Verrucous carcinoma of the back

Demonstration of Human Papillomavirus Type 2 in a Verrucous Carcinoma of the Foot

“…Since then, this neoplasm has been reported in nearly all parts of the body and particularly in the foot where it has been described as 'epithelioma cuniculatum' because of a notional resemblance to rabbit burrows . Clinically, this remarkable neoplasm is characterized by a progressive growth with destruction of local tissues but practically never metastascs [8][9][10]. HPV have been formally incrimi nated as etiologic agents in verrucous carcinoma.…”

Penile Verrucous Carcinoma

“…The etiology of penile verrucous carcinoma is un¬ clear, but infection, chronic phimosis, irritation, trauma, and poor hygiene have all been implicated as important factors in its development.1622 Also, uncir-Accepted for publication March15, 1990. Most authors now believe that entities such as giant condyloma of Buschke and Löwenstein; epithelioma cuniculatum; oral florid papillomatosis; and pseudoepitheliomatous, micaceous, and keratotic balanitis are all clinical variants of verrucous carcinoma.8,162326 As shown in Table 2, Mohs and Sahl23 have proposed a simplified classification for verrucous carcinoma that describes the major sites of involve¬ ment: panoral, genitogluteal, and plantar.…”

Verrucous ‘cuniculatum’ carcinoma of the sacral region

“…Regarding treatment, some authors have proposed radiation therapy for small lesions and radical surgery for extensive ones 2 . In our patient, the extent of the local involvement restricted the reconstructive choice; to achieve a safe and effective reconstruction of the excised area, gluteal myocutaneous flaps were the most appropriate option.…”

“…Any skin site may be affected but the oropharynx, genital/gluteal areas and soles are the most typical sites 2 . In 1954, Aird and coworkers described a variant of this tumour, defined as ‘epithelioma cuniculatum’ on the basis of its particular histological features 3 .…”

“…The ‘cuniculatum’ variant of the verrucous carcinoma is distinguished on the basis of microscopic features. Although verrucous carcinoma is possible at any cutaneous site, few cases of buttock involvement have been reported, 2,5 and the ‘cuniculatum’ type is considered relatively uncommon in this area 4,7 , 8 . Some authors hypothesize that the endophytic growth may be due to the effect of pressure, which may explain why verrucous ‘cuniculatum’ carcinoma is typically a plantar lesion.…”