Verruca vulgaris: Novel treatment with a 1064 nm Nd:YAG laser

Abstract

Low-energy 1064 nm Nd: YAG laser treatment may be a promising, safe, and effective therapeutic modality for the treatment of VV. However, more treatment sessions may be needed for complete clearance and increased efficacy in some subjects.

Treatment Of Verruca Vulgaris with Long Pulsed Nd:YAG Laser 1064 nm In Iraqi Patients

“…David Goldberg et al (18) , 25 adult subjects with a total of 63 hand verrucae in a clinical trial were treated with a low energy (200mjoule) 1064nm Nd:YAG laser. Each subject was eligible for 3 treatments administered at monthly intervals.…”

Human Papillomavirus Infection: Management and Treatment

“…Here, thermal damage is very less leading to less inflammation and less scarring [60]. Non-ablative lasers are largely replacing ablative CO 2 lasers as side effects are less, both for patients and clinicians [61]. Er:YAG laser emits 2940 nm wavelength.…”

“…Its mechanism of action in treating warts is through direct ablation of the lesion in the epidermis, layer by layer until normal tissue is visualised. This laser type also has bactericidal effects [61]. Er:YAG laser was tried in all types of common warts-periungual, subungual and plantar warts; complete clearance rate was 68% for plantar warts, 78% for periungual warts and 76% for subungual warts.…”

“…A long pulsed Nd:YAG laser emits 1064 nm wavelength light, in infrared spectrum, in longer wavelength with lower haemoglobin, and melanin absorption coefficients allows deeper delivery of higher energy in hyperkeratotic and thicker epidermis that are assisted with warts [75]. Several studies have evaluated the use of the Nd:YAG laser in the treatment of simple and recalcitrant common, palmoplantar, periungual and subungual warts, with efficacies ranging from 46 to 100% [61,[76][77][78]. Laser protocol varied among different studies: spot size between 3 and 7 mm, pulse duration of 1-20 ms, fluence of 100-200 J/cm 2 , cooling methods, number of pulses between 1 and 8, treatment interval from 2 weeks to 12 months and mean number of treatments between 1.49 and 4.65.…”

“…After a mean of 1.49 treatments, wart clearance rate was 96% though there were differences in clearance rates after initial treatment depending on location (72.6% for common warts vs. 44.1% for palmoplantar warts) [76]. For determination of effectiveness and safety of a novel 100 microsecond pulsed 1064 nm Nd:YAG laser in treatment of Verruca vulgaris, low energy (200 mjouls) Nd:YAG, in monthly intervals for 3 months was given to 25 patients with lesion on hands-nineteen patients had complete clearance; with minimal discomfort [61]. At least partial response (50% reduction) in verruca size was noticed in all lesions [61].…”