Verruciform Xanthoma in Association with Milroy Disease and Leaky Capillary Syndrome

Wu, Jashin J.; Wagner, Annette

doi:10.1046/j.1525-1470.2003.03010.x

Cited by 16 publications

(12 citation statements)

References 19 publications

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“…The key to clarify the disease pathophysiology of VX lies in the clarification of lipid source. The serum lipoprotein origin is supported by VX developed on a background of chronic local circulatory disturbance (Huguet et al , 1995; Kishimoto et al , 1998; Wu and Wagner, 2003). In our opinion, certain histologic differences can be appreciated from the figures in these cases and this theory does not satisfactorily explain why foam cells selectively target to the sub‐basal papillae.…”

Section: Discussionmentioning

confidence: 99%

Cellular basis of verruciform xanthoma: immunohistochemical and ultrastructural characterization

et al. 2007

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Section: Discussionmentioning

confidence: 99%

Cellular basis of verruciform xanthoma: immunohistochemical and ultrastructural characterization

et al. 2007

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“…VXs manifest as exophytic, polypoid growths and display characteristic pathological features comprising verrucous hyperplasia of the epidermis and lipid‐laden (foamy/xanthomatous) cells within the dermal papillae. Although most VXs occur in otherwise healthy persons, five cases have been reported in the setting of immunosuppression (bone marrow transplantation, 2–4 HIV infection 5 and common variable immunodeficiency disease) 6 . We report here the first case of VX developing in the setting of solid organ transplantation.…”

mentioning

confidence: 90%

Verruciform xanthoma of the scrotum in a renal transplant patient

Kanitakis¹,

Euvrard²,

Butnaru³

et al. 2004

Br J Dermatol

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Influence of environmental temperature on the occurrence of non-necrotizing cellulitis of the leg SIR, Non-necrotizing cellulitis of the leg is a common cutaneous bacterial infection whose risk factors include venous insufficiency, lymphoedema and toe-web intertrigo. The role of environmental temperature remains controversial. 1 To study the relationship between environmental temperature and the frequency of non-necrotizing cellulitis of the leg, we reviewed all patients hospitalized with nonnecrotizing cellulitis of the leg in a university hospital in a temperate region of France during a 4-year period, and correlated findings with the local environmental temperature during the same period.Patients included in this study were consecutive patients referred for non-necrotizing cellulitis of the leg from January 1995 to December 1998 in the Departments of Dermatology, Internal Medicine and Infectious Diseases of the Rouen University Hospital. The diagnosis of cellulitis of the leg was retrospectively identified using the database of the Medical Information System. The mean and maximum temperatures of each the 8 days prior to the date of hospital admission were obtained from the local meteorological unit for each case. Correlations between the mean and maximum daily temperature of each day from day ) 8 to the admission day (lag 0-8 days) and the daily number of patients hospitalized for cellulitis of the leg were studied using a nonparametric Poisson regression model to adjust for time trends and days of the week (generalized additive model). 2 Eight hundred and ninety-eight patients with cellulitis of the leg [342 men (38%) and 556 women (62%)] were

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“…Pathogenetically speaking, lymphedema is initially characterized by edema and excess tissue protein, but it soon evolves into chronic inflammation and fibrosis and eventually hyperkeratosis, verrucous‐like skin, and elephantiasis. Xanthomas associated with lymphedema have been described in the dermatologic literature since the 1960s (2,3) in the form of isolated case reports (4–7). We believe that our patient developed verruciform xanthomas in the setting of a primary lymphedema.…”

Section: Discussionmentioning

confidence: 99%