Verrucous sarcoidosis associated with human papillomavirus infection: A case report

Noparstak, Michael; McDaniel, Brianna; King, Joy; Rády, Peter L.; Killipara, Ramya; Tyring, Stephen K.

doi:10.1016/j.jdcr.2015.05.006

Cited by 6 publications

(8 citation statements)

References 13 publications

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“…Two cases have been noted in white women, one without systemic involvement at the time of diagnosis [5], our patient also presented with disease limited to the skin. VS most commonly affects the lower extremities, although 5 cases have been reported on the face [5,[8][9][10]. Most of previous cases describe improvement with topical, intralesional and systemic corticosteroids [3].…”

Section: Resultsmentioning

confidence: 99%

An Unusual Variant of Cutaneous Sarcoidosis

Mansouri¹,

Sqalli²,

Ismaïli³

et al. 2018

Clin Med Img Lib

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Sarcoidosis is a multisystem inflammatory disease of unknown etiology, characterized by noncaseating granuloma variably infiltrating the respiratory tract, ganglions, eyes, internal organs and the skin. The heterogeneity of cutaneous sarcoidosis represents a diagnostic challenge for physicians and affirms its reputation as a "great imitator". Common specific lesions associated with sarcoidosis are papules, plaques, nodules, scar sarcoidosis and lupus pernio. Atypical presentations of sarcoidosis do exist and include ichthyosiform, alopecic, erythrodermic, angiolupoid and verrucous variants. Verrucous sarcoidosis is an extremely rare manifestation. Previous reports of this phenotype are limited to 16 cases, with only 5 previous reports of facial verrucous sarcoidosis reported in the literature. Here we report a case of a 50-year-old Moroccan woman who had an unusual cutaneous presentation of facial verrucous sarcoidosis. IMAGE ARTICLE Check for updates Discussion Variability in the cutaneous features of sarcoidosis affirms the condition's designation as one of dermatology's "great imitators" [2]. The diagnosis often requires a clinical presentation congruent with histologic features in addition to exclusion of confounding aetiologies [3]. Verrucous sarcoidosis (VS) is an extremely rare subtype [4], with only 16 cases previously reported [5]. It was first

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Section: Resultsmentioning

confidence: 99%

An Unusual Variant of Cutaneous Sarcoidosis

Mansouri¹,

Sqalli²,

Ismaïli³

et al. 2018

Clin Med Img Lib

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show abstract

“…1,7,8 Most of previously reported cases of verrucous sarcoidosis presented on the extremities, although 4 cases have been reported on the face. 3,[9][10][11] Previous cases describe improvement with topical, intralesional, and systemic corticosteroids. Tetracyclines, hydroxychloroquine, and steroid-sparing immunosuppressants of the antimetabolite class, including methotrexate, azathioprine, and mycophenolate, have also shown efficacy in the treatment of cutaneous sarcoidosis.…”

Section: Discussionmentioning

confidence: 99%

“…1,7,8 Most of previously reported cases of verrucous sarcoidosis presented on the extremities, although 4 cases have been reported on the face. 3,9-11…”

Section: Discussionmentioning

confidence: 99%

Filiform Verrucous Sarcoidosis of the Face: A Warty Report

2018

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Sarcoidosis is a multisystem inflammatory condition of unknown etiology. Variability in the cutaneous features of sarcoidosis is profound, and its protean manifestations affirm the condition's designation as one of dermatology's "great mimics." Cutaneous phenotypes of sarcoidosis include but are by no means limited to ichthyosiform, alopecic, erythrodermic, angiolupoid, and verrucous variants. Verrucous sarcoidosis is an exceedingly rare manifestation, and previous reports of this phenotype are limited to 15 cases. Most cases in the extant literature presented on the extremities, with clinical features mimicking that of a common wart, or as verrucous crateriform nodules, ulcers, or cutaneous horns. Only 4 previous reports of facial verrucous sarcoidosis exist in the literature, and to our knowledge, no prior cases have demonstrated filiform lesion morphology. Here we present a case of filiform verrucous sarcoidosis in an otherwise healthy, middle-aged African American man, devoid of internal organ involvement and limited to the face, histopathologically confirmed by the presence of characteristic granulomata devoid of lymphocytic infiltrates.

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“…Skin manifestations of sarcoidosis occur in up to 30% of cases, and may be the sentinel sign of the disease [ 1 ]. Cutaneous lesions in sarcoidosis can be divided histologically into specific containing granulomas or reactive nonspecific non-possessing granulomas [ 2 - 4 ]. Sarcoidosis specific lesions are commonly plaques, papules, nodules, scar sarcoidosis or lupus pernio, occurring in a symmetric distribution with a predilection for the face, upper trunk and extremities [ 3 - 5 ].…”

Section: Introductionmentioning

confidence: 99%

Verrucous sarcoidosis: a diagnosis to keep in mind

Nabli¹,

Gammoudi²,

Aounallah³

et al. 2020

Pan Afr Med J

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Skin manifestations of sarcoidosis occur in up to 30% of cases, and may be the sentinel sign of the disease, with the skin being sometimes exclusively affected. While this may facilitate an early dermatologic diagnosis, heterogeneity in the cutaneous morphologies of sarcoidosis complicates recognition and affirms its reputation as a “great imitator”. Here, we present a case of a verrucous version of sarcoidosis that may be misdiagnosed because it can mimic other inflammatory and neoplastic skin disorders. Although it is a rare variant, its presence should alert clinicians to the likelihood of systemic involvement of cutaneous sarcoidosis.

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Verrucous sarcoidosis associated with human papillomavirus infection: A case report

Cited by 6 publications

References 13 publications

An Unusual Variant of Cutaneous Sarcoidosis

An Unusual Variant of Cutaneous Sarcoidosis

Filiform Verrucous Sarcoidosis of the Face: A Warty Report

Verrucous sarcoidosis: a diagnosis to keep in mind

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