Verrucous carcinoma of the axilla: case report and review

Assaf, Chalid; Steinhoff, Matthias; Petrov, Ignat; Geilen, Christoph C.; Villiers, Ethel Michele De; Schultz-Ehrenburg, U; Orfanos, Constantin E.

doi:10.1111/j.0303-6987.2004.00163.x

Cited by 24 publications

(34 citation statements)

References 52 publications

(66 reference statements)

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“…1,3 The local invasive potential of this neoplasm can lead to considerable tissue destruction. By contrast, metastases are exceptionally encountered.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Different causative factors have been implicated including trauma, chronic inflammation or ulceration, and human papillomavirus (HPV). 1,[3][4][5] Surgical excision and Mohs micrographic surgery represent the treatments of choice. 1,6 Other treatments have also been used with variable success including radiotherapy, cryosurgery, topical or systemic chemotherapy (bleomycin, 5-fluorouracil, cisplatin, methotrexate), carbon-dioxide laser, intralesional interferon alfa, and imiquimod.…”

mentioning

confidence: 99%

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Photodynamic therapy for cutaneous verrucous carcinoma

Nikkels

Thirion

Quatresooz

et al. 2007

Journal of the American Academy of Dermatology

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“…1,3 The local invasive potential of this neoplasm can lead to considerable tissue destruction. By contrast, metastases are exceptionally encountered.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Photodynamic therapy for cutaneous verrucous carcinoma

Nikkels

Thirion

Quatresooz

et al. 2007

Journal of the American Academy of Dermatology

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“…The majority of VCs in the head and neck region occur in the oral cavity, rarely arising in the respiratory or digestive tracts of the neck (1,2). VC presenting on the buccal and gingival mucosa is known as florid papillomatosis, while VC located on the plantar surface is referred to as carcinoma cuniculatum (3). Cutaneous VC of the head and neck predominantly occurs on the scalp, however, cutaneous VC of the neck is rare.…”

Section: Discussionmentioning

confidence: 99%

Immunohistochemical findings and differential diagnosis of papillary-type cutaneous verrucous carcinoma of the neck: A case report

et al. 2015

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Abstract. Verrucous carcinoma (VC) is a rare subtype of squamous cell carcinoma, with the majority of cases occurring in the oral cavity and genital area. The present study describes a rare case of cutaneous VC of the neck manifesting as a semi-pedunculated multinodular protrusion. Histological analysis revealed thickening of the epidermis and papillary growth. Although cellular atypia was generally mild, a large number of mitoses were observed, of which a small number were abnormal. Additionally, bulbous subepidermal invasion was observed. The lesion was differentiated from papillary squamous cell carcinoma, another rare subtype of squamous cell carcinoma, based on the presence of epidermal verrucous growth and the lack of remarkable nuclear atypia. Benign disorders, including seborrheic keratosis, fibroepithelial polyp, verruca vulgaris and pseudocarcinomatous hyperplasia, were also differentiated from the lesion. Immunohistochemical analysis of cytokeratin (CK)10 expression revealed attenuated staining of the lesion, therefore, anti-CK10 immunohistochemistry may be valuable in the diagnosis of VC.

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“…El concepto clínico y patológico del carcinoma verrrucoso se originó en 1948, cuando Lauren V. Ackerman describe una neoplasia de la cavidad oral en 31 pacientes, que posteriormente se describió en otras localizaciones como los pies 24,25,26 . Las características clínicas la relacionan con un lento crecimiento y una invasión con displasia mínima, y biológicamente con una baja incidencia y grado bajo de metástasis 27,28,29,30 .…”

Section: Discussionunclassified

Carcinoma verrucoso plantar. A propósito de un caso poco frecuente

López‐López

Sanz

Ponce

et al. 2013

Rev. Int. Cienc. Podol.

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Los autores declaran no tener ningún tipo de interés económico o comercial. RESUMEN Antecedentes:Los carcinomas verrucosos en pocas ocasiones se mencionan en la literatura su localización en la planta de los pies, siendo una variante bien diferenciada del carcinoma de células escamosas visto en mucosa y piel, incluyendo los pies. Objetivo: Describir las características clínicas, histopatológicas y de laboratorio y los resultados de un caso clínico inusual de un carcinoma verrucoso en la planta del pie. Métodos: Presentamos un extraño caso de un carcinoma verrucoso en la planta del pie izquierdo, a nivel del primer metatarsiano, que fue resecado completamente y se quedó sin evidencia de recidiva tumoral o metástasis, durante el seguimiento en un periodo de 4 años. Sobre esta base, se revisaron los casos publicados de carcinoma verrucoso en el pie, para definir las peculiaridades de este tumor poco común y para dar recomendaciones diagnósticas y terapéuticas. Resultados: El carcinoma verrucoso se caracteriza por una presentación clínica lenta pero inexorablemente amplia de aspecto similar a la verruga plantar, la histología típica es una invasión local mínima con baja incidencia de metástasis y buen pronóstico. Para el diagnóstico correcto, tanto el examen físico y el complementario debe ser exhaustivo y realizado mediante biopsia quirúrgica. La resección radical es el tratamiento de elección con confirmación histológica de los márgenes de resección libres del tumor. Conclusiones: El carcinoma verrucoso plantar puede presentar dificultad diagnóstica, la resección quirúrgica completa de la lesión permite el diagnóstico, presenta un buen pronóstico y pronta curación. Palabras clave: carcinoma verrucoso; epitelioma cuniculatum; carcinoma de células escamosas; tumor.http://dx

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Verrucous carcinoma of the axilla: case report and review

Abstract: Verrucous carcinoma should be distinguished from typical squamous cell carcinoma. The clinicopathological features, differential diagnosis, and therapy are discussed here together with the molecular biologic aspects of the tumor.

Cited by 24 publications

References 52 publications

Photodynamic therapy for cutaneous verrucous carcinoma

Photodynamic therapy for cutaneous verrucous carcinoma

Immunohistochemical findings and differential diagnosis of papillary-type cutaneous verrucous carcinoma of the neck: A case report

Carcinoma verrucoso plantar. A propósito de un caso poco frecuente

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