Versuche zur entdeckung neuer fungistatika-I

Zsolnai, T

doi:10.1016/0006-2952(60)90002-2

Cited by 35 publications

(3 citation statements)

References 23 publications

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“…Many bromophenols, including 2,6-DBP and 2,4,6-TBP, are known to possess fungicidal, bacteriocidal, ascaricidal, and molluscicidal activities (Zsolnai, 1960;Jeney and Zsolnai, 1967;Hashimoto, 1978). Consequently, it has been suggested that these compounds are produced by marine worms as defensive chemicals against microorganisms and some predatory marine animals (Sheikh and Djerassi, 1975;Higa et al, 1980;Woodin et al, 1987).…”

Section: Resultsmentioning

confidence: 99%

Distribution of Bromophenols in Species of Marine Polychaetes and Bryozoans from Eastern Australia and the Role of Such Animals in the Flavor of Edible Ocean Fish and Prawns (Shrimp)

Whitfield

Drew

Helidoniotis

et al. 1999

J. Agric. Food Chem.

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Sixteen species (44 samples) of marine polychaetes and 10 species (14 samples) of bryozoans from eastern Australia were analyzed by GC/MS for the key seafood flavor components 2- and 4-bromophenol, 2, 4- and 2,6-dibromophenol, and 2,4,6-tribromophenol. All five bromophenols were found in 91% of polychaetes and 64% of bryozoans. The remaining samples all contained at least three bromophenols. 2,4, 6-Tribromophenol was found in all polychaetes and bryozoans and, with few exceptions, was present in the highest concentrations. The total bromophenol content determined on a wet-weight basis varied widely between species: for polychaetes, from 58 ng/g for Australonuphis teres to 8.3 million ng/g for Barantolla lepte, and for bryozoans, from 36 ng/g for Cladostephus spongiosus to 1668 ng/g for Amathia wilsoni. Species of polychaetes with the highest concentrations of bromophenols were all collected from muddy environments. The possible effects that dietary polychaetes and bryozoans have on the ocean-, brine-, or iodine-like flavors of certain seafoods are discussed.

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Section: Resultsmentioning

confidence: 99%

Distribution of Bromophenols in Species of Marine Polychaetes and Bryozoans from Eastern Australia and the Role of Such Animals in the Flavor of Edible Ocean Fish and Prawns (Shrimp)

Whitfield

Drew

Helidoniotis

et al. 1999

J. Agric. Food Chem.

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“…This is in agreement with previous a report, in which phenols are described as generally, species-unspecific acting antimicrobials. 207 Benzoic acid (251), methyl p-hydroxybenzoate or methylparabene (258), and sorbic acid (19) are in use as preservatives. Both acids were adsorbed from yeast cells in the undissociated state and accumulated in the 'solid phase' of the cell.…”

Section: E Vapor Phase Activity Testsmentioning

confidence: 99%

Anticandidal low molecular compounds from higher plants with special reference to compounds from essential oils

Pauli

2005

Medicinal Research Reviews

104

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The most active low molecular weight compounds from higher plants against Candida species are compiled from a database of antimicrobials (Amicbase) to find out new hints on their mechanism of action. The selected compounds possess strong inhibitory activities in vitro against Candida species either in the agar diffusion test, bioautography, agar dilution test, serial dilution test, or activity in the vapour phase. The test conditions are listed thoroughly and aspects of the different methods and recent developments in the testing of anticandidal drugs are discussed. The anticandidal spectra of drugs, antiseptics, and disinfectants licensed on the major markets are given for comparison of activities with compounds from natural sources. So far known mechanisms of action are described and some new structure-activity relationships are deduced from relationships between biological activities and chemical and physical parameters. Main specific targets of natural anticandidals are the ergosterol pathway, respiratory chain, and chitin biosynthesis.

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“…In previous studies, the effect of halometabolites on microorganisms (Zsolnai 1960, Higa & Scheuer 1975b, Sheikh & Djerassi 1975, King 1988, Reineke 2003, fish (Malins et al 1987, Casillas & Myers 1989 and fish eggs (Reineke 2003) was generally toxic. The potent deterrent effect of halometabolites on epibenthic predation by fishes and crabs at environmentally realistic sediment concentrations in the nano-to micromolar range indicated that these compounds may potentially play an ecological role in sediments populated by infaunal organisms (King 1986, 1988, Cowart et al 2000, Reineke 2003.…”

Section: Introductionmentioning

confidence: 99%

Effects of halogenated metabolites from infaunal polychaetes on larval settlement of the spionid polychaete Streblospio benedicti

Esser¹,

Winterberg²,

Sebesvári³

et al. 2008

Mar. Ecol. Prog. Ser.

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Considering that a variety of infaunal polychaetes release halogenated metabolites with potent bactericidal effects into the surrounding sediment, we tested the hypothesis that polychaetederived halometabolites may either pose a direct negative effect on larvae or alter the bacterial community in surface sediments, and thus indirectly influence larval settlement. Commercially available halogenated compounds identical or similar to the dominant halometabolites found in Streblospio benedicti and Capitella sp. I served as experimental proxies in single-and multiple-choice settlement assays with larvae of S. benedicti. In multiple-choice assays, the hypothesis of a direct influence of halogenated proxies on larval settlement was verified with 1-chlorononane at concentrations of 3.5 µg g -1 sediment. A similar effect was not observed with 2, 6-dibromophenol. The no-choice assays did not show a direct influence of halometabolites on polychaete larvae. On the other hand, the hypothesis of an indirect influence of halogenated proxies on larval settlement via modification of the sediment microbial assemblage was clearly rejected. However, an analysis of similarity of the PCR-amplified bacterial genes coding for 16S rRNA corresponding to distinct phylotypes revealed a significant change in bacterial community richness between untreated and natural sediment spiked and incubated with halogenated proxies for 7 d. The change was characterized by the absence of up to 13 phylotypes and the appearance of up to 11 previously undetected phylotypes. The shift in bacterial community richness of sediments exposed to the halogenated proxies was not recognized by larvae, indicating that the halogenated proxies elicited no differential response in larvae of S. benedicti.

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Versuche zur entdeckung neuer fungistatika-I

Cited by 35 publications

References 23 publications

Distribution of Bromophenols in Species of Marine Polychaetes and Bryozoans from Eastern Australia and the Role of Such Animals in the Flavor of Edible Ocean Fish and Prawns (Shrimp)

Distribution of Bromophenols in Species of Marine Polychaetes and Bryozoans from Eastern Australia and the Role of Such Animals in the Flavor of Edible Ocean Fish and Prawns (Shrimp)

Anticandidal low molecular compounds from higher plants with special reference to compounds from essential oils

Effects of halogenated metabolites from infaunal polychaetes on larval settlement of the spionid polychaete Streblospio benedicti

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