, Web of Science, and other databases. Assess the risk of deviation and the quality of evidence using the Cochrane Evaluation Manual, and GRADE. 27 articles were finally included. 19 articles were included in a network meta-analysis with vertical bone increment as an outcome measure. The network meta-analysis includes network diagrams, paired-comparison forest diagrams, funnel diagrams, surface under the cumulative ranking curve (SUCRA) diagrams, and sensitivity analysis diagrams. SUCRA indicated that titanium-reinforced d-PTFE exhibited the highest vertical bone increment effect. Meanwhile, we analyzed the complications of 19 studies and found that soft tissue injury and membrane exposure were the most common complications.

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“…In the first 6 months after tooth extraction, horizontal bone loss of 3.96 mm and horizontal bone loss of 1.24 mm can be observed on average [ 2 ]. In order to regain sufficient bone volume, the following augmentation techniques can be used: bone blocks (autologous or allogeneic) [ 3 , 4 ] interposition bone grafting techniques such as vertical splitting [ 5 ], horizontal sandwich technique or a Le-Fort-I osteotomy [ 6 ], guided bone regeneration with titanium meshes [ 7 ], or sinus floor elevations [ 8 ]. Other less invasive treatment options include the use of zygomatic implants [ 9 ], tilted implants, or short implants [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Specially designed and CAD/CAM manufactured allogeneic bone blocks using for augmentation of a highly atrophic maxilla show a stable base for an all-on-six treatment concept: a case report

Pfaffeneder-Mantai

Meller

Schneider

et al. 2022

Maxillofac Plast Reconstr Surg

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Background In terms of a highly atrophic maxilla, bone augmentation still remains very challenging. With the introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) for allogeneic bone blocks, a new method for the treatment of bone deficiencies was created. This case report demonstrates the successful use of two specially designed and CAD/CAM manufactured allogeneic bone blocks for a full arch reconstruction of a highly atrophic maxilla with an all-on-six concept. Case presentation We report the case of a 55-year-old male patient with a highly atrophic maxilla and severe bone volume deficiencies in horizontal and vertical lines. In order to treat the defects, the surgeon decided to use a combination of two allogeneic bone blocks and two sinus floor augmentations. The bone blocks were fabricated from the data of a cone beam computed tomography (CBCT) using CAD/CAM technology. After the insertion of the two bone blocks and a healing period of 7 months, six dental implants were placed in terms of an all-on-six concept. The loading of the implants took place after an additional healing time of 7 months with a screw-retained prosthetic construction and with a milled titanium framework with acrylic veneers. Conclusion The presented procedure shows the importance of the precise design of CAD/CAM manufactured allogeneic bone blocks for the successful treatment of a highly atrophic maxilla. Proper soft-tissue management is one of the key factors to apply this method successfully.

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Vertical and horizontal ridge augmentation using customized CAD/CAM titanium mesh with versus without resorbable membranes. A randomized clinical trial

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri bution-NonCo mmercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

Cited by 44 publications

References 67 publications

Guided bone regeneration using titanium mesh to augment 3‐dimensional alveolar defects prior to implant placement. A pilot study

Guided bone regeneration using titanium mesh to augment 3‐dimensional alveolar defects prior to implant placement. A pilot study

Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis

Specially designed and CAD/CAM manufactured allogeneic bone blocks using for augmentation of a highly atrophic maxilla show a stable base for an all-on-six treatment concept: a case report

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