Verrucous and macular sarcoidosis

Warty papules on the nose

“…The majority of patients reported with VS are of African descent, have pulmonary disease, and present with verrucous lesions on their legs. Clinically, these lesions appear as well‐demarcated, exophytic, and hyperkeratotic papules or plaques 3,4 . Histopathologically, VS demonstrates verrucous epidermal hyperplasia with noncaseating sarcoidal granulomas in the dermis.…”

“…Management of VS is based on the degree of skin involvement and rapidity of disease progression. For localized disease, intralesional or topical corticosteroid therapy is the preferred first‐line treatment 3 . Particularly for thicker or nodular lesions, intralesional therapy may penetrate the skin better and yield better results.…”

“…Particularly for thicker or nodular lesions, intralesional therapy may penetrate the skin better and yield better results. For extensive disease, antimalarials (hydroxychloroquine or chloroquine), tetracycline derivatives, and methotrexate may be used 3 . Oral glucocorticoids are also another form of treatment, but they are generally reserved for cases that are rapidly spreading or progressively worsening.…”

“…Oral glucocorticoids are also another form of treatment, but they are generally reserved for cases that are rapidly spreading or progressively worsening. VS, in particular, has been shown to respond well to topical and systemic glucocorticoids 3 …”