Human Papillomavirus Infection: Management and Treatment

Abstract

Human papillomavirus infections are very common and recurrent. Their presentation varies according to their site of affection. Spontaneous recovery is common in a good number of patients. An ideal wart therapy resolves all or maximum number of warts, is painless, needs only one or a part of a wart treated, needs only minimum number of treatments, leaves no scar, offers lifetime HPV immunity and is easily available for all patients. Various modalities of treatment are available-from some folk and alternative therapies to destructive, antimitotic, virucidal, immunotherapy and combination of therapies. In every modality, the result is significant. Younger individuals with short duration of illness usually have the highest clearance rates for various treatments. Recurrence rate is also high in almost every treatment modality. Immunotherapy has a promising role.

Effectiveness of topical application of 15℅ salicyclic acid and 0.1℅ diphencyprone combined in an ointment form for treatment of plantar warts

“…Studies comparing two treatments found them equally effective with no difference in effectiveness of the two. However, studies on combined treatment of cryotherapy and 70% salicylic acid were very effective and showed 89% eradication rate in 86.2% of patients 26 .…”

Comparative Study Between Treatment with Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter Warts

“…Warts are more common in people with HPV because the virus disrupts the epithelial barrier [5]. There are over a hundred different forms of the HPV virus, so even though some warts go away on their own after a few years, others may need medical attention [6].…”

New Approach to create an Effective Natural Treatments of Infections caused by Human Papillomavirus

“…Because trichloroacetic acid can damage the skin around the wart, it is applied in the doctor's office. The treatment can be repeated weekly, as needed 19 . Alongside the pharmacological treatment or surgical resection, which has become a part of the conventional procedure, there is another option consisting of the treatment based on using natural products, i.e., extracts of vegetable origin and essential oils (in particular cold-pressed and etheric oils) 20 .…”