Vergleich zwischen TCI-TIVA, manueller TIVA und balanzierter Anästhesie während stereotaktischer Gewebsentnahme in der Neurochirurgie

Weninger, B.; Czerner, Stephan; Steude, U.; Weninger, E.

doi:10.1055/s-2004-814363

Cited by 9 publications

(2 citation statements)

References 13 publications

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“…Most studies comparing TCI and manual infusion groups have shown similar changes in blood pressure, HR, and hemodynamic instability occurrences [ 17 , 18 , 19 ]. Although a few studies have reported statistically significant differences in blood pressure or HR, these differences were generally not considered clinically significant [ 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

Hypotension after Anesthesia Induction: Target-Controlled Infusion Versus Manual Anesthesia Induction of Propofol

Yildirim

Doğan

Sarıkaya

et al. 2023

JCM

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Background: Post-induction hypotension frequently occurs and can lead to adverse outcomes. As target-controlled infusion (TCI) obviates the need to calculate the infusion rate manually and helps safer dosing with prompt titration of the drug using complex pharmacokinetic models, the use of TCI may provide a better hemodynamic profile during anesthesia induction. This study aimed to compare TCI versus manual induction and to determine the hemodynamic risk factors for post-induction hypotension. Methods: A total of 200 ASA grade 1–3 patients, aged 24 to 82 years, were recruited and randomly assigned to the TCI (n = 100) or manual induction groups (n = 100). Hemodynamic parameters were monitored with the pressure-recording analytic method. The propofol dosage was adjusted to keep the Bispectral Index between 40 and 60. Results: Post-induction hypotension was significantly higher in the manual induction group than in the TCI group (34% vs. 13%; p < 0.001, respectively). The propofol induction dose did not differ between the groups (TCI: 155 (135–180) mg; manual: 150 (120–200) mg; p = 0.719), but the induction time was significantly longer in the TCI group (47 (35–60) s vs. 150 (105–220) s; p < 0.001, respectively). In the multivariable Cox regression model, the presence of hypertension, stroke volume index (SVI), cardiac power output (CPO), and anesthesia induction method were found to predict post-induction hypotension (p = 0.032, p = 0.013, p = 0.024, and p = 0.015, respectively). Conclusion: TCI induction with propofol provided better hemodynamic stability than manual induction, and the presence of hypertension, a decrease in the pre-induction SVI, and the CPO could predict post-induction hypotension.

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Section: Discussionmentioning

confidence: 99%

Hypotension after Anesthesia Induction: Target-Controlled Infusion Versus Manual Anesthesia Induction of Propofol

Yildirim

Doğan

Sarıkaya

et al. 2023

JCM

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“…There were few other previous studies comparing these two techniques without assessing the outcome of the patients. Bastola et al compared propofol, sevoflurane and desflurane to determine the ideal neuro anaesthetic agent in elective craniotomy patients for supratentorial tumours, based on their haemodynamic effects, the relaxation of the brain and the characteristics of emergence (13 (14).…”

Section: Discussionmentioning

confidence: 99%

Target-controlled Infusion Propofol Versus Sevoflurane Anaesthesia for Emergency Traumatic Brain Surgery: Comparison of the Outcomes

Hassan

Nasir

Zaini

et al. 2017

MJMS

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Methods: A total of 110 severe TBI patients, aged 18-60, who underwent emergency brain surgery were randomised into Group T (TCI) (n = 55) and Group S (sevoflurane) (n = 55). Anaesthesia was maintained in Group T with propofol target plasma concentration of 3-6 µg/mL and in Group S with minimum alveolar concentration (MAC) of sevoflurane 1.0-1.5. Both groups received TCI remifentanil 2-8 ng/mL for analgesia. After the surgery, patients were managed in the intensive care unit and were followed up until discharge for the outcome parameters.Results: Demographic characteristics were comparable in both groups. Differences in Glasgow Outcome Scale (GOS) score at discharge were not significant between Group T and Group S (P = 0.25): the percentages of mortality (GOS 1) [27.3% versus 16.4%], vegetative and severe disability (GOS 2-3) [29.1% versus 41.8%] and good outcome (GOS 4-5) [43.6% versus 41.8%] were comparable in both groups. There were no significant differences in other outcome parameters.Conclusion: TCI propofol and sevoflurane anaesthesia were comparable in the outcomes of TBI patients after emergency surgery.

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Intravenous versus inhalational techniques for rapid emergence from anaesthesia in patients undergoing brain tumour surgery

Prabhakar

Singh

Mahajan

et al. 2016

Cochrane Database of Systematic Reviews

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Vergleich zwischen TCI-TIVA, manueller TIVA und balanzierter Anästhesie während stereotaktischer Gewebsentnahme in der Neurochirurgie

Cited by 9 publications

References 13 publications

Hypotension after Anesthesia Induction: Target-Controlled Infusion Versus Manual Anesthesia Induction of Propofol

Hypotension after Anesthesia Induction: Target-Controlled Infusion Versus Manual Anesthesia Induction of Propofol

Target-controlled Infusion Propofol Versus Sevoflurane Anaesthesia for Emergency Traumatic Brain Surgery: Comparison of the Outcomes

Intravenous versus inhalational techniques for rapid emergence from anaesthesia in patients undergoing brain tumour surgery

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