Versatile fabrication of paper-based microfluidic devices with high chemical resistance using scholar glue and magnetic masks

From kirigami to three-dimensional paper-based micro-analytical device: cut-and-paste fabrication and mobile app quantitation

“…Very recently, Cardoso et al have explored the use of readily available scholar glue to create hydrophobic ow barriers, and the glue-coated paper was then exposed to UV/Vis light for cross-linking to maximize chemical resistance and stability. 7 Conceptually different from their innovation, herein we applied a minimal amount of adhesive spray, which is chemically stable and insoluble in water, 32 to assemble different layers of mPADs. A detailed comparison between the kPADs with other existing 3D mPADs in terms of equipment requirements, patterning method, and assembly approach has been presented as Table S1 in the ESI.…”

“…1,2 As one of the best supplements came into attention a decade ago, 3 micro-uidic paper-based analytical devices (mPADs) have attracted extensive attention as reviewed recently in literature. [4][5][6][7][8] Even compared with microuidic devices fabricated on traditional substrates (glass, quartz, silicon, metal, and polymer), [9][10][11][12][13] mPADs are advantageous in terms of cost-effectiveness, excellent biocompatibility, and ease of fabrication/operation. As the newest addition to the family, three-dimensional (3D) mPADs have shown their enhanced analytical performance in pumpfree distribution of uids in both vertical and lateral directions and improved throughput with high-density assays.…”

Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection

“…In addition, the acrylic lacquer lacks flexibility, causing the hydrophobic barriers to be fragile. Cardoso et al developed a spraying method using scholar glue to fabricating paper-based devices [36]. This method required only a spray system and a UV lamp.…”

Fabrication of paper microfluidic devices using a toner laser printer

“…1,[29][30][31][32][33] These mPADs were used to perform analytical assays for point-of-care diagnostics and environmental monitoring. 2,18,19,28,[34][35][36] Such methods of fabrication required particular materials (synthetic hydrophobic precursor [37][38][39] and photoresist 1,32 ) and equipment (wax printer, 20,21,[40][41][42][43][44][45] inkjet printer, 22,23 laser, 39,45 mask aligner, 1 and UV lamp 32,33,37,38 ) to create the devices. Fabrication of mPAD has been initially demonstrated via photolithography, while direct printing of hydrophobic materials has been developed as alternative routes.…”